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B4M059 (B4M059_DROVI) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length3822 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214

Sequence similarities

Contains 1 SET domain.

Contains 1 post-SET domain. RuleBase RU004541

Contains SET domain. SAAS SAAS001214

Contains nuclear receptor DNA-binding domain. SAAS SAAS001628

Contains post-SET domain. SAAS SAAS001214

Sequences

Sequence LengthMass (Da)Tools
B4M059 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: FFF3F8E8E459DBAF

FASTA3,822412,089
        10         20         30         40         50         60 
MGRSKFPGKP SKSINRKRIS VLQLEDEAAS AAAAAATAAT TEQHQQSEQS AGSSASREKG 

        70         80         90        100        110        120 
NNCDNDDDDN APSGAATSGN RGASSGASDA AATEGGNSTG NGSSTGGKTT NGGNVNGGSH 

       130        140        150        160        170        180 
HKSATAPAEL KECKNQGNQI EPNNCIAAEP DGTEDTNNDD DDDSSNDKKP TAAAAAAAAA 

       190        200        210        220        230        240 
AFVPGPSALQ RARKGGNKKF KNLNLARPEV MLPSTSKLKQ QQQQQLQLNC PSASASSLSS 

       250        260        270        280        290        300 
SAAAAAAAAA PTTTTTTASA SATLTATATS TSTSSLPGTP LSVIAGGGGG AAAAGLLLAN 

       310        320        330        340        350        360 
PFASVETKVV EVNAAATAAA GAGEDVAMLH ALLIGQEASS GTFMTYLTFM FLQLKASIEM 

       370        380        390        400        410        420 
ANEAGLEAPA VAVKSSGSSP NPNHNPNAVA GSTSAAAPGA PTATKQKKTV TFKNILETSD 

       430        440        450        460        470        480 
DKSVVKRFYN PDNRVPLVSI MKKDSLNRPL NYCRGSEFIV RPSILSKILN KNSNIDKLNS 

       490        500        510        520        530        540 
LKFRSVHASS NSIQESSSST TNLFGSGLSR AFGAPIDDED AVSGGVTFRK QEPQHKTPED 

       550        560        570        580        590        600 
NDDDGSASSD AIEDDEDIDD DDAEDNEEAA SEKSAETTAS VDEKEADDRQ LVMDKHFVLP 

       610        620        630        640        650        660 
KRSTRSSRII KPNKRLLEVG GICSKRSPSD ANGKPKPKNY FGLGDFASEV HASSSSSSST 

       670        680        690        700        710        720 
SAATALSQKL GKETFTSFAT AKVNSSFVLR QPRLQFQTDK SGSFVSAKPT LPTTTLLPAS 

       730        740        750        760        770        780 
SSAITSANVL SFGALNNANS AVAAASTCAV CSAPVNNKDA PLARKYGVIA CEVCRKFNSR 

       790        800        810        820        830        840 
MTKISKLSTP MHSNPSTSTA QSGQQLKCTD GGNCSILSLK SQLKNFKKLY KERCKACWLK 

       850        860        870        880        890        900 
KCLATLQLPA GHRSRLSAIL PASMREEVAP KDDKCPELLS PTASLRFTAP TSSASSGTTI 

       910        920        930        940        950        960 
KWKSSAETAV NSIKSNPLAE NNVTFGGTPL LRPAILEKPL FLKIGSDNKK AKESKEALGL 

       970        980        990       1000       1010       1020 
SPVPSTSEAA VAPGKTTRKA KQDKEKAREQ EAEKPLSPNA KKTTEANTPE TQKDEQPAST 

      1030       1040       1050       1060       1070       1080 
TTTVSAASSS TPHTSSAATN SSQLETTEAA NASTVPDNLK RQRIDLKGPR VKHVCRSASI 

      1090       1100       1110       1120       1130       1140 
VLGQPLATFG DEEEELAAAE AGPAPTTTTT TTSPEVIIKK PKSPQPMQMI IDENDNCASC 

      1150       1160       1170       1180       1190       1200 
ILTPTEAPAE AQPAVKSVLE SKSSKSNTQT EAKKTPATSG SSKGKVTTRN ATATVTSVAS 

      1210       1220       1230       1240       1250       1260 
SLVATKKQRN IEVSSSISSS QAAATQSRRA LAKEVNRLKA LISIDFWENY DPAEVCQTGF 

      1270       1280       1290       1300       1310       1320 
GLIVTETVAQ RALCFLCGST GLDPLIFCAC CCEPYHQYCV LDEYNLKHSS FEDTLMNSLL 

      1330       1340       1350       1360       1370       1380 
ETSNNACAIS AATNTALNQL TQRLNWLCPR CTVCYTCNMS SGSKVKCQKC QKNYHSTCLG 

