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Protein

Hexokinase

Gene

Dvir\GJ23870

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Hexokinase (EC:2.7.1.1)
Gene namesi
Name:Dvir\GJ23870Imported
ORF Names:Dvir_GJ23870Imported, GJ23870Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0210965. Dvir\GJ23870.

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0238287.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB4LYE5.
KOiK00844.
OMAiRFICETI.
OrthoDBiEOG7S21X5.
PhylomeDBiB4LYE5.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4LYE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDPKQKYPE AYEICEKFML NKQHMDEIVN RLTKEINMGL TRDTHPRATV
60 70 80 90 100
KCFVTYVQEL PTGNERGKYL ALDLGGTNFR VLLVNLINDR DIDITGKTYA
110 120 130 140 150
ISKELQEGSG IKLFDFIARC LAEFCKEHKM EQSNTPLGFT FSFPCKQVGI
160 170 180 190 200
DNGTLVAWTK GFKAEGVVNQ NVVELLRDAI KRRGDFKVNV VAILNDTTGT
210 220 230 240 250
LMSCAFNHRN CKIGMIVGTG SNACYVEKTA NTQTFDGYLS STKPNMIINC
260 270 280 290 300
EWGAFGDNGV LDFIRTSYDH EVDKQSINPK KQIFEKCISG MYMGELVRLV
310 320 330 340 350
LLELMEKEAI FKGQTSQSIL IKGKFDTSFI TEIESDQPGS HRNAALVMDR
360 370 380 390 400
LGIRTNNEKD LGCLRFICET ISTRSARLAA CGLVCLINKM NVKDLTVGID
410 420 430 440 450
GSVYRYHPNY HRLLTENMNM LLKGSVKFEL VLSEDGSGRG AALIAAVCAK
Length:450
Mass (Da):50,300
Last modified:September 23, 2008 - v1
Checksum:iB2726BA08F1A9EEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940650 Genomic DNA. Translation: EDW66941.1.
RefSeqiXP_002053421.1. XM_002053385.1.

Genome annotation databases

EnsemblMetazoaiFBtr0239795; FBpp0238287; FBgn0210965.
GeneIDi6630262.
KEGGidvi:Dvir_GJ23870.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940650 Genomic DNA. Translation: EDW66941.1.
RefSeqiXP_002053421.1. XM_002053385.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7244.FBpp0238287.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0239795; FBpp0238287; FBgn0210965.
GeneIDi6630262.
KEGGidvi:Dvir_GJ23870.

Organism-specific databases

FlyBaseiFBgn0210965. Dvir\GJ23870.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB4LYE5.
KOiK00844.
OMAiRFICETI.
OrthoDBiEOG7S21X5.
PhylomeDBiB4LYE5.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15010-1051.87Imported.

Entry informationi

Entry nameiB4LYE5_DROVI
AccessioniPrimary (citable) accession number: B4LYE5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 27, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.