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B4NCY3 (B4NCY3_DROWI) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1904 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS007728

S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.

Subcellular location

Nucleus By similarity.

Sequence similarities

Contains 1 SET domain. RuleBase RU004538

Contains 1 pre-SET domain.

Contains 6 ANK repeats. RuleBase RU003321

Contains SET domain. SAAS SAAS001214

Contains pre-SET domain. SAAS SAAS001214

Sequences

Sequence LengthMass (Da)Tools
B4NCY3 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: DAAF9819FE2369AE

FASTA1,904204,151
        10         20         30         40         50         60 
MTDFVELLNS MSTTFNSDCA TTTAEGGTLL NLDLAEDKTL KWRNLANNQF ACKDKEKKQQ 

        70         80         90        100        110        120 
PPTTTQTTSK GSDAIIDKNE DPASLEAAEQ STPAVTEQSD VTSEKVSSEL LEEEIEDNVK 

       130        140        150        160        170        180 
ELLADVIDAA AVKVEEEEKA AAVAATAKIA TESEEGAKAA ATTTASIAEL ADPPKTSFNE 

       190        200        210        220        230        240 
AKQPATEVPA DGNDNAPTAT TNTPNEVTAA AVDADVDVDV DANATASASV EIKIEETSRN 

       250        260        270        280        290        300 
AASVDSNDDR IKTETETQTK QVTNNQDNED EEEEESKSSA AAELELTTAT KATVKVKSAS 

       310        320        330        340        350        360 
PTTTTNSQLQ STAAAAAVAE IPTEAALVLA PLVVNSANDS VDVDVDVDVE ADATTTILTG 

       370        380        390        400        410        420 
NSAAAAEPTP AATAAVNADK NEQISPGSNT RRLRRTPRPT DTPTTTPTPL EEPQVDGGDI 

       430        440        450        460        470        480 
RTEVRPAKEE EEIESPIESN ELNEVKKEPE KCLASVDGIG IGDDVDAAAT VSSTSSTTPT 

       490        500        510        520        530        540 
EPPVVATVVA PPPPPKRGRG RAKKIKLDVE LPTNELIDGE NAYGDETMAT AISPTVVVER 

       550        560        570        580        590        600 
KQPGRKRKLP EEQQEAALIA SELATLVVKT ENQELEVSEI APSGSGVDPK RTRRSVRLGN 

       610        620        630        640        650        660 
RHPADPIVNA TWSEEVKTEP SVGGTSGADL VTTLSELPMP VLDEKTPPKK RGRKAKIPPT 

       670        680        690        700        710        720 
VKPNESQLAS TTTNHHSGQP LTNGNKRSTP TTTNANATAT TTTTSSSSSN VAGLGGSGEL 

       730        740        750        760        770        780 
QLPKRSKRRI KPTPKILEND ELRCEFETKH IERMTHWETA GADSDSHFET PQQSFSGGGG 

       790        800        810        820        830        840 
GGAGSNSSTS RQKSEKSDGS GFDVGGQHPA GTSAIKKRLF SKSQRDIENS GAALVAKSKV 

       850        860        870        880        890        900 
KPCPNVDKFL SDIKAAKLNA NRSPEERKLN KKQLRKLAKQ KEKHLKHLGL RRNNSEDASD 

       910        920        930        940        950        960 
DDSSNTDNEE FVPATPVQVG KPSLTLRLRN AAPKEQQVPT TSAAAAATAS QKAQHPSANS 

       970        980        990       1000       1010       1020 
VKLNRRVGVR TGVQSAAAAA AAAAMQSPLE PDQLHSLNSS ILAAAELNDT DAIPTTSNSS 

      1030       1040       1050       1060       1070       1080 
IKVKSSKFIC LCQKSSQYYA RNAPDSSYCC AIDNIDEQKI GCCNELSAEV HNLLRPSQRV 

      1090       1100       1110       1120       1130       1140 
GYMILCDDHK KRLQSHNCCA GCGIFCTQGK FVLCKQQHFF HPDCAQRFIL NSPFEGQQLL 

      1150       1160       1170       1180       1190       1200 
QSNNSNKFHS PMLVLKCPHC GLDTPERTST VTMKCQTLPV FLPTQKSKIK PAKLTTSAHL 

      1210       1220       1230       1240       1250       1260 
AQFAAGRSNS TVTASKSSTT GRGRPASSAN ASNTNATSTS AGAAAGAGAT GKSNGIRGGK 

      1270       1280       1290       1300       1310       1320 
ATATTAAVNA TSNSHNSGAA GGHTITFEQL IPDSVLNVVL RGHVVSASGR VTTEFTSRDM 

      1330       1340       1350       1360       1370       1380 
YYAVQNDDLE RVAEILAADY NVLAPMREYP GTCLHLVAHS GTLQMAYLLL CKGASSQDFV 

      1390       1400       1410       1420       1430       1440 
NVVDSELRTA LMCAVMNEKC DMLNLFLQCG ADVAIKGPDG KTSLHIAAKM GNVEATQLIV 

      1450       1460       1470       1480       1490       1500 
DSYRASRNIS NFLSFIDAQD EGGWTAMVWA AELGHTDIVS LLLNHGADPN ICDNDNNTVL 

      1510       1520       1530       1540       1550       1560 
HWSALHNDGL ETITVLLQAG ADCNVQNVEG DTPLHIACRH SVTRMCIALI ANGADLMIKN 

      1570       1580       1590       1600       1610       1620 
KAEQLPFDCI PNEESECGRT VGFNMQMRSF RPLGLRTRVV CADASNGREA RPIQAVRNEL 

      1630       1640       1650       1660       1670       1680 
TMSEHEDEAD TLMWPDFKYI TNCIILQNSV QIDRRVSQMR ICSCLDSCSS DLCQCNGASS 

      1690       1700       1710       1720       1730       1740 
QNWYTAESRL ISDFNYDDPA VIFECNDVCG CNQLSCRNRV VQNGTRIPLQ IVECEDPAKG 

      1750       1760       1770       1780       1790       1800 
WGVRALANVP KGTFVASYTG EILTAPEADR RTDDSYYFDL DNGHCIDANY YGNVTRFFNH 

      1810       1820       1830       1840       1850       1860 
SCEPNVLAVR VFYEHQDYRF PKIAFFACRD IDSGEEICYD YGEKFWRNEQ RANNGCKCLT 

      1870       1880       1890       1900 
SVCKYAGRLA ATSTNPSPMD REGFDGGDLL VSSAPPDEDF DVKA 

« Hide

References

[1]"Evolution of genes and genomes on the Drosophila phylogeny."
Drosophila 12 genomes consortium
Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Tucson 14030-0811.24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH964239 Genomic DNA. Translation: EDW82692.1.
RefSeqXP_002071706.1. XM_002071670.1.

3D structure databases

ProteinModelPortalB4NCY3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7260.FBpp0254141.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0255649; FBpp0254141; FBgn0226957.
GeneID6649151.
KEGGdwi:Dwil_GK24998.

Organism-specific databases

FlyBaseFBgn0226957. Dwil\GK24998.

Phylogenomic databases

eggNOGCOG0666.
InParanoidB4NCY3.
KOK11420.
OMAENDELRC.
OrthoDBEOG744T8D.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR017956. AT_hook_DNA-bd_motif.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
[Graphical view]
PfamPF12796. Ank_2. 2 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PRINTSPR01415. ANKYRIN.
SMARTSM00248. ANK. 6 hits.
SM00384. AT_hook. 3 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4NCY3_DROWI
AccessionPrimary (citable) accession number: B4NCY3
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)