      1390       1400       1410       1420       1430       1440 
TSKRLLGADR PLICVNCLKC KSCATTKVSK FVGNLPMCTA CFKLRKKGNF CPICQKCYDD 

      1450       1460       1470       1480       1490       1500 
NDFDLKMMEC GDCNQWVHSK CEGLSDEQYN LLSTLPESIE FICKKCARRC DVSRNKADEW 

      1510       1520       1530       1540       1550       1560 
RQAVMEEFKS SLYSVLKLLS KSRQACALLK LSPRKKLRCS CSAGGAAGKA HSQGKLQPKA 

      1570       1580       1590       1600       1610       1620 
LQFTYNGLGS DGESQNSDDI YEFKEQHSTN RKPSTPVPCS CLQPLSQSPS FSLVDIKQKI 

      1630       1640       1650       1660       1670       1680 
ASNAYVSLAE FNYDMSQVIQ QSNCDELDIA YKELLSEQFP WFQNETKACT DALEEDMFES 

      1690       1700       1710       1720       1730       1740 
CGYEELEESP TTYAEHHTAS QAPRTGLLDI PLDDVDDLGG CAVKTRLDTR VCLFCRKSGE 

      1750       1760       1770       1780       1790       1800 
GLSGEEARLL YCGHDCWVHI NCAMWSAEVF EEIDGSLQNV HSAVARGRMI KCTVCGNRGA 

      1810       1820       1830       1840       1850       1860 
TVGCNVKSCG EHYHYPCARS IDCAFLTDKS MYCPAHARNA LKANGSPSVT YESNFEVSRP 

      1870       1880       1890       1900       1910       1920 
VYVELDRKRK KLIEPAKVQF HIGSLEVRQL GSIVPRFSDS FEAIVPINFL CSRLYWSSKE 

      1930       1940       1950       1960       1970       1980 
PWKIVEYTVR TTIQNSYSSS LTLDAGRNFT VDHTNPNCSL VQLGLAQIAR WHSSLARSDL 

      1990       2000       2010       2020       2030       2040 
LDTDWAEFPN SYVPADENTE EEPQQNADLL PPEIKDAIFE DLPHELLDGI SMLDIFMYED 

      2050       2060       2070       2080       2090       2100 
LGDKTELFAM SEQSKDGTTA TSQTGGGSVS ICDEDTRNSN SLSKQLELSN CWPASNPVED 

      2110       2120       2130       2140       2150       2160 
AMLCAARSSS QAKQRGEVLK KTATAPTRSW PKLDGGSVAA FKRRKLSKNI AEGVLLSLNQ 

      2170       2180       2190       2200       2210       2220 
RSKKEMATVA GITRRQSVCG SSELPPEGSA TMRTKSFTWS AAKCLFEKNE SREEPAKLKI 

      2230       2240       2250       2260       2270       2280 
MQMDGVDDSI TEYRIIGSDG NLSTAQFTGQ VKCERCQCTY RNYDSFQRHL GSCEPMSTSE 

      2290       2300       2310       2320       2330       2340 
SESETATGTA QLSAESLNEL QKQALAAATL SNTGGLNYLQ TSFPQVQNLA TLGQFGVQGL 

      2350       2360       2370       2380       2390       2400 
QGLQTLQLQP QSLGNGFFLS QPNAAQATSN GNDELQLYAN SLQNLAANLG GGFTLTQPTM 

      2410       2420       2430       2440       2450       2460 
STQAQPQLIA LSTNPDGTQQ FIQLPQSNGA TTQLLQTAAP AAMPTATYQT LQATNSDKKI 

      2470       2480       2490       2500       2510       2520 
VLPLRNAGKP LKTVATKAAQ QATAAAKQKQ LKSAHGVKPI QAKLQPQQQQ QQHQQHQQQQ 

      2530       2540       2550       2560       2570       2580 
HQQQQQQQQQ QQQQQTPITV AQHGGTTQLL GQNLLQPQLL FQSNAQPQTQ QLLLPQTQAQ 

      2590       2600       2610       2620       2630       2640 
NIISFVTGDG SQNQPLQYIS IPTTNDFKPQ QTTSTPTFLT APGGGATFLQ TDASGNLMLT 

      2650       2660       2670       2680       2690       2700 
TAPANSGLQM LTGQLQTQPQ VIGTLIQPQT LQLTTGADGT QSATAQQPLI LGGATGGGTT 

      2710       2720       2730       2740       2750       2760 
GLEFATATPQ VILATQPMYY GLETIVQNTV MSSQQFVSTA MPGVLSQNSS FSATTTQVFQ 

      2770       2780       2790       2800       2810       2820 
ASKIEPIVDL PAGYVVLNNA VDASGNTSWL QQSQTQATDD ATAQLLQNAG FQFQTTPTTS 

      2830       2840       2850       2860       2870       2880 
TQQTMSTDYA PPLVVTAKVP PVAQMKRNTN ANKSPISVLS KVQPQPQQSQ VVNKVLPTNL 

      2890       2900       2910       2920       2930       2940 
TSQFQRQQQA NELKNKQAAG QQTGSTCGAP PSIASKPLQK KTNLIRPIHK VEVKPKIMKQ 

      2950       2960       2970       2980       2990       3000 
APKLATSAAS MQHHQQQQSP AAINQVAKVA LLQQRLPPAP QPQQQQPQQQ QQQLHQQQQQ 

      3010       3020       3030       3040       3050       3060 
QQQQQQHMQQ HQQQQQQLSM PQLLPAQQPI ISIVNTAEPQ AATQFVITPA LQAQAQPIQL 

      3070       3080       3090       3100       3110       3120 
QEQQSQQQQQ QPAEQLINGN ATRLQHYASN SLPTNVVNPL QQQPLAASAN NSSNSNVTQQ 

      3130       3140       3150       3160       3170       3180 
NSTITINSRP TNRVLPMQQR QEPTPLSNDV VVQSPTPPKP IEEPVPAGAS TQKPIVKCYA 

      3190       3200       3210       3220       3230       3240 
QLEQKSPGYE TELKTNITLD NLEQTNSITT LQLQQPQQGP IYGEQIFEKQ SEAQVQLEKP 

      3250       3260       3270       3280       3290       3300 
KHNDLMLLEA TSCQQQQQQQ QQHMEMVVDN GFQLTSNESC LLEKHGFNVE AVPMDTEDHY 

      3310       3320       3330       3340       3350       3360 
ASMKNGSGGG AAEGIGQVDD AEEDEDDDDD FSLKMATSAC NDHEMSDSEE PAVKEKISKI 

      3370       3380       3390       3400       3410       3420 
LDNLTNDDCA DSITTATTVE ASAGYQQMVE DVLATTAAGS VSTDDETFTA TAEAVEAAAS 

      3430       3440       3450       3460       3470       3480 
YINEMAEAHE LQLKQLQAGV ELDLKKPKLD VPQQQPNTVP TNVVPTAAAP QQPPPMRDPK 

      3490       3500       3510       3520       3530       3540 
KISGPHLLYE IQSEDGFTYK SSSIAEIWEK VFEAVQVARR AHGLTPLPEG PLADMSGVQM 

      3550       3560       3570       3580       3590       3600 
IGLKTNALKY LIEQLPGVEK CVKYTPKYHK RNGNVSTAAG GGHAASTAGS NAAALGAGAD 

      3610       3620       3630       3640       3650       3660 
AQALIDYGSD QEELQENAYE CARCEPYVSR SEYDMFSWLA SRHRKQPIQV FVQPSDNELV 

      3670       3680       3690       3700       3710       3720 
PRRGTGSNLP MAMKYRTLKE TYKDYVGVFR SHIHGRGLYC TKDIEAGEMV IEYAGELIRS 

      3730       3740       3750       3760       3770       3780 
TLTDKRERYY DSRGIGCYMF KIDDNLVVDA TMRGNAARFI NHSCEPNCYS KVVDILGHKH 

      3790       3800       3810       3820 
IIIFALRRIV QGEELTYDYK FPFEDEKIPC SCGSKRCRKY LN 

« Hide

References

[1]"Evolution of genes and genomes on the Drosophila phylogeny."
Drosophila 12 genomes consortium
Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Tucson 15010-1051.87.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH940650 Genomic DNA. Translation: EDW68309.1.
RefSeqXP_002054789.1. XM_002054753.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7244.FBpp0237016.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0238524; FBpp0237016; FBgn0014844.
GeneID6630169.
KEGGdvi:Dvir_GJ22599.

Organism-specific databases

FlyBaseFBgn0014844. Dvir\trx.

Phylogenomic databases

KOK09186.
OMATVGCNVK.

Family and domain databases

Gene3D3.30.40.10. 1 hit.
InterProIPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR016569. MeTrfase_trithorax.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR011011. Znf_FYVE_PHD.
IPR001628. Znf_hrmn_rcpt.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PIRSFPIRSF010354. Methyltransferase_trithorax. 1 hit.
SMARTSM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00184. RING. 4 hits.
SM00317. SET. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMSSF57903. SSF57903. 2 hits.
PROSITEPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4M059_DROVI
AccessionPrimary (citable) accession number: B4M059
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)