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B4NBL6

- PTC71_DROWI

UniProt

B4NBL6 - PTC71_DROWI

Protein

Protein phosphatase PTC7 homolog fig

Gene

fig

Organism
Drosophila willistoni (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Magnesium or manganese.By similarityCurated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi86 – 861Manganese 1By similarity
    Metal bindingi86 – 861Manganese 2By similarity
    Metal bindingi87 – 871Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi231 – 2311Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: UniProtKB

    GO - Biological processi

    1. dephosphorylation Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase PTC7 homolog fig
    Alternative name(s):
    Fos intronic gene protein (EC:3.1.3.16)
    Gene namesi
    Name:figBy similarity
    ORF Names:GK19179
    OrganismiDrosophila willistoni (Fruit fly)
    Taxonomic identifieri7260 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000007798: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0221177. Dwil\GK19179.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 315315Protein phosphatase PTC7 homolog figPRO_0000377405Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi7260.FBpp0248322.

    Structurei

    3D structure databases

    ProteinModelPortaliB4NBL6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini49 – 307259PP2C-likeSequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Sequence Analysis
    Contains 1 PP2C-like domain.Sequence Analysis

    Phylogenomic databases

    eggNOGiCOG0631.
    InParanoidiB4NBL6.
    KOiK17508.
    OMAiKLMHYAQ.
    OrthoDBiEOG7DRJ3F.
    PhylomeDBiB4NBL6.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    [Graphical view]
    PfamiPF07228. SpoIIE. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4NBL6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSSLAGKLQ GKTKFLIDVL KFYDARMLKS SSMSGIGKRG DPYLVKVVQG    50
    RSRKHSIASA KDNHRYGEDS WFISSTPKAE VMGVADGVGG WSELGIDSGL 100
    FASELMFWCA NYAKRESFDG RTPLDLLIES YSEIKGKTDP IVGSSTACLV 150
    SLNRRDCTMH SANLGDSGFL VIRNGRMLHR SEEQVHDFNA PYQLTVVPNE 200
    RFDNVYCDRP ELADSTRLPL QEGDLVLLAT DGLFDNVPES LIVKTLGKYQ 250
    GVTREEDLQS AANSLVHMAK DLSISPNFES PFALKAKAFE VDYPGGGKPD 300
    DITVILATVA VPQND 315
    Length:315
    Mass (Da):34,550
    Last modified:September 23, 2008 - v1
    Checksum:iC106A5802B5C9AAA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH964232 Genomic DNA. Translation: EDW81180.1.
    RefSeqiXP_002070194.1. XM_002070158.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0249830; FBpp0248322; FBgn0221177.
    GeneIDi6647958.
    KEGGidwi:Dwil_GK19179.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH964232 Genomic DNA. Translation: EDW81180.1 .
    RefSeqi XP_002070194.1. XM_002070158.1.

    3D structure databases

    ProteinModelPortali B4NBL6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7260.FBpp0248322.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0249830 ; FBpp0248322 ; FBgn0221177 .
    GeneIDi 6647958.
    KEGGi dwi:Dwil_GK19179.

    Organism-specific databases

    FlyBasei FBgn0221177. Dwil\GK19179.

    Phylogenomic databases

    eggNOGi COG0631.
    InParanoidi B4NBL6.
    KOi K17508.
    OMAi KLMHYAQ.
    OrthoDBi EOG7DRJ3F.
    PhylomeDBi B4NBL6.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    [Graphical view ]
    Pfami PF07228. SpoIIE. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 14030-0811.24Imported.

    Entry informationi

    Entry nameiPTC71_DROWI
    AccessioniPrimary (citable) accession number: B4NBL6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3