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B4NBE8

- B4NBE8_DROWI

UniProt

B4NBE8 - B4NBE8_DROWI

Protein

DNA ligase

Gene

Dwil\GK11194

Organism
Drosophila willistoni (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dwil\GK11194Imported
    ORF Names:Dwil_GK11194Imported, GK11194Imported
    OrganismiDrosophila willistoni (Fruit fly)Imported
    Taxonomic identifieri7260 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000007798: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0213205. Dwil\GK11194.

    Interactioni

    Protein-protein interaction databases

    STRINGi7260.FBpp0240337.

    Structurei

    3D structure databases

    ProteinModelPortaliB4NBE8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    InParanoidiB4NBE8.
    KOiK10776.
    OMAiNEDNKLD.
    OrthoDBiEOG7BKCT2.
    PhylomeDBiB4NBE8.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4NBE8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATPLQNEDN KLDTFRRICD EIASESSYLR KVERLEGFFK KGSKGTVFEG    50
    DFLLWVQFLI PGATQRVYNL QNKALIKLFS RILNSDQNQM QLDLEQDGDV 100
    SETLRKHFAA SAKLKPQTQS KLYLQEVDEL LRQLEQKTKE DDQTELLKEL 150
    CKKATELDLR TFIRLIKQDL RINARARHIL DAFGPLAYPA YQSSRDLTAI 200
    VQQFAGKAVK TQAKSPAKKL KTTTSAIQVM TPISPMLANA CKSVEEAFKK 250
    NPAGLFGEVK YDGERVQIHK KGKEFKFFSR NLKPVMDHKI KRLTEYIPRA 300
    FPGAGDMILD SEIILVDTET GALLPFGTLG AHKKHEYANA SVCLFVFDCI 350
    LYDGEDLMQL EFRKRREILE QNIEPIKSYV QLSESQFLKT KSELAMMTAK 400
    VLQANLEGVV LKNPNGTYQP GKRNWLKVKK DYLFDGKMAD TADLVVLGAW 450
    YGSGKKGGVL SIFLMGCYDP KDRLWKTVTK VHSGLDDSTN DEIHENLMKL 500
    TTRADANKTP NWLLCKKSLV PDVLAVDPQK MPVWEITGAE FTKSEAHTAA 550
    GVSIRFPRIT RLRSDKTSKE ANDLPHLLNL YEASKKNVNV DLLLANCDND 600
    KDGLEKKLAQ EKTPEKRKSL ENSAKKSKKS ISKEDEDSQC SSKMIKREVN 650
    KPSQKGLQYY FKPDKIQNNV KSELKTEVKT ELKTQVKSET HTAMEVDENT 700
    PKQVKSKLFS GLVAHFTKDA TKSKQMQEFV QHGGSLTTNT QKAALAFYNT 750
    NTSVNLAHLR PLYRRRCRHL TVSWLDRSIE TQTLQPYPLY AVLLKS 796
    Length:796
    Mass (Da):90,397
    Last modified:September 23, 2008 - v1
    Checksum:i9A7EDCD0AE46B3E4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH964232 Genomic DNA. Translation: EDW81112.1.
    RefSeqiXP_002070126.1. XM_002070090.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0241845; FBpp0240337; FBgn0213205.
    GeneIDi6647378.
    KEGGidwi:Dwil_GK11194.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH964232 Genomic DNA. Translation: EDW81112.1 .
    RefSeqi XP_002070126.1. XM_002070090.1.

    3D structure databases

    ProteinModelPortali B4NBE8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7260.FBpp0240337.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0241845 ; FBpp0240337 ; FBgn0213205 .
    GeneIDi 6647378.
    KEGGi dwi:Dwil_GK11194.

    Organism-specific databases

    FlyBasei FBgn0213205. Dwil\GK11194.

    Phylogenomic databases

    eggNOGi COG1793.
    InParanoidi B4NBE8.
    KOi K10776.
    OMAi NEDNKLD.
    OrthoDBi EOG7BKCT2.
    PhylomeDBi B4NBE8.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 14030-0811.24Imported.

    Entry informationi

    Entry nameiB4NBE8_DROWI
    AccessioniPrimary (citable) accession number: B4NBE8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3