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B4LNY6

- B4LNY6_DROVI

UniProt

B4LNY6 - B4LNY6_DROVI

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Protein
DNA ligase
Gene
Dvir\GJ20456, Dvir_GJ20456, GJ20456
Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dvir\GJ20456Imported
ORF Names:Dvir_GJ20456Imported, GJ20456Imported
OrganismiDrosophila virilis (Fruit fly)
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000008792: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0207596. Dvir\GJ20456.

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0234873.

Structurei

3D structure databases

ProteinModelPortaliB4LNY6.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
InParanoidiB4LNY6.
KOiK10747.
OMAiMVKMLEG.
OrthoDBiEOG7RFTGN.
PhylomeDBiB4LNY6.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4LNY6-1 [UniParc]FASTAAdd to Basket

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MPPSKITKME LNPEVTEGEG IEIYDPSLES YHPLKHAYWK AERVTPYLAL    50
ARTFQVIEET SGRLKMIDIL SNFFCSVMLV SPEDLVPCVY LSINQLAPAY 100
EGLELGVAET TLMKAICKAT GRNLAHIKSQ THLTGDLGIV AEQSRVSQRM 150
MFRPKPLNVR GVFTKLKEIA KISGQAKMTL VYDVFVACRL SEARFFIRSL 200
IGKLRIGIAE QSLLTALAIA LVKRNHINDC KTNKVCDVYK DEIAETTLIL 250
KTTFCQCPNY DIIIPAILKY DIKELQERCP MHPGMPLRPM LAQPTKGVLE 300
VLERFSGMHI TCEWKYDGER AQIHLNELGE ISIFSRNSEN NTPKYPDLIA 350
RSKSFLKTDV QSYIIDSEIV AWDIERKQIL PFQILSTRKR KNVDIEDIKV 400
QVCVYIFDLL FINGVSLVTK PLSLRRKMLF EHFQEVEGQW KFATALDTND 450
MDEVQQFLEE SIKGNCEGLM VKTLEEEATY EIAKRSRNWL KLKKDYLSNV 500
GDSLDLVVIG GYKGKGRRTG TYGGFLLACY DTENEEYQSI CKIGTGFTDD 550
DLRLHSEFFN KHVTGSAKSY FRYDPSLEPD VWFEPVQVWE VKCADLSLSP 600
IHRASIGIVD AERGISLRFP RFIRIRDDKS PENATDANQV AHMYKSQDQV 650
RNNQKSSSLM DIESDFY 667
Length:667
Mass (Da):76,143
Last modified:September 23, 2008 - v1
Checksum:i3259275AC55321E2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH940648 Genomic DNA. Translation: EDW61155.1.
RefSeqiXP_002049962.1. XM_002049926.1.

Genome annotation databases

EnsemblMetazoaiFBtr0236381; FBpp0234873; FBgn0207596.
GeneIDi6624981.
KEGGidvi:Dvir_GJ20456.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH940648 Genomic DNA. Translation: EDW61155.1 .
RefSeqi XP_002049962.1. XM_002049926.1.

3D structure databases

ProteinModelPortali B4LNY6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7244.FBpp0234873.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0236381 ; FBpp0234873 ; FBgn0207596 .
GeneIDi 6624981.
KEGGi dvi:Dvir_GJ20456.

Organism-specific databases

FlyBasei FBgn0207596. Dvir\GJ20456.

Phylogenomic databases

eggNOGi COG1793.
InParanoidi B4LNY6.
KOi K10747.
OMAi MVKMLEG.
OrthoDBi EOG7RFTGN.
PhylomeDBi B4LNY6.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15010-1051.87.

Entry informationi

Entry nameiB4LNY6_DROVI
AccessioniPrimary (citable) accession number: B4LNY6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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