B4MP81 (EIF3J_DROWI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 3 subunit J
Short name=eIF3j

Gene names

Name:	Adam
ORF Names:	GK21662

Organism

Drosophila willistoni (Fruit fly) [Complete proteome]

Taxonomic identifier

7260 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity.
Subunit structure	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the eIF-3 subunit J family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Eukaryotic translation initiation factor 3 subunit J		PRO_0000365142
Experimental info
	Sequence conflict	119	1	T → A in AAO01104. Ref.1
	Sequence conflict	171	1	L → V in AAO01104. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	B4MP81 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 3E6D83D75B1FACF6	FASTA	236	27,120
	10 20 30 40 50 60 MADDWESAAD SEVVILPNAA NNINKWEGED DDEDVKESWE DEEEKKDEEK PTKTEVPVKP 70 80 90 100 110 120 KPTRALKAKL EEEERLREAE EEKRLANLTP EEKFAEKLRV KKMQEESDMK HTLDTFGVTS 130 140 150 160 170 180 ISGGLESFNP ESKEEFKEFG DTLSWKVAQF KESPHFPQFV EDLVRSICVN LSAADIKKVK 190 200 210 220 230 INVELLHSEK LKLEKANTKK PIGKGKGKVS LRTENDDIDG YQKYGNDFTD DYDDFM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome." Bergman C.M., Pfeiffer B.D., Rincon-Limas D.E., Hoskins R.A., Gnirke A., Mungall C.J., Wang A.M., Kronmiller B., Pacleb J.M., Park S., Stapleton M., Wan K.H., George R.A., de Jong P.J., Botas J., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0086.1-RESEARCH0086.20(2002) [PubMed: 12537575] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed: 17994087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tucson 14030-0811.24.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY190959 Genomic DNA. Translation: AAO01104.1. CH963849 Genomic DNA. Translation: EDW73920.1.
RefSeq	XP_002062934.1. XM_002062898.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4MP81.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0252313; FBpp0250805; FBgn0064303.
GeneID	6640598.
KEGG	dwi:Dwil_GK21662.
Organism-specific databases
FlyBase	FBgn0064303. Dwil\Adam.
Phylogenomic databases
OMA	ISHRIKP.
OrthoDB	EOG4VDNGC.
PhylomeDB	B4MP81.
Family and domain databases
InterPro	IPR023194. eIF3-like_dom. IPR013906. eIF3_subunit. [Graphical view]
Gene3D	G3DSA:1.10.246.60. G3DSA:1.10.246.60. 1 hit.
KO	K03245.
PANTHER	PTHR21681. eIF3_subunit. 1 hit.
Pfam	PF08597. eIF3_subunit. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EIF3J_DROWI

Accession

Primary (citable) accession number: B4MP81
Secondary accession number(s): Q8I166

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	September 23, 2008
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project