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Protein

Aldose 1-epimerase

Gene

Dvir\GJ11231

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:Dvir\GJ11231Imported
ORF Names:Dvir_GJ11231Imported, GJ11231Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0198492. Dvir\GJ11231.

Interactioni

Protein-protein interaction databases

STRINGi7244.FBpp0225648.

Structurei

3D structure databases

ProteinModelPortaliB4LD99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2017.
InParanoidiB4LD99.
KOiK01785.
OMAiYINETRY.
OrthoDBiEOG7V7666.
PhylomeDBiB4LD99.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

B4LD99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVKIEEEIF GLAKNPFTKI PEMVRRFTMT NTNQMSVSVI QLGAIIQSVR
60 70 80 90 100
MPDAYQKIED VCLGFDDIAS YVNTKAAYIG GTLGRVANRV ANGEYTVGET
110 120 130 140 150
KYELTKNFKN TYQLHGGFVG FDSVIWEVVR KSDLGITFRH VSPDGHEGYP
160 170 180 190 200
GNLTTTITYW LDNQNRLGVR YEAFTDKMTP VNLSNHAYFN LAGHATGAKG
210 220 230 240 250
LAEHTVEIAS TRIIDTDDDQ IPTGKFLDVD DTVFDMRLPV LLGDRLKQFD
260 270 280 290 300
NRLIKGYDNC FVVNEGNDTG INLVAKLVHP PSGRAMEIYS NQPGLQFYTA
310 320 330 340 350
NNLPDEENGD APMIGKECTH YRKHGSFCVE TEKFPDAMNQ HHPEFPSVFL
360 370
HPGEKYLHEV IYKFNVEESW KCCCNNK
Length:377
Mass (Da):42,491
Last modified:September 23, 2008 - v1
Checksum:iEFEFC8C3477CCDB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940647 Genomic DNA. Translation: EDW71006.1.
RefSeqiXP_002048664.1. XM_002048628.1.

Genome annotation databases

EnsemblMetazoaiFBtr0227156; FBpp0225648; FBgn0198492.
GeneIDi6624095.
KEGGidvi:Dvir_GJ11231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940647 Genomic DNA. Translation: EDW71006.1.
RefSeqiXP_002048664.1. XM_002048628.1.

3D structure databases

ProteinModelPortaliB4LD99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7244.FBpp0225648.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0227156; FBpp0225648; FBgn0198492.
GeneIDi6624095.
KEGGidvi:Dvir_GJ11231.

Organism-specific databases

FlyBaseiFBgn0198492. Dvir\GJ11231.

Phylogenomic databases

eggNOGiCOG2017.
InParanoidiB4LD99.
KOiK01785.
OMAiYINETRY.
OrthoDBiEOG7V7666.
PhylomeDBiB4LD99.

Enzyme and pathway databases

UniPathwayiUPA00242.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15010-1051.87Imported.

Entry informationi

Entry nameiB4LD99_DROVI
AccessioniPrimary (citable) accession number: B4LD99
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 4, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.