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Protein

V-type proton ATPase subunit

Gene

Dwil\GK10228

Organism
Drosophila willistoni (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunitUniRule annotation
Gene namesi
Name:Dwil\GK10228Imported
ORF Names:Dwil_GK10228Imported, GK10228Imported
OrganismiDrosophila willistoni (Fruit fly)Imported
Taxonomic identifieri7260 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007798 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0212243. Dwil\GK10228.

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.UniRule annotation

Protein-protein interaction databases

STRINGi7260.FBpp0239371.

Family & Domainsi

Sequence similaritiesi

Belongs to the V-ATPase V0D/AC39 subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2957. Eukaryota.
COG1527. LUCA.
InParanoidiB4NDF5.
KOiK02146.
OMAiFMDFITY.
OrthoDBiEOG091G09L5.
PhylomeDBiB4NDF5.

Family and domain databases

Gene3Di1.20.1690.10. 2 hits.
InterProiView protein in InterPro
IPR002843. ATPase_V0-cplx_csu/dsu.
IPR016727. ATPase_V0-cplx_dsu.
IPR035067. V-type_ATPase_suC.
PANTHERiPTHR11028. PTHR11028. 1 hit.
PfamiView protein in Pfam
PF01992. vATP-synt_AC39. 1 hit.
PIRSFiPIRSF018497. V-ATP_synth_D. 1 hit.
SUPFAMiSSF103486. SSF103486. 1 hit.

Sequencei

Sequence statusi: Complete.

B4NDF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSSGFMFNI DNGYLEGLCR GFKCGILKQA DYLNLVQCET LEDLKLHLQG
60 70 80 90 100
TDYGSFLANE PSPLSVSVID DKLREKLVIE FQHMRNHAVE PLSNFLDFIT
110 120 130 140 150
YGYMIDNIIL LITGTLHQRP ISELIPKCHP LGSFEQMEAI HVASTPAELY
160 170 180 190 200
NAVLVDTPLA PFFVDCISEQ DLDEMNIEII RNTLYKAYLE AFYNFCKNMG
210 220 230 240 250
GATADVMCEI LAFEADRRAI IITINSFGTE LSKDDRAKLY PNCGKMYPDG
260 270 280 290 300
LAALARADDY EQVKTVAEYY AEYAALFDGS GNNPGDKTLE DKFFEHEVKL
310 320 330 340 350
NVYAFLQQFH FGVFYAYLKL KEQECRNIVW IAECVAQKHR AKIDNYIPIF
Length:350
Mass (Da):39,851
Last modified:September 23, 2008 - v1
Checksum:i3BF503F419FED02F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH964239 Genomic DNA. Translation: EDW82861.1.
RefSeqiXP_002071875.1. XM_002071839.2.

Genome annotation databases

EnsemblMetazoaiFBtr0240879; FBpp0239371; FBgn0212243.
GeneIDi6648724.
KEGGidwi:Dwil_GK10228.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB4NDF5_DROWI
AccessioniPrimary (citable) accession number: B4NDF5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 5, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported