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B4M5T5

- PTC71_DROVI

UniProt

B4M5T5 - PTC71_DROVI

Protein

Protein phosphatase PTC7 homolog fig

Gene

fig

Organism
Drosophila virilis (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Magnesium or manganese.By similarityCurated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi83 – 831Manganese 1By similarity
    Metal bindingi83 – 831Manganese 2By similarity
    Metal bindingi84 – 841Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi229 – 2291Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: UniProtKB

    GO - Biological processi

    1. dephosphorylation Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase PTC7 homolog fig
    Alternative name(s):
    Fos intronic gene protein (EC:3.1.3.16)
    Gene namesi
    Name:figBy similarity
    ORF Names:GJ10517
    OrganismiDrosophila virilis (Fruit fly)
    Taxonomic identifieri7244 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
    ProteomesiUP000008792: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0197797. Dvir\GJ10517.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 313313Protein phosphatase PTC7 homolog figPRO_0000377404Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi7244.FBpp0224934.

    Structurei

    3D structure databases

    ProteinModelPortaliB4M5T5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini42 – 305264PP2C-likeSequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Sequence Analysis
    Contains 1 PP2C-like domain.Sequence Analysis

    Phylogenomic databases

    eggNOGiCOG0631.
    InParanoidiB4M5T5.
    KOiK17508.
    OMAiFITISHH.
    OrthoDBiEOG7DRJ3F.
    PhylomeDBiB4M5T5.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    [Graphical view]
    PfamiPF07228. SpoIIE. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4M5T5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFFTVRTLSN RTSHVLNCAF AQCRLLSSTA SAKGVPRLIK AIQGSSKEPL    50
    TDLQLRLIGD NRYGEDSWFV SSTPKAETMG VADGVGGWRK LGIDAGVFAR 100
    ELMSHCSEFA EQAEYDGLNP RQLLIDSYDR LKNKRPCNVC GSSTACLVTL 150
    HRPDCTLHSA NLGDSGFLVL RNGRVLHRSD EQLHCFNTPY QLTVPPHPAM 200
    DCVLRDSPEQ AVSTHLPLQP GDLVLLATDG LFDNVPESML INQLRALQGE 250
    TRAEYLQQAA NRLVDLAKTL SVSPTFQSPF ALKARANNVD YGIGGKPDDI 300
    TVILASLEVP DKL 313
    Length:313
    Mass (Da):34,263
    Last modified:September 23, 2008 - v1
    Checksum:iF51FC723A8C3CCB7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH940652 Genomic DNA. Translation: EDW59011.1.
    RefSeqiXP_002055899.1. XM_002055863.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0226442; FBpp0224934; FBgn0197797.
    GeneIDi6632264.
    KEGGidvi:Dvir_GJ10517.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH940652 Genomic DNA. Translation: EDW59011.1 .
    RefSeqi XP_002055899.1. XM_002055863.1.

    3D structure databases

    ProteinModelPortali B4M5T5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7244.FBpp0224934.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0226442 ; FBpp0224934 ; FBgn0197797 .
    GeneIDi 6632264.
    KEGGi dvi:Dvir_GJ10517.

    Organism-specific databases

    FlyBasei FBgn0197797. Dvir\GJ10517.

    Phylogenomic databases

    eggNOGi COG0631.
    InParanoidi B4M5T5.
    KOi K17508.
    OMAi FITISHH.
    OrthoDBi EOG7DRJ3F.
    PhylomeDBi B4M5T5.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    [Graphical view ]
    Pfami PF07228. SpoIIE. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15010-1051.87Imported.

    Entry informationi

    Entry nameiPTC71_DROVI
    AccessioniPrimary (citable) accession number: B4M5T5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3