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B4M059

- B4M059_DROVI

UniProt

B4M059 - B4M059_DROVI

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Protein
Submitted name:

Trx

Gene
trx, Dvir\trx, Dvir_GJ22599, GJ22599
Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. histone methyltransferase activity (H3-K4 specific) Source: InterPro
  2. sequence-specific DNA binding Source: InterPro
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotations, Transferase

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotations

Keywords - Ligandi

DNA-bindingSAAS annotations, Metal-binding, S-adenosyl-L-methionineSAAS annotations, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
TrxImported
Gene namesi
Name:trxImported
Synonyms:Dvir\trxImported
ORF Names:Dvir_GJ22599Imported, GJ22599Imported
OrganismiDrosophila virilis (Fruit fly)
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000008792: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0014844. Dvir\trx.

Subcellular locationi

GO - Cellular componenti

  1. histone methyltransferase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0237016.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.
Contains 1 post-SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains nuclear receptor DNA-binding domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Keywords - Domaini

Zinc-fingerSAAS annotations

Phylogenomic databases

KOiK09186.
OMAiARCEPYS.
PhylomeDBiB4M059.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR016569. MeTrfase_trithorax.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR011011. Znf_FYVE_PHD.
IPR001628. Znf_hrmn_rcpt.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PIRSFiPIRSF010354. Methyltransferase_trithorax. 1 hit.
SMARTiSM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00184. RING. 4 hits.
SM00317. SET. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 2 hits.
PROSITEiPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4M059-1 [UniParc]FASTAAdd to Basket

