Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B4M7S0

- PGAM5_DROVI

UniProt

B4M7S0 - PGAM5_DROVI

Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

Pgam5

Organism
Drosophila virilis (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity By similarity.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. phosphoprotein phosphatase activity Source: UniProtKB

    GO - Biological processi

    1. protein dephosphorylation Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase Pgam5, mitochondrialBy similarity (EC:3.1.3.16)
    Alternative name(s):
    Phosphoglycerate mutase family member 5 homologBy similarity
    Gene namesi
    Name:Pgam5By similarity
    ORF Names:GJ17041
    OrganismiDrosophila virilis (Fruit fly)
    Taxonomic identifieri7244 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
    ProteomesiUP000008792: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0204218. Dvir\GJ17041.

    Subcellular locationi

    Mitochondrion outer membrane By similaritySequence Analysis; Single-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial outer membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion outer membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 289289Serine/threonine-protein phosphatase Pgam5, mitochondrialPRO_0000390710Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with Pk92B/ASK1.By similarity

    Protein-protein interaction databases

    STRINGi7244.FBpp0231458.

    Structurei

    3D structure databases

    ProteinModelPortaliB4M7S0.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2317HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG71348.
    InParanoidiB4M7S0.
    KOiK15637.
    OMAiWLRMSLN.
    OrthoDBiEOG7966H1.
    PhylomeDBiB4M7S0.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00300. His_Phos_1. 1 hit.
    [Graphical view]
    SMARTiSM00855. PGAM. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4M7S0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRKFTAFACG TGAGLAAYYL QKLRDPQLAV HNSWTNSDRP ISECALWDSN    50
    WDFRDPKSLV RPQKNDLPQE QNRYNSDLEK HVAKSARHII LIRHGEYLDV 100
    GDSDDTHHLT DRGRLQAKYT GQRLRELGIK WDKVIASNMV RAQETADIIL 150
    NQIDYDKAKL KHCSYLREGA PIPPQPPVGH WKPEASQFFR DGARIEAAFR 200
    RYFHRALPEQ EKESYTLIVG HGNVIRYFVC RALQFPAEAW LRISINHASI 250
    TWLTISPSGN VSIKYLGDTG FMPAKYLTHR IPRDAKNVV 289
    Length:289
    Mass (Da):33,194
    Last modified:September 23, 2008 - v1
    Checksum:iDA3B0488113D26BC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH940653 Genomic DNA. Translation: EDW62837.1.
    RefSeqiXP_002057351.1. XM_002057315.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0232966; FBpp0231458; FBgn0204218.
    GeneIDi6633492.
    KEGGidvi:Dvir_GJ17041.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH940653 Genomic DNA. Translation: EDW62837.1 .
    RefSeqi XP_002057351.1. XM_002057315.1.

    3D structure databases

    ProteinModelPortali B4M7S0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7244.FBpp0231458.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0232966 ; FBpp0231458 ; FBgn0204218 .
    GeneIDi 6633492.
    KEGGi dvi:Dvir_GJ17041.

    Organism-specific databases

    FlyBasei FBgn0204218. Dvir\GJ17041.

    Phylogenomic databases

    eggNOGi NOG71348.
    InParanoidi B4M7S0.
    KOi K15637.
    OMAi WLRMSLN.
    OrthoDBi EOG7966H1.
    PhylomeDBi B4M7S0.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00300. His_Phos_1. 1 hit.
    [Graphical view ]
    SMARTi SM00855. PGAM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15010-1051.87Imported.

    Entry informationi

    Entry nameiPGAM5_DROVI
    AccessioniPrimary (citable) accession number: B4M7S0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 19, 2010
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3