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Protein

Aldose 1-epimerase

Gene

Dmoj\GI11556

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:Dmoj\GI11556Imported
ORF Names:Dmoj_GI11556Imported, GI11556Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000009192 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0134316. Dmoj\GI11556.

Structurei

3D structure databases

ProteinModelPortaliB4KV41.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

InParanoidiB4KV41.
KOiK01785.
OMAiGQLYDHQ.
OrthoDBiEOG7V7666.
PhylomeDBiB4KV41.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

B4KV41-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRVVEDVFG IAVNPMTQKT DHVRRFTLCS EKGMSVAILT LGGIIQSIRV
60 70 80 90 100
PDANAKLEDV CLGYDDVAGY YRNQKFYIGA IIGRVADRVA RGRFSLCSKD
110 120 130 140 150
ISLSRNHKDH YHLNGGYVGF DSVIWDVVGI HKDGVTFQHV SPDGHEGYPG
160 170 180 190 200
EVTVNINYSL NEAGCLGLRI EARAKETTCI NIGHHCLFNL AGHSSGRDTL
210 220 230 240 250
YQHMIMIKAN KIVDTDLEQI PTGKLMPTRN TPYDFSTLTN LGKRLNQVNR
260 270 280 290 300
CPISGFDNNY CVDVDPNQVK LVARAVHPCS GRFVEIHTNQ PGVHFSTANG
310 320 330 340 350
LPQEDRGDVP HVGKGGAHYS QHSAFCLQTQ KYPDAMNNPE FPTVIINPGQ
360
LYDHQVVYRF GACPKRV
Length:367
Mass (Da):40,695
Last modified:September 22, 2008 - v1
Checksum:i840DEC55BC6745D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933809 Genomic DNA. Translation: EDW19381.1.
RefSeqiXP_002008905.1. XM_002008869.1.

Genome annotation databases

EnsemblMetazoaiFBtr0162281; FBpp0160773; FBgn0134316.
GeneIDi6583232.
KEGGidmo:Dmoj_GI11556.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933809 Genomic DNA. Translation: EDW19381.1.
RefSeqiXP_002008905.1. XM_002008869.1.

3D structure databases

ProteinModelPortaliB4KV41.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0162281; FBpp0160773; FBgn0134316.
GeneIDi6583232.
KEGGidmo:Dmoj_GI11556.

Organism-specific databases

FlyBaseiFBgn0134316. Dmoj\GI11556.

Phylogenomic databases

InParanoidiB4KV41.
KOiK01785.
OMAiGQLYDHQ.
OrthoDBiEOG7V7666.
PhylomeDBiB4KV41.

Enzyme and pathway databases

UniPathwayiUPA00242.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15081-1352.22Imported.

Entry informationi

Entry nameiB4KV41_DROMO
AccessioniPrimary (citable) accession number: B4KV41
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: February 3, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.