« Hide

MGRSKFPGKP SKSINRKRIS VLQLEDEAAS AAAAAATAAT TEQHQQSEQS     50
AGSSASREKG NNCDNDDDDN APSGAATSGN RGASSGASDA AATEGGNSTG 100
NGSSTGGKTT NGGNVNGGSH HKSATAPAEL KECKNQGNQI EPNNCIAAEP 150
DGTEDTNNDD DDDSSNDKKP TAAAAAAAAA AFVPGPSALQ RARKGGNKKF 200
KNLNLARPEV MLPSTSKLKQ QQQQQLQLNC PSASASSLSS SAAAAAAAAA 250
PTTTTTTASA SATLTATATS TSTSSLPGTP LSVIAGGGGG AAAAGLLLAN 300
PFASVETKVV EVNAAATAAA GAGEDVAMLH ALLIGQEASS GTFMTYLTFM 350
FLQLKASIEM ANEAGLEAPA VAVKSSGSSP NPNHNPNAVA GSTSAAAPGA 400
PTATKQKKTV TFKNILETSD DKSVVKRFYN PDNRVPLVSI MKKDSLNRPL 450
NYCRGSEFIV RPSILSKILN KNSNIDKLNS LKFRSVHASS NSIQESSSST 500
TNLFGSGLSR AFGAPIDDED AVSGGVTFRK QEPQHKTPED NDDDGSASSD 550
AIEDDEDIDD DDAEDNEEAA SEKSAETTAS VDEKEADDRQ LVMDKHFVLP 600
KRSTRSSRII KPNKRLLEVG GICSKRSPSD ANGKPKPKNY FGLGDFASEV 650
HASSSSSSST SAATALSQKL GKETFTSFAT AKVNSSFVLR QPRLQFQTDK 700
SGSFVSAKPT LPTTTLLPAS SSAITSANVL SFGALNNANS AVAAASTCAV 750
CSAPVNNKDA PLARKYGVIA CEVCRKFNSR MTKISKLSTP MHSNPSTSTA 800
QSGQQLKCTD GGNCSILSLK SQLKNFKKLY KERCKACWLK KCLATLQLPA 850
GHRSRLSAIL PASMREEVAP KDDKCPELLS PTASLRFTAP TSSASSGTTI 900
KWKSSAETAV NSIKSNPLAE NNVTFGGTPL LRPAILEKPL FLKIGSDNKK 950
AKESKEALGL SPVPSTSEAA VAPGKTTRKA KQDKEKAREQ EAEKPLSPNA 1000
KKTTEANTPE TQKDEQPAST TTTVSAASSS TPHTSSAATN SSQLETTEAA 1050
NASTVPDNLK RQRIDLKGPR VKHVCRSASI VLGQPLATFG DEEEELAAAE 1100
AGPAPTTTTT TTSPEVIIKK PKSPQPMQMI IDENDNCASC ILTPTEAPAE 1150
AQPAVKSVLE SKSSKSNTQT EAKKTPATSG SSKGKVTTRN ATATVTSVAS 1200
SLVATKKQRN IEVSSSISSS QAAATQSRRA LAKEVNRLKA LISIDFWENY 1250
DPAEVCQTGF GLIVTETVAQ RALCFLCGST GLDPLIFCAC CCEPYHQYCV 1300
LDEYNLKHSS FEDTLMNSLL ETSNNACAIS AATNTALNQL TQRLNWLCPR 1350
CTVCYTCNMS SGSKVKCQKC QKNYHSTCLG TSKRLLGADR PLICVNCLKC 1400
KSCATTKVSK FVGNLPMCTA CFKLRKKGNF CPICQKCYDD NDFDLKMMEC 1450
GDCNQWVHSK CEGLSDEQYN LLSTLPESIE FICKKCARRC DVSRNKADEW 1500
RQAVMEEFKS SLYSVLKLLS KSRQACALLK LSPRKKLRCS CSAGGAAGKA 1550
HSQGKLQPKA LQFTYNGLGS DGESQNSDDI YEFKEQHSTN RKPSTPVPCS 1600
CLQPLSQSPS FSLVDIKQKI ASNAYVSLAE FNYDMSQVIQ QSNCDELDIA 1650
YKELLSEQFP WFQNETKACT DALEEDMFES CGYEELEESP TTYAEHHTAS 1700
QAPRTGLLDI PLDDVDDLGG CAVKTRLDTR VCLFCRKSGE GLSGEEARLL 1750
YCGHDCWVHI NCAMWSAEVF EEIDGSLQNV HSAVARGRMI KCTVCGNRGA 1800
TVGCNVKSCG EHYHYPCARS IDCAFLTDKS MYCPAHARNA LKANGSPSVT 1850
YESNFEVSRP VYVELDRKRK KLIEPAKVQF HIGSLEVRQL GSIVPRFSDS 1900
FEAIVPINFL CSRLYWSSKE PWKIVEYTVR TTIQNSYSSS LTLDAGRNFT 1950
VDHTNPNCSL VQLGLAQIAR WHSSLARSDL LDTDWAEFPN SYVPADENTE 2000
EEPQQNADLL PPEIKDAIFE DLPHELLDGI SMLDIFMYED LGDKTELFAM 2050
SEQSKDGTTA TSQTGGGSVS ICDEDTRNSN SLSKQLELSN CWPASNPVED 2100
AMLCAARSSS QAKQRGEVLK KTATAPTRSW PKLDGGSVAA FKRRKLSKNI 2150
AEGVLLSLNQ RSKKEMATVA GITRRQSVCG SSELPPEGSA TMRTKSFTWS 2200
AAKCLFEKNE SREEPAKLKI MQMDGVDDSI TEYRIIGSDG NLSTAQFTGQ 2250
VKCERCQCTY RNYDSFQRHL GSCEPMSTSE SESETATGTA QLSAESLNEL 2300
QKQALAAATL SNTGGLNYLQ TSFPQVQNLA TLGQFGVQGL QGLQTLQLQP 2350
QSLGNGFFLS QPNAAQATSN GNDELQLYAN SLQNLAANLG GGFTLTQPTM 2400
STQAQPQLIA LSTNPDGTQQ FIQLPQSNGA TTQLLQTAAP AAMPTATYQT 2450
LQATNSDKKI VLPLRNAGKP LKTVATKAAQ QATAAAKQKQ LKSAHGVKPI 2500
QAKLQPQQQQ QQHQQHQQQQ HQQQQQQQQQ QQQQQTPITV AQHGGTTQLL 2550
