B4NSM9 (B4NSM9_DROSI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
tRNA pseudouridine synthase RuleBase RU003792
EC=5.4.99.- RuleBase RU003792

Gene names

Name:	Dsim\GD15210 EMBL EDX15607.1
ORF Names:	Dsim_GD15210 EMBL EDX15607.1, GD15210 FlyBase FBgn0186880

Organism

Drosophila simulans (Fruit fly) [Complete proteome]

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	tRNA uridine = tRNA pseudouridine. RuleBase RU003792
Sequence similarities	Belongs to the tRNA pseudouridine synthase TruA family. RuleBase RU003792

Ontologies

Keywords
Biological process	tRNA processing RuleBase RU003792
Molecular function	Isomerase RuleBase RU003792
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pseudouridine synthesis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro pseudouridine synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4NSM9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: F05A60DD21A23B1F	FASTA	498	57,603
	10 20 30 40 50 60 MSATNDKKVV INKRLKGLSR EALEKLTQTE LIDKVVQLEA YNFQLRNLLQ KKLSEHDKHD 70 80 90 100 110 120 KEYSGLFGNE ADGKVSQVAK TSNKVQKIRM FDWSSAHKRH VLLKITYFGW DYQGFACQED 130 140 150 160 170 180 SNDTIESNLF RALTRTCLIE SRATSNYHRC GRTDKEVSAF CQVISIDLRS KHPPESQLDP 190 200 210 220 230 240 TSLSSEIDYC GLLNRVLPKN IQCVAWMPLR SPVYSARFDC VSRSYRYYFP KGDLDIAAMR 250 260 270 280 290 300 KACDLLVRHA DFRNFCKMDV HNGVTNYMRN LQSARVEACD ENHTNSGYDM YYLEIQANAF 310 320 330 340 350 360 LWHQIRCIMA VLLLVGQKKE KPAVISDLLD VESNPCKPQY TPAIGLPLNL FRCDFRDHTT 370 380 390 400 410 420 RSVNHSGSGD ANEEAMDTVA NESDDLNAPE PLERDLTAWI YNEENLQKLI ENTQCEWTQF 430 440 450 460 470 480 SVKSTMIRNV LQQLESLFEE NFKPNEKVLA QVNLLQDSVN PRQYQPLLER KRCESLENRI 490 EHFVKKQRLI VKNETETE

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mixed EMBL EDX15607.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH982367 Genomic DNA. Translation: EDX15607.1.
RefSeq	XP_002076382.1. XM_002076346.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0215120; FBpp0213612; FBgn0186880.
GeneID	6739485.
KEGG	dsi:Dsim_GD15210.
Organism-specific databases
FlyBase	FBgn0186880. Dsim\GD15210.
Phylogenomic databases
KO	K01855.
OrthoDB	EOG4N5TCH.
Family and domain databases
Gene3D	3.30.70.580. 1 hit. 3.30.70.660. 1 hit.
InterPro	IPR020103. PsdUridine_synth_cat_dom. IPR001406. PsdUridine_synth_TruA. IPR020097. PsdUridine_synth_TruA_a/b_dom. IPR020095. PsdUridine_synth_TruA_C. IPR020094. PsdUridine_synth_TruA_N. [Graphical view]
PANTHER	PTHR11142. PTHR11142. 1 hit.
Pfam	PF01416. PseudoU_synth_1. 2 hits. [Graphical view]
SUPFAM	SSF55120. PsdUridine_synth_cat_dom. 1 hit.
TIGRFAMs	TIGR00071. hisT_truA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4NSM9_DROSI

Accession

Primary (citable) accession number: B4NSM9

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)