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Protein

Hexokinase

Gene

Dvir\GJ19157

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:Dvir\GJ19157Imported
ORF Names:Dvir_GJ19157Imported, GJ19157Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000008792: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0206302. Dvir\GJ19157.

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0233574.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB4M364.
KOiK00844.
OMAiKIVVKVC.
OrthoDBiEOG7S21X5.
PhylomeDBiB4M364.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4M364-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQEQLNGAM RSVSINSNGL ATNQNGHNGN DETDNARVLG GGGGGGGISF
60 70 80 90 100
GLSSGNAASK ATNAATNAAT NAATNAATDA ATATETATAT ANANVNAIQI
110 120 130 140 150
QTSAAGASAA DKKKMVHELC QQLLLTDEQV QELCYRILHE VRRGLAKDTH
160 170 180 190 200
PKANVKCFVT YVQDLPNGNE RGKFLALDLG GTNFRVLLIH LQENNDFQME
210 220 230 240 250
SRIYAIPQHI MIGSGLQLFD HIAECLSNFM AEHNVYSERL PLGFTFSFPL
260 270 280 290 300
RQLGLTKGLL ETWTKGFDCA GVVNEDVVQL LKDAIARRGD VQIDVCAILN
310 320 330 340 350
DTTGTLMSCA WKNHNCKIGL IVGTGSNACY VEKVDEAELF DMRDNRKPHV
360 370 380 390 400
LINTEWGAFG DNGALDFVRT EFDKDIDSHS INPGKQTFEK MISGMYMGEL
410 420 430 440 450
VRLVLAKMTQ AGILFNGQGS EVLFTRGLFF TKYVSEIEAD EPGTYTNCRL
460 470 480 490 500
VLEELGLSNA TDGDCANVRY ICECVSKRAA HLVSAGIATL INKMDEPHVT
510 520 530 540 550
VGVDGSVYRF HPKFHNLMVE KITQLIKPGI SFDLMLSEDG SGRGAALVAA
560
VACREDILNS K
Length:561
Mass (Da):60,643
Last modified:September 23, 2008 - v1
Checksum:i1D84FC22800C1AC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940651 Genomic DNA. Translation: EDW65239.1.
RefSeqiXP_002055038.1. XM_002055002.1.

Genome annotation databases

EnsemblMetazoaiFBtr0235082; FBpp0233574; FBgn0206302.
GeneIDi6631573.
KEGGidvi:Dvir_GJ19157.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940651 Genomic DNA. Translation: EDW65239.1.
RefSeqiXP_002055038.1. XM_002055002.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7244.FBpp0233574.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0235082; FBpp0233574; FBgn0206302.
GeneIDi6631573.
KEGGidvi:Dvir_GJ19157.

Organism-specific databases

FlyBaseiFBgn0206302. Dvir\GJ19157.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB4M364.
KOiK00844.
OMAiKIVVKVC.
OrthoDBiEOG7S21X5.
PhylomeDBiB4M364.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15010-1051.87Imported.

Entry informationi

Entry nameiB4M364_DROVI
AccessioniPrimary (citable) accession number: B4M364
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.