Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone-lysine N-methyltransferase

Gene

Dsim\GD11928

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Name:Dsim\GD11928Imported
ORF Names:Dsim_GD11928Imported, GD11928Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0183667. Dsim\GD11928.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

KOiK11422.
OrthoDBiEOG72JWHB.
PhylomeDBiB4NTK6.

Family and domain databases

InterProiIPR024657. COMPASS_Set1_N-SET.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4NTK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQDIRNINLG NNSGNSHDSS LATSKMPRNF KLLSDPQLVK CGTRLYRYDG
60 70 80 90 100
LMPGDPSYPT ITPRDPRNPL IRIRARAVEP LMLLIPRMFL NNTHWVDHCT
110 120 130 140 150
TDRAFWPPPT KKRRKDDELM RHKTGCARTE GFYKLDVREK AKHKYHHAKA
160 170 180 190 200
NTEDSFNEDR SDEPTALTNH HHNKLISKMQ GISREARSNQ RRLLTAFGSM
210 220 230 240 250
GESELLKFNQ LKFRKKQLKF AKSAIHDWGL FAMEPIAADE MVIEYVGQMI
260 270 280 290 300
RPVVADLRET KYEAIGIGSS YLFRIDMETI IDATKCGNLA RFINHSCNVS
310 320 330 340 350
ITGYFDIMLP TYNFVFQPNC YAKVITIESE KKIVIYSKQP IGINEEITYD
360 370
YKFPLEEEKI PCLCGAQGCR GTLN
Length:374
Mass (Da):43,029
Last modified:September 23, 2008 - v1
Checksum:i27F84E0E918951CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH983192 Genomic DNA. Translation: EDX15664.1.
RefSeqiXP_002076709.1. XM_002076673.1.

Genome annotation databases

EnsemblMetazoaiFBtr0211838; FBpp0210330; FBgn0183667.
GeneIDi6739816.
KEGGidsi:Dsim_GD11928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH983192 Genomic DNA. Translation: EDX15664.1.
RefSeqiXP_002076709.1. XM_002076673.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0211838; FBpp0210330; FBgn0183667.
GeneIDi6739816.
KEGGidsi:Dsim_GD11928.

Organism-specific databases

FlyBaseiFBgn0183667. Dsim\GD11928.

Phylogenomic databases

KOiK11422.
OrthoDBiEOG72JWHB.
PhylomeDBiB4NTK6.

Family and domain databases

InterProiIPR024657. COMPASS_Set1_N-SET.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MixedImported.

Entry informationi

Entry nameiB4NTK6_DROSI
AccessioniPrimary (citable) accession number: B4NTK6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.