Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

6-phosphofructokinase

Gene

Dmoj\GI20539

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphofructokinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. fructose 6-phosphate metabolic process Source: InterPro
  2. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00182.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphofructokinaseUniRule annotation (EC:2.7.1.11UniRule annotation)
Alternative name(s):
PhosphohexokinaseUniRule annotation
Gene namesi
Name:Dmoj\GI20539Imported
ORF Names:Dmoj_GI20539Imported, GI20539Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000009192: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0143275. Dmoj\GI20539.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliB4KSJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.UniRule annotation

Phylogenomic databases

InParanoidiB4KSJ9.
KOiK00850.
OMAiVYHMASK.
OrthoDBiEOG7ZSHV5.
PhylomeDBiB4KSJ9.

Family and domain databases

HAMAPiMF_00339. Phosphofructokinase.
InterProiIPR009161. 6-phosphofructokinase_euk.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 3 hits.
[Graphical view]
PIRSFiPIRSF000533. ATP_PFK_euk. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 3 hits.
TIGRFAMsiTIGR02478. 6PF1K_euk. 1 hit.
PROSITEiPS00433. PHOSPHOFRUCTOKINASE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4KSJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSDTNQRFL ARGSQRDKGL AVFTSGGDSQ GMNAAVRACV RMAIYLGCKV
60 70 80 90 100
YFIREGYQGM VDGGDCIQEA SWSSVSSIIH RGGTIIGSAR CKDFRERAGR
110 120 130 140 150
LKAANNLVQR GITNLVVIGG DGSLTGANLF RQEWSSLLDE LEKNKSITPE
160 170 180 190 200
QKNKYNVLHI VGLVGSIDND FCGTDMTIGT DTALHRIIEA IDAIASTAYS
210 220 230 240 250
HQRTFIMEVM GRHCGYLPVV AGVISEADYV FLPEYPPPQD WPDRLTLKLD
260 270 280 290 300
QASNQPSAIS SRFYLAISAA IATEADFMFI PEEPAPTNWQ DDLCKKLAQE
310 320 330 340 350
RSAGQRLNIV IVAEGASDRE GNPITAEQVR KVIDERLKHD ARITVLGHVQ
360 370 380 390 400
RGGNPSAFDR VLACRMGAEA TLALMEATPE SVPVVISLDG NQTVRVPLME
410 420 430 440 450
CVERTQAVAK AMAERRWADA VKLRGRSFER NLETYKMLTR LKPPKENFDE
460 470 480 490 500
QGKGIEGYRL AVMHIGAPAC GMNAAVRSFV RNAIYRGDVV YGINDGVEGL
510 520 530 540 550
IAGNVRELGW SDVSGWVGQG GAYLGTKRTL PEGKFKEIAA RLKEFKIQGL
560 570 580 590 600
LIIGGFESYH AAGQISDQRD NYPEFCIPIV VVPATISNNV PGTEFSLGCD
610 620 630 640 650
TGLNEITEIC DRIRQSAQGT KRRVFVIETM GGYSGYLATL AGLAGGADAA
660 670 680 690 700
YIYEