B4M5T5 (PTC71_DROVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein phosphatase PTC7 homolog fig

Alternative name(s):
Fos intronic gene protein
EC=3.1.3.16

Gene names

Name:	fig
ORF Names:	GJ10517

Organism

Drosophila virilis (Fruit fly) [Complete proteome]

Taxonomic identifier

7244 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Drosophila › virilis group

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate. UniProtKB P35813
Cofactor	Magnesium or manganese Potential. UniProtKB P35813
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 313	313	Protein phosphatase PTC7 homolog fig		PRO_0000377404
Regions
	Domain	42 – 305	264	PP2C-like
Sites
	Metal binding	83	1	Manganese 1 By similarity UniProtKB P35813
	Metal binding	83	1	Manganese 2 By similarity UniProtKB P35813
	Metal binding	84	1	Manganese 1; via carbonyl oxygen By similarity UniProtKB P35813
	Metal binding	229	1	Manganese 2 By similarity UniProtKB P35813

Sequences

	Sequence		Length	Mass (Da)
	B4M5T5 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: F51FC723A8C3CCB7	FASTA	313	34,263
	10 20 30 40 50 60 MFFTVRTLSN RTSHVLNCAF AQCRLLSSTA SAKGVPRLIK AIQGSSKEPL TDLQLRLIGD 70 80 90 100 110 120 NRYGEDSWFV SSTPKAETMG VADGVGGWRK LGIDAGVFAR ELMSHCSEFA EQAEYDGLNP 130 140 150 160 170 180 RQLLIDSYDR LKNKRPCNVC GSSTACLVTL HRPDCTLHSA NLGDSGFLVL RNGRVLHRSD 190 200 210 220 230 240 EQLHCFNTPY QLTVPPHPAM DCVLRDSPEQ AVSTHLPLQP GDLVLLATDG LFDNVPESML 250 260 270 280 290 300 INQLRALQGE TRAEYLQQAA NRLVDLAKTL SVSPTFQSPF ALKARANNVD YGIGGKPDDI 310 TVILASLEVP DKL

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tucson 15010-1051.87.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH940652 Genomic DNA. Translation: EDW59011.1.
RefSeq	XP_002055899.1. XM_002055863.1.
3D structure databases
ProteinModelPortal	B4M5T5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0226442; FBpp0224934; FBgn0197797.
GeneID	6632264.
KEGG	dvi:Dvir_GJ10517.
Organism-specific databases
FlyBase	FBgn0197797. Dvir\GJ10517.
Phylogenomic databases
eggNOG	COG0631.
InParanoid	B4M5T5.
OMA	GEDSWFV.
OrthoDB	EOG4ZKH2X.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. [Graphical view]
Pfam	PF07228. SpoIIE. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTC71_DROVI

Accession

Primary (citable) accession number: B4M5T5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2009
Last sequence update:	September 23, 2008
Last modified:	March 6, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project