Dmoj\GI11556

Functionⁱ

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityⁱ

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayⁱ: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Binding siteⁱ	257	SubstrateUniRule annotation		1

GO - Molecular functionⁱ

aldose 1-epimerase activity Source: UniProtKB-EC
carbohydrate binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

hexose metabolic process Source: UniProtKB-UniPathway

Complete GO annotation...

Keywordsⁱ

Molecular function	IsomeraseUniRule annotationImported
Biological process	Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayⁱ	UPA00242.

UniPathwayⁱ

UPA00242.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation) Alternative name(s): Galactose mutarotaseUniRule annotation
Gene namesⁱ	Name:Dmoj\GI11556Imported ORF Names:Dmoj_GI11556Imported, GI11556Imported
Organismⁱ	Drosophila mojavensis (Fruit fly)Imported
Taxonomic identifierⁱ	7230 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophila › Drosophila › repleta group › mulleri subgroup › mojavensis species complex
Proteomesⁱ	UP000009192 Componentⁱ: Unassembled WGS sequence

Organism-specific databases

Drosophila genome database More...FlyBaseⁱ	FBgn0134316. Dmoj\GI11556.

FlyBaseⁱ

FBgn0134316. Dmoj\GI11556.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	B4KV41.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

InParanoidⁱ	B4KV41.
KEGG Orthology (KO) More...KOⁱ	K01785.
OMAⁱ	RNTPYDF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0COE.
PhylomeDBⁱ	B4KV41.

Family and domain databases

Gene3Dⁱ	2.70.98.10. 1 hit.
InterProⁱ	View protein in InterPro IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. GH-type_carb-bd.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01263. Aldose_epim. 1 hit.
PIRSFⁱ	PIRSF005096. GALM. 1 hit.
SUPFAMⁱ	SSF74650. SSF74650. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

B4KV41-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVRVVEDVFG IAVNPMTQKT DHVRRFTLCS EKGMSVAILT LGGIIQSIRV 
        60         70         80         90        100
PDANAKLEDV CLGYDDVAGY YRNQKFYIGA IIGRVADRVA RGRFSLCSKD 
       110        120        130        140        150
ISLSRNHKDH YHLNGGYVGF DSVIWDVVGI HKDGVTFQHV SPDGHEGYPG 
       160        170        180        190        200
EVTVNINYSL NEAGCLGLRI EARAKETTCI NIGHHCLFNL AGHSSGRDTL 
       210        220        230        240        250
YQHMIMIKAN KIVDTDLEQI PTGKLMPTRN TPYDFSTLTN LGKRLNQVNR 
       260        270        280        290        300
CPISGFDNNY CVDVDPNQVK LVARAVHPCS GRFVEIHTNQ PGVHFSTANG 
       310        320        330        340        350
LPQEDRGDVP HVGKGGAHYS QHSAFCLQTQ KYPDAMNNPE FPTVIINPGQ 
       360 
LYDHQVVYRF GACPKRV

Length:367

Mass (Da):40,695

Last modified:September 23, 2008 - v1

Checksum:ⁱ840DEC55BC6745D9

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CH933809 Genomic DNA. Translation: EDW19381.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002008905.1. XM_002008869.2.

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0162281; FBpp0160773; FBgn0134316.
GeneIDⁱ	6583232.
KEGGⁱ	dmo:Dmoj_GI11556.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CH933809 Genomic DNA. Translation: EDW19381.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002008905.1. XM_002008869.2.

3D structure databases

ProteinModelPortalⁱ	B4KV41.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0162281; FBpp0160773; FBgn0134316.
GeneIDⁱ	6583232.
KEGGⁱ	dmo:Dmoj_GI11556.

Organism-specific databases

Drosophila genome database More...FlyBaseⁱ	FBgn0134316. Dmoj\GI11556.

FlyBaseⁱ

FBgn0134316. Dmoj\GI11556.

Phylogenomic databases

InParanoidⁱ	B4KV41.
KEGG Orthology (KO) More...KOⁱ	K01785.
OMAⁱ	RNTPYDF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0COE.
PhylomeDBⁱ	B4KV41.

Enzyme and pathway databases

UniPathwayⁱ	UPA00242.

UniPathwayⁱ

UPA00242.

Family and domain databases

Gene3Dⁱ	2.70.98.10. 1 hit.
InterProⁱ	View protein in InterPro IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. GH-type_carb-bd.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01263. Aldose_epim. 1 hit.
PIRSFⁱ	PIRSF005096. GALM. 1 hit.
SUPFAMⁱ	SSF74650. SSF74650. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B4KV41_DROMO
Accessionⁱ	B4KV41Primary (citable) accession number: B4KV41
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 23, 2008
	Last sequence update:	September 23, 2008
	Last modified:	June 7, 2017
	This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - B4KV41 (B4KV41_DROMO)

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Aldose 1-epimerase

Select a section on the left to see content.

Functionⁱ

Catalytic activityⁱ

Pathwayⁱ: hexose metabolism

Sites

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Organism-specific databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B4KV41 (B4KV41_DROMO)

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Aldose 1-epimerase

Dmoj\GI11556

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: hexose metabolism

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

Pathwayⁱ: hexose metabolism

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