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Protein
Submitted name:

Uncharacterized protein

Gene

Dvir\GJ10771

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Dvir\GJ10771Imported
ORF Names:Dvir_GJ10771Imported, GJ10771Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0198045. Dvir\GJ10771.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0225188.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini374 – 450PWWPInterPro annotationAdd BLAST77
Domaini1014 – 1059PHD-typeInterPro annotationAdd BLAST46
Domaini1064 – 1126PWWPInterPro annotationAdd BLAST63
Domaini1197 – 1247AWSInterPro annotationAdd BLAST51
Domaini1241 – 1366SETInterPro annotationAdd BLAST126
Domaini1374 – 1390Post-SETInterPro annotationAdd BLAST17

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily.SAAS annotation
Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1081. Eukaryota.
COG2940. LUCA.
InParanoidiB4M6G3.
KOiK11424.
OrthoDBiEOG091G02U7.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00249. PHD. 3 hits.
SM00293. PWWP. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4M6G3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSANNTHT EMQDAGVVHT PTEATDNATA GTVVPSVVKT DAGGTLSQLN
60 70 80 90 100
AIQRFPGNLL LRNCINDAES ATDSSEQFTE YEHHNTTDQQ QTPPAARGRH
110 120 130 140 150
RVKTLNRKRD LINLQSNLSP KYIGYPNANS PTVPDSVDKV RTTRRRNHVL
160 170 180 190 200
TPNRDGDSDV ASPKTLLAGM HMLASGAYLS PIDKLLIKNG ANSPNSTGFE
210 220 230 240 250
ADAEDVAMMQ PTRKQLKRKL KRDSKPKKKH PKETPAEVTA KETSDHLTKD
260 270 280 290 300
EQSHQKQAIF KIGQTLATDK PEISIKVELT EEDAPHKIFE ADEQIHVKTE
310 320 330 340 350
LKTAEQKDIE GGQVDSILAL PTATSTEMEA LKSPPDIEPA NNSEQSMKSP
360 370 380 390 400
SSISLDSAKG SSIVTDSGWP TYQVGDLYWG KLFTYCYWPC MVCPDQLGQI
410 420 430 440 450
VGNPHTHPQR KSTDSAPGAP VPIQVHVRFF ADNGRHNWIK SENLLPFAGL
460 470 480 490 500
KAFEELREEA RIKYGPRSLK YRQMTAKQNK QIVWRQAIEE ANIVGQLPYA
510 520 530 540 550
ERMQKFYEIY ENTVIHNKEK RKYTKSVRQD TSDVGSSLYD STDNLLAKTQ
560 570 580 590 600
HAQPLKRERS SSPFSPAFSP VKHNHQKRAK RRKLSGSLEA PVGYTPLSEP
610 620 630 640 650
HGEKLVSPDL VNYKNPEFGQ LFDAIKEYVM VHRQEEKVEK VLLAVVRNIW
660 670 680 690 700
SLKQLQLREL ERDLASGESE LLGSARLGSE RGRGVGTIKR LSNRLKTMML
710 720 730 740 750
RRSITPVVTP STAAPAQIST PESMQTERHL SENPKVRKPI GRPIDEVIED
760 770 780 790 800
ILQLDRKYLF RGLNREPVCK YCYEPGGDIQ RCSLNCNSWL HATCLDQQIT
810 820 830 840 850
VNTKAKKGLK AVGPAPSKPP EPLTSSSPVS EVEPTTTTST LTKHITGDEI
860 870 880 890 900
KQEQNKEPLV CHECASGKSN ACCICHQEQL PVNSPPPSPH KESVASATAI
910 920 930 940 950
SEVEEPPISN KLILCCQPMC SNKFHASCCK YWPQASISNS STRCPMHVCH
960 970 980 990 1000
TCVSDDPSGK YQQLGSAKLT KCVKCPATYH QDSRCIPAGS RMLTVTHLIC
1010 1020 1030 1040 1050
PRHNIAKADA NLNVLWCYIC VRGGELVCCE TCPIAVHAHC RNIPIKTNES
1060 1070 1080 1090 1100
YICEECESGR LPLYGEIVWA KFNNFRWWPS IILPPTEIPS NILKKPHGAN
1110 1120 1130 1140 1150
DFVVRFFGTN DHGWISRRRV YLYIEGDTGD GYKSKSLMSK RYTAGVEEAT
1160 1170 1180 1190 1200
RFLKIIKDKR QEQAIGRFSG NKLYPPPYIK IKANKPVPPV RFVYNEEDLN
1210 1220 1230 1240 1250
ICECKPGSEH PCGPESGCLN RMLYHECHPD YCHAGRQCEN QLFELRKSPR
1260 1270 1280 1290 1300
LEVVYMNERG FGLVCREPIA EGDFIIEYVG EVINHAEFQR RMAQKTRDRD
1310 1320 1330 1340 1350
ENFYFLGVEK DFIIDAGPKG NLARFMNHSC EPNCATQKWT VNCINRVGLF
1360 1370 1380 1390 1400
AIKDIPENTE LTFNYLWDDL MNNGKKACFC GAKRCSGEIG GKLKDEEVKE
1410 1420 1430 1440 1450
TKIKQLPRHK GIRIHVGAPK KKAAKRSKSK HMGADNVPPT EQPLDAAPAS

KEP
Length:1,453
Mass (Da):162,777
Last modified:January 20, 2016 - v2
Checksum:iE56E877E530CF62A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940652 Genomic DNA. Translation: EDW59239.2.
RefSeqiXP_002056127.2. XM_002056091.2.

Genome annotation databases

EnsemblMetazoaiFBtr0226696; FBpp0225188; FBgn0198045.
GeneIDi6632940.
KEGGidvi:Dvir_GJ10771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940652 Genomic DNA. Translation: EDW59239.2.
RefSeqiXP_002056127.2. XM_002056091.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7244.FBpp0225188.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0226696; FBpp0225188; FBgn0198045.
GeneIDi6632940.
KEGGidvi:Dvir_GJ10771.

Organism-specific databases

FlyBaseiFBgn0198045. Dvir\GJ10771.

Phylogenomic databases

eggNOGiKOG1081. Eukaryota.
COG2940. LUCA.
InParanoidiB4M6G3.
KOiK11424.
OrthoDBiEOG091G02U7.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00249. PHD. 3 hits.
SM00293. PWWP. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4M6G3_DROVI
AccessioniPrimary (citable) accession number: B4M6G3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: January 20, 2016
Last modified: November 30, 2016
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.