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B4MXM5

- B4MXM5_DROWI

UniProt

B4MXM5 - B4MXM5_DROWI

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Protein
Submitted name:

GK20252

Gene

Dwil\GK20252

Organism
Drosophila willistoni (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. chromatin binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
GK20252Imported
Gene namesi
Name:Dwil\GK20252Imported
ORF Names:Dwil_GK20252Imported, GK20252Imported
OrganismiDrosophila willistoni (Fruit fly)Imported
Taxonomic identifieri7260 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007798: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0222249. Dwil\GK20252.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7260.FBpp0249395.

Family & Domainsi

Sequence similaritiesi

Contains 1 post-SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiCOG5076.
InParanoidiB4MXM5.
KOiK06101.
OMAiLNDTHHY.
OrthoDBiEOG7ZPNJ4.
PhylomeDBiB4MXM5.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4MXM5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSDQNGATR AADKTKDQEQ QNPGPGPETG GSENEETTDT SQSQTQSIKS
60 70 80 90 100
SATQFSVVQR TDTDGLRMRI SAIRPLAPPP SLKTNCKMST TTTDSLSCFR
110 120 130 140 150
QEEITTNKSN KTSKKIKVKR KKLSHTDAVN PSKVRKSGGV AAASMGGIFS
160 170 180 190 200
SDSDDDLPLK VHQQRAPRLL LTAIAGHQAS GQAPPPPDSI GISSSDNELP
210 220 230 240 250
SLVQAAIKRV ESDTEDTSVS LGATGKSKHL PQYQSTLLQD FMEKTQMLGQ
260 270 280 290 300
HQLVGGGDRV KPKEETQPPA NPRKRRGRPK KLNPHIGSNL RAGSVVTARP
310 320 330 340 350
AAVNESADSG VISTTSTTQS TTPSPKMPNS SDPPQAQARG LDSAAGNSST
360 370 380 390 400
KIDMSYLDKR MYATERVLYP PPRNKRRQIK NPKNIKDAEQ VDPLWREIDV
410 420 430 440 450
NKKFRLRSMS VGASGGGGGS GRGGSGGVAS AICSKVLVAN SGYVSDYGSV
460 470 480 490 500
RHPHSSHSRS NHNSGYKSDA SCKSRYSVKS CVSRRSRAKS CGYRSDCKEG
510 520 530 540 550
GKSSIRLRRR RRPSTMIATT ADVEDQDILQ LAGLSLGQSS EESNEYISKP
560 570 580 590 600
SLQSLPSTSA SKKYGEINRY ITTGQYFSRE PNPSQNQNQP EAPFMSKMLL
610 620 630 640 650
NHRKDSSQAA SNAQSSCRFP CKIKSRRSSA ASMCSSYVSG VSRMLRRRHR
660 670 680 690 700
RNKSLQIDSK LLTEIEILTS TFHGRCRIQE DRLTGSSGKE KLLAEATKLK
710 720 730 740 750
ATTLNAAAPA STLAQHSLIV NGGLSGGLTG GTLTTAATTA SSTSSTGKPL
760 770 780 790 800
KRAMKKRKLS EPLVDFAMLS ASANANGDGV GGASNAQSSG AGSSKRRHKK
810 820 830 840 850
SQGSSTSSSP DDHKLPLKKR HYLLTPGERP PADSSNFANG KLNAEAWAAA
860 870 880 890 900
AATAKTTAST KSQAQFNARS AKSLLTPKKR HLLEHQSGGV TTTSASNSPL
910 920 930 940 950
RIVVDSNSSI SGGKLLDISP SSLGSLKQQK RASVASSNKQ KRDPATQLHS
960 970 980 990 1000
PAPSGSGSCP PPPPGIFEPS VELEIQIPLS KLNESVIITK SEVASPLLSL
1010 1020 1030 1040 1050
DIKEDTKKEM GQRVVESLLH KTGGNLLFKR KRKKINRTGF PTVRRKKRKV
1060 1070 1080 1090 1100
SLEQLQTEKS SEQMDQEQEQ QEQDPLSRET RSTNSNNPVQ NCERVPLVGE
1110 1120 1130 1140 1150
ARETFVARSN ARMTPRLSVV ALERLQRPQT PSRGRPRGRK PKDKLEQVTE
1160 1170 1180 1190 1200
SSAVASSAPP PPPPSEKTVA KKRGRRQVAK PEEEQEPAIA IPTPAKNKLL
1210 1220 1230 1240 1250
VEPNIKLPAG VDPNTNFSCK IRLKRRRNLE EITSKEIVSQ EELDKEAEAK
