Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

Pgam5

Organism
Drosophila mojavensis (Fruit fly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrialBy similarity (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homologBy similarity
Gene namesi
Name:Pgam5By similarity
ORF Names:GI16420
OrganismiDrosophila mojavensis (Fruit fly)
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000009192 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0139168 Dmoj\GI16420

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003907061 – 289Serine/threonine-protein phosphatase Pgam5, mitochondrialAdd BLAST289

Proteomic databases

PRIDEiB4L6S9

Expressioni

Gene expression databases

BgeeiFBgn0139168

Interactioni

Subunit structurei

Interacts with Pk92B/ASK1.By similarity

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4L6S9
SMRiB4L6S9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiB4L6S9
KOiK15637
OMAiHLTNRIP
OrthoDBiEOG091G0DEJ
PhylomeDBiB4L6S9

Family and domain databases

CDDicd07067 HP_PGM_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR013078 His_Pase_superF_clade-1
IPR029033 His_PPase_superfam
PfamiView protein in Pfam
PF00300 His_Phos_1, 2 hits
SMARTiView protein in SMART
SM00855 PGAM, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit

Sequencei

Sequence statusi: Complete.

B4L6S9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKFAAFACG TGAGFAAYYF QKLRDPLQVV HNSWTNSERH ISECALWDSN
60 70 80 90 100
WDYRDPKSLA RPMKNDKPQE QNRYNADLEK NVSKYARHII LIRHGEYLDV
110 120 130 140 150
GETDETHHLT DRGRLQAKYT GKRLHELGIK WDKVIASNMV RAQETAEIIL
160 170 180 190 200
NEIDFDKTKV KSCSYLREGA PIPPQPPVGH WKPEASQFFR DGARIEAAFR
210 220 230 240 250
RYFHRALPDQ EKDSYTLIVG HGNVIRYFVC RALQFPAEGW LRININHASI
260 270 280
TWLTISPSGN VSIKYLGDTG FIPAKHLTNR IPREAKNVV
Length:289
Mass (Da):33,293
Last modified:September 23, 2008 - v1
Checksum:i8258DE2CBA9AA030
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933812 Genomic DNA Translation: EDW06075.1
RefSeqiXP_002011233.1, XM_002011197.2

Genome annotation databases

EnsemblMetazoaiFBtr0167145; FBpp0165637; FBgn0139168
GeneIDi6585605
KEGGidmo:Dmoj_GI16420

Similar proteinsi

Entry informationi

Entry nameiPGAM5_DROMO
AccessioniPrimary (citable) accession number: B4L6S9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 19, 2010
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health