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Protein

Delta-like protein

Gene

Dvir\GJ23176

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Putative Notch ligand involved in the mediation of Notch signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Delta-like proteinUniRule annotation
Gene namesi
Name:Dvir\GJ23176Imported
ORF Names:Dvir_GJ23176Imported, GJ23176Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0210278. Dvir\GJ23176.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1219 – 1242HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0237593.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini244 – 288DSLInterPro annotationAdd BLAST45
Domaini289 – 322EGF-likeInterPro annotationAdd BLAST34
Domaini356 – 394EGF-likeInterPro annotationAdd BLAST39
Domaini450 – 491EGF-likeInterPro annotationAdd BLAST42
Domaini493 – 529EGF-likeInterPro annotationAdd BLAST37
Domaini578 – 614EGF-likeInterPro annotationAdd BLAST37
Domaini616 – 651EGF-likeInterPro annotationAdd BLAST36
Domaini653 – 689EGF-likeInterPro annotationAdd BLAST37
Domaini691 – 726EGF-likeInterPro annotationAdd BLAST36
Domaini753 – 790EGF-likeInterPro annotationAdd BLAST38
Domaini792 – 828EGF-likeInterPro annotationAdd BLAST37
Domaini830 – 870EGF-likeInterPro annotationAdd BLAST41
Domaini872 – 908EGF-likeInterPro annotationAdd BLAST37
Domaini910 – 946EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
InParanoidiB4M0A6.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB4M0A6.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 7 hits.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4M0A6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKMFRKHFR RKSTKGNTAT TTATTATTAT ETTTGSLRMS ATRQRQRQRQ
60 70 80 90 100
RPRQTTALRS LIDDCRSLKS ACNLIALILI LLVHKISAAG NFELEILEIS
110 120 130 140 150
NTNSHLLSGY CCGVPTELRA TKTTGCSPCT TAFRLCLKEY QTTEQGVSIS
160 170 180 190 200
TGCSFGNSTT KILGGSSFVL SDPGVGAIVL PFTFRWTKSF TLILQALDMY
210 220 230 240 250
NTSYPDAERL IEETSYSGVI LPSPEWKTLD HIGRNARITY RVRVQCAVTY
260 270 280 290 300
YNTTCTTFCR PRDDQFGHYA CGSEGQKLCL NGWQGVNCEE AICKPGCDPI
310 320 330 340 350
HGKCDRPGEC ECRPGWRGPL CNECMVYPGC KHGSCNGSAW KCVCDTNWGG
360 370 380 390 400
ILCDQDLNYC GTHEPCKHGG TCENTAPDQY RCTCAEGLSG EQCEIVEHPC
410 420 430 440 450
ATQPCRNGGT CTLKLTNATR PPTYRVMRGM SSSMGKPISR RNSIRSLAGL
460 470 480 490 500
FQESQNASGN GSQQQQQQQL PPLAAEFTCG CVAGWTGPTC EINIDECAGG
510 520 530 540 550
PCEHGGTCVD LIGGFRCECP PEWRGDVCQV DVNECEASYA AALPANTLLT
560 570 580 590 600
TTASAIIASN LSSSAALLAA LTSAVAASSS AATHGPCINA RECLNLPGSF
610 620 630 640 650
SCLCLEGWGG ATCAENLDDC VGQCKNGASC IDLVNDYRCA CSAGYTGRDC
660 670 680 690 700
ETDIDECANS PCRNGGECVD MVGKFNCICP LGYSGTLCEE AKDHCTPSPC
710 720 730 740 750
LQGRCLNTPG SYYCHCPPDR AGKHCEQLRP LCSQPPCNEG CFANVSATAK
760 770 780 790 800
PTTSTTTAGG QPCSGHGSCE MSDVGTFCKC HVGHTGTFCE HNLNECSPNP
810 820 830 840 850
CRNGGICLDG DGDFTCECMS GWTGKRCSER ATVCYAGQCQ NGGTCMPGAP
860 870 880 890 900
DKALQPHCRC APGWTGLFCA EAIDQCRGQP CHNGGTCESG AGWFRCLCAQ
910 920 930 940 950
GFSGPDCRIN VNECSPQPCQ GGATCIDGIG GYTCICPPGR HGLRCEILLS
960 970 980 990 1000
DPKSACLNAT NTISPYAALN QSQNWLDIAL TGRSDEDEHC NACVCENATS
1010 1020 1030 1040 1050
RCTNLWCGLA NCFKLDPLSK SSNLSGVCKQ HEVCVPALGE TCLSPPCSVR
1060 1070 1080 1090 1100
GDCRALEPSR RVAPPRLPAK ASCWPNQALV NENCARLTIL LDLERVGKGA
1110 1120 1130 1140 1150
TVEGLCSLVR VLLAARLIKQ PLTPQTSPAQ EEGMLMVLCD LKTGTNDTIE
1160 1170 1180 1190 1200
LTVSSSKLND QQLPVAVSLL GELLSSRQLN GIQRRNELQL QHAKLAALTS
1210 1220 1230 1240 1250
ILEVKLETAR VADGNSHSLL IGVLCGIFIV LVGFSVFISL YWKQRLAYRS
1260 1270 1280 1290 1300
SSGMNLTPPL DALRHEEEKS NNLQNEENLR RYTNPLKGST SSLRAGTGME
1310 1320 1330 1340 1350
LSLNPAPELA ASAASSSALH RSQPLFPPCD FERELDASTG LKQAHKRSSQ
1360 1370 1380 1390 1400
ILLHKTQNSD MKKNTVGSLE SPRKDFGKRS INCKSLPPQA SDESGDVLAT

VVV
Length:1,403
Mass (Da):150,369
Last modified:September 23, 2008 - v1
Checksum:iE843ECFAAD623E63
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940650 Genomic DNA. Translation: EDW67268.1.
RefSeqiXP_002053748.1. XM_002053712.2.

Genome annotation databases

EnsemblMetazoaiFBtr0239101; FBpp0237593; FBgn0210278.
GeneIDi6630619.
KEGGidvi:Dvir_GJ23176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940650 Genomic DNA. Translation: EDW67268.1.
RefSeqiXP_002053748.1. XM_002053712.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7244.FBpp0237593.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0239101; FBpp0237593; FBgn0210278.
GeneIDi6630619.
KEGGidvi:Dvir_GJ23176.

Organism-specific databases

FlyBaseiFBgn0210278. Dvir\GJ23176.

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
InParanoidiB4M0A6.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB4M0A6.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 7 hits.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4M0A6_DROVI
AccessioniPrimary (citable) accession number: B4M0A6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 30, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.