1260 1270 1280 1290 1300
RLDVIPSEHD PLPMQECTSS STLAIHSQQD YASCSESSED KLSTASRNKI
1310 1320 1330 1340 1350
SKLKKNYLVA GLLSNYYKQA TKPPPVKHQG GGKDSIAPSS GQRLMPPPPY
1360 1370 1380 1390 1400
CERYHRRTQI DFELPYDIWW AYTNAKLPLR HQVPSWNYRK IRTNVYAESV
1410 1420 1430 1440 1450
RPNLAGFDHP VCNCKESCMD NCLNRMVYTE CSATNCPSGD KCHNQKIHRH
1460 1470 1480 1490 1500
EVAPGVERFM TADKGWGVRT KLPIAKGTYI LEYVGEVVTE REFKQRMASI
1510 1520 1530 1540 1550
YLNDTHHYCL HLDGGLVIDG QRMGSDCRFV NHSCEPNCEM QKWSVNGLSR
1560 1570 1580 1590 1600
MVLFAKRQIR QGEELTYDYN FSLFNPSEGQ PCRCGMPQCR GVIGGKSQRV
1610 1620 1630 1640 1650
KPLPPIAAVS ADASPQRGGR QRKHKAKKHP QKGGTAAGGS GSMPLVNKLV
1660 1670 1680 1690 1700
QQLSERERKL AKQFNVFLVR NYEKIRRYKV KRSHKASSAI GASAASTSQG
1710 1720 1730 1740 1750
SLGGRRPSTP SSSSLLAAQI SALCTPRNIK TRGLAQAVQD PELEKMARMA
1760 1770 1780 1790 1800
VVLRDICQTI EGMNMTEILS LSAAACKQSK RKNAKNTNSA VSSSSSSSST
1810 1820 1830 1840 1850
TAGALQAGRL EFKGIQSMVE QGHYKSPQEF DAHMQQLFDE ARKTYTDDES
1860 1870 1880 1890 1900
KINLLQSLVE CYEQQKVSSY EQLVEILGDS VDLHGFKAKQ VEPQPTVEPA
1910 1920 1930 1940 1950
IKETQITPLP PPVATDDEDV ISCICGLYKD EGLMIQCSKC MVWQHTECTK
1960 1970 1980 1990 2000
ADINAENYQC ERCEPRKVDR EIPLDEFTEE GHRYYLSLMR GNDLQVRQGD
2010 2020 2030 2040 2050
AVYVLRDIPI KDNEEQKKHT YETIGKIDYQ ECDIFRVEHL WKNETGKRFI
2060 2070 2080 2090 2100
FGHHFLRPHE TFHEPTRRFY PNEVVRVSLY EVVPIELVIG RCWVLDRTTF
2110 2120 2130 2140 2150
CKGRPIECHD ESHCYICELR VDKSARFFSK TKASYPACTK SYAFRKFPER
2160 2170 2180 2190 2200
VKISKTYAPH DVDASMLKTK KQKTELEVAT TAKQQRITVR EGRRRQPRTA
2210 2220 2230 2240 2250
EPSYVATKSI GGVGTSNATA AVQVLTPTLP NGQLLKRKRS RLENVLITMK
2260 2270 2280 2290
LKCLDAQTAQ EQPIDLSYLL SGRGARQRKT NNNQTTTTSD LGHN
Length:2,294
Mass (Da):252,707
Last modified:September 23, 2008 - v1
Checksum:i84FD265C4F779916
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH963876 Genomic DNA. Translation: EDW76794.1.
RefSeqiXP_002065808.1. XM_002065772.1.

Genome annotation databases

EnsemblMetazoaiFBtr0250903; FBpp0249395; FBgn0222249.
GeneIDi6643058.
KEGGidwi:Dwil_GK20252.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH963876 Genomic DNA. Translation: EDW76794.1 .
RefSeqi XP_002065808.1. XM_002065772.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7260.FBpp0249395.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0250903 ; FBpp0249395 ; FBgn0222249 .
GeneIDi 6643058.
KEGGi dwi:Dwil_GK20252.

Organism-specific databases

FlyBasei FBgn0222249. Dwil\GK20252.

Phylogenomic databases

eggNOGi COG5076.
InParanoidi B4MXM5.
KOi K06101.
OMAi LNDTHHY.
OrthoDBi EOG7ZPNJ4.
PhylomeDBi B4MXM5.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
InterProi IPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF01426. BAH. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14030-0811.24Imported.

Entry informationi

Entry nameiB4MXM5_DROWI
AccessioniPrimary (citable) accession number: B4MXM5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3