GQNLLQPQLL FQSNAQPQTQ QLLLPQTQAQ NIISFVTGDG SQNQPLQYIS 2600
IPTTNDFKPQ QTTSTPTFLT APGGGATFLQ TDASGNLMLT TAPANSGLQM 2650
LTGQLQTQPQ VIGTLIQPQT LQLTTGADGT QSATAQQPLI LGGATGGGTT 2700
GLEFATATPQ VILATQPMYY GLETIVQNTV MSSQQFVSTA MPGVLSQNSS 2750
FSATTTQVFQ ASKIEPIVDL PAGYVVLNNA VDASGNTSWL QQSQTQATDD 2800
ATAQLLQNAG FQFQTTPTTS TQQTMSTDYA PPLVVTAKVP PVAQMKRNTN 2850
ANKSPISVLS KVQPQPQQSQ VVNKVLPTNL TSQFQRQQQA NELKNKQAAG 2900
QQTGSTCGAP PSIASKPLQK KTNLIRPIHK VEVKPKIMKQ APKLATSAAS 2950
MQHHQQQQSP AAINQVAKVA LLQQRLPPAP QPQQQQPQQQ QQQLHQQQQQ 3000
QQQQQQHMQQ HQQQQQQLSM PQLLPAQQPI ISIVNTAEPQ AATQFVITPA 3050
LQAQAQPIQL QEQQSQQQQQ QPAEQLINGN ATRLQHYASN SLPTNVVNPL 3100
QQQPLAASAN NSSNSNVTQQ NSTITINSRP TNRVLPMQQR QEPTPLSNDV 3150
VVQSPTPPKP IEEPVPAGAS TQKPIVKCYA QLEQKSPGYE TELKTNITLD 3200
NLEQTNSITT LQLQQPQQGP IYGEQIFEKQ SEAQVQLEKP KHNDLMLLEA 3250
TSCQQQQQQQ QQHMEMVVDN GFQLTSNESC LLEKHGFNVE AVPMDTEDHY 3300
ASMKNGSGGG AAEGIGQVDD AEEDEDDDDD FSLKMATSAC NDHEMSDSEE 3350
PAVKEKISKI LDNLTNDDCA DSITTATTVE ASAGYQQMVE DVLATTAAGS 3400
VSTDDETFTA TAEAVEAAAS YINEMAEAHE LQLKQLQAGV ELDLKKPKLD 3450
VPQQQPNTVP TNVVPTAAAP QQPPPMRDPK KISGPHLLYE IQSEDGFTYK 3500
SSSIAEIWEK VFEAVQVARR AHGLTPLPEG PLADMSGVQM IGLKTNALKY 3550
LIEQLPGVEK CVKYTPKYHK RNGNVSTAAG GGHAASTAGS NAAALGAGAD 3600
AQALIDYGSD QEELQENAYE CARCEPYVSR SEYDMFSWLA SRHRKQPIQV 3650
FVQPSDNELV PRRGTGSNLP MAMKYRTLKE TYKDYVGVFR SHIHGRGLYC 3700
TKDIEAGEMV IEYAGELIRS TLTDKRERYY DSRGIGCYMF KIDDNLVVDA 3750
TMRGNAARFI NHSCEPNCYS KVVDILGHKH IIIFALRRIV QGEELTYDYK 3800
FPFEDEKIPC SCGSKRCRKY LN 3822
Length:3,822
Mass (Da):412,089
Last modified:September 23, 2008 - v1
Checksum:iFFF3F8E8E459DBAF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH940650 Genomic DNA. Translation: EDW68309.1.
RefSeqiXP_002054789.1. XM_002054753.1.

Genome annotation databases

EnsemblMetazoaiFBtr0238524; FBpp0237016; FBgn0014844.
GeneIDi6630169.
KEGGidvi:Dvir_GJ22599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH940650 Genomic DNA. Translation: EDW68309.1 .
RefSeqi XP_002054789.1. XM_002054753.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7244.FBpp0237016.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0238524 ; FBpp0237016 ; FBgn0014844 .
GeneIDi 6630169.
KEGGi dvi:Dvir_GJ22599.

Organism-specific databases

FlyBasei FBgn0014844. Dvir\trx.

Phylogenomic databases

KOi K09186.
OMAi ARCEPYS.
PhylomeDBi B4M059.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
InterProi IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR016569. MeTrfase_trithorax.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR011011. Znf_FYVE_PHD.
IPR001628. Znf_hrmn_rcpt.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
PIRSFi PIRSF010354. Methyltransferase_trithorax. 1 hit.
SMARTi SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00184. RING. 4 hits.
SM00317. SET. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 2 hits.
PROSITEi PS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15010-1051.87.

Entry informationi

Entry nameiB4M059_DROVI
AccessioniPrimary (citable) accession number: B4M059
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi