Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Dvir\GJ20981

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei121 – 1211SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:Dvir\GJ20981Imported
ORF Names:Dvir_GJ20981Imported, GJ20981Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0208116. Dvir\GJ20981.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0235398.

Structurei

3D structure databases

ProteinModelPortaliB4LPC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni270 – 2712Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0240.
InParanoidiB4LPC4.
KOiK00006.
OMAiTHINVKY.
OrthoDBiEOG7ZKSBS.
PhylomeDBiB4LPC4.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.

Sequencei

Sequence statusi: Complete.

B4LPC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDRLNVCII GSGNWATTIA RNVGLNVANS QLMEPKVNMY VYEEYIDGRK
60 70 80 90 100
LTEIINTTHI NVKYMPNFVL PPNVFALDDV VTTARDADIL IFAIPPTFVS
110 120 130 140 150
SCCKTLLGKV KPLAHAVSLI KGFERGDDGQ ILLISHLIMR QLKIPCSVLV
160 170 180 190 200
GCNLAHEISN GNFAEGTIGC RDQKYMRILQ DIFKSATFRV VVTDDADCVE
210 220 230 240 250
ICNSLRNVIA FGAGCADGME LNENTKAGII RRGFLEILQF VDVFYPGSRL
260 270 280 290 300
ATFFESCGLS DLVTSCYANR NRKLAEAFVK TGQPLSELEH ILVPGHEPLG
310 320 330 340 350
PITSELIHIM LKKKGLEDKF PLFTTIYRIC TGVYPLSRLV ETLRFAREDI

YHPNHIFQL
Length:359
Mass (Da):40,051
Last modified:September 23, 2008 - v1
Checksum:i2F6AA781FDC1D20E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940648 Genomic DNA. Translation: EDW60233.1.
RefSeqiXP_002049040.1. XM_002049004.1.

Genome annotation databases

EnsemblMetazoaiFBtr0236906; FBpp0235398; FBgn0208116.
GeneIDi6624941.
KEGGidvi:Dvir_GJ20981.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940648 Genomic DNA. Translation: EDW60233.1.
RefSeqiXP_002049040.1. XM_002049004.1.

3D structure databases

ProteinModelPortaliB4LPC4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7244.FBpp0235398.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0236906; FBpp0235398; FBgn0208116.
GeneIDi6624941.
KEGGidvi:Dvir_GJ20981.

Organism-specific databases

FlyBaseiFBgn0208116. Dvir\GJ20981.

Phylogenomic databases

eggNOGiCOG0240.
InParanoidiB4LPC4.
KOiK00006.
OMAiTHINVKY.
OrthoDBiEOG7ZKSBS.
PhylomeDBiB4LPC4.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15010-1051.87Imported.

Entry informationi

Entry nameiB4LPC4_DROVI
AccessioniPrimary (citable) accession number: B4LPC4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 29, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.