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Protein

Alpha-amylase

Gene

Amyrel

Organism
Drosophila willistoni (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.SAAS annotation

GO - Molecular functioni

  1. catalytic activity Source: InterPro
  2. cation binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseSAAS annotation (EC:3.2.1.1SAAS annotation)
Gene namesi
Name:AmyrelImported
Synonyms:Dwil\AmyrelImported
ORF Names:Dwil_GK10730Imported, GK10730Imported
OrganismiDrosophila willistoni (Fruit fly)Imported
Taxonomic identifieri7260 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007798: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0025016. Dwil\Amyrel.

Interactioni

Protein-protein interaction databases

STRINGi7260.FBpp0239873.

Structurei

3D structure databases

ProteinModelPortaliB4MIU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

InParanoidiB4MIU4.
KOiK01176.
OMAiWDNGDNQ.
PhylomeDBiB4MIU4.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

B4MIU4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLSLSVLLC FGLALTLAQH NPHWWGNRNT IVHLFEWKWT DIADECERFL
60 70 80 90 100
GPRGYAGVQV SPANENIISE GRPWWERYQP ISYKLVTRSG NELEFASMVK
110 120 130 140 150
RCNDVGVRIY VDVLLNHMSA DFDGLATGTG GSVAEPAKKS FPSVPYTADD
160 170 180 190 200
FHETCEITDW NDRFQVQQCE LVGLKDLNQS RDWVRTKLIE FLDHLIELGV
210 220 230 240 250
AGFRVDAAKH MASEDLSFIY SSVRDLNINH GFPNNARPFI YQEVIDHGHE
260 270 280 290 300
TVTREEYNEL GAVTEFRFSE EIGKAFRGNN ALKWLQSWGT DWGFLSSGQA
310 320 330 340 350
LTFVDNHDNQ RDSGDVLNYK SPKQYKMATA FHLAYPYGIS RVMSSFGFDD
360 370 380 390 400
RDQAPPQDAQ EQLISPEFDV DGGCTNGWIC EHRWRQIYNM VEFKNTIRDT
410 420 430 440 450
ELTNWWDNGD NQIAFCRGSK GFIAINNNLS NLSETLQTCL PAGEYCDVIS
460
GSLVNGACTV
Length:460
Mass (Da):52,267
Last modified:September 23, 2008 - v1
Checksum:i301BCE0FF9408F65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH963719 Genomic DNA. Translation: EDW72033.1.
RefSeqiXP_002061047.1. XM_002061011.1.

Genome annotation databases

EnsemblMetazoaiFBtr0241381; FBpp0239873; FBgn0025016.
GeneIDi6637936.
KEGGidwi:Dwil_GK10730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH963719 Genomic DNA. Translation: EDW72033.1.
RefSeqiXP_002061047.1. XM_002061011.1.

3D structure databases

ProteinModelPortaliB4MIU4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7260.FBpp0239873.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0241381; FBpp0239873; FBgn0025016.
GeneIDi6637936.
KEGGidwi:Dwil_GK10730.

Organism-specific databases

FlyBaseiFBgn0025016. Dwil\Amyrel.

Phylogenomic databases

InParanoidiB4MIU4.
KOiK01176.
OMAiWDNGDNQ.
PhylomeDBiB4MIU4.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14030-0811.24Imported.

Entry informationi

Entry nameiB4MIU4_DROWI
AccessioniPrimary (citable) accession number: B4MIU4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 4, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.