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Protein

Angiotensin-converting enzyme

Gene

Dvir\GJ18156

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.003

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dvir\GJ18156Imported
ORF Names:Dvir_GJ18156Imported, GJ18156Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0205321 Dvir\GJ18156

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500281740918 – 615Angiotensin-converting enzymeSequence analysisAdd BLAST598

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0205321

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0232573

Structurei

3D structure databases

ProteinModelPortaliB4M8N1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili18 – 45Sequence analysisAdd BLAST28
Coiled coili55 – 75Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690 Eukaryota
ENOG410XPJ3 LUCA
InParanoidiB4M8N1
KOiK01283
OMAiGPCLPLE
OrthoDBiEOG091G033S
PhylomeDBiB4M8N1

Family and domain databases

CDDicd06461 M2_ACE, 1 hit
InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Complete.

B4M8N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLLVALLA TLALTQALVK EEIQAKEYLE NLNKELAKRT NVETEASWAY
60 70 80 90 100
GSNINDENEK KKNEVSAELA KFMKEVSVDI QKFNWRSYQS DDLKRQFKAL
110 120 130 140 150
SKLGYAALPE ADYAEFLETV SAMESNFAKV KVCDYKNSSK CDLALEPEIE
160 170 180 190 200
EVITKSRDHE ELKYYWTQFY DKAGTAVRPQ FERYVELNTK AAKLNNFTSG
210 220 230 240 250
AELWLDEYED DTFEQQLEDI FSEIRPLYEQ IHGYVRYRLR KHYGDEVVPE
260 270 280 290 300
KGPLPMHLLG NMWAQQWSDI ADLVSPFPDK PLVDVSAEMV KQGYTPLKMF
310 320 330 340 350
QMGDDFFTSM NLTKLPQEFW DKSIIEKPTD GRDLVCHASA WDFYLQNDVR
360 370 380 390 400
IKQCTQVTQS QLFTVHHELG HIQYFLQYQH LPFVYRTGAN PGFHEAVGDV
410 420 430 440 450
LSLSVSTPKH LEKIGLLKDF VLDEEARINQ LFLTALDKIV FLPFAFTMDK
460 470 480 490 500
YRWSLFRGQV DKSNWNCAFW KLREEYSGIE PPVVRSEKDF DAPAKYHVSA
510 520 530 540 550
DVEYLRYLVS FIIQFQFYKS ACVKAGQYDV NNPELPLDNC DIYGSAAAGA
560 570 580 590 600
AFHNMLSLGA SKPWPDALEA FNGERIMTGK AIAEYFEPLR VWLEAENIKN
610
NVPIGWTASD KCVST
Length:615
Mass (Da):70,897
Last modified:September 23, 2008 - v1
Checksum:i05BAE689A72E87D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940654 Genomic DNA Translation: EDW57557.1
RefSeqiXP_002057484.1, XM_002057448.2

Genome annotation databases

EnsemblMetazoaiFBtr0234081; FBpp0232573; FBgn0205321
GeneIDi6633976
KEGGidvi:Dvir_GJ18156

Similar proteinsi

Entry informationi

Entry nameiB4M8N1_DROVI
AccessioniPrimary (citable) accession number: B4M8N1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 31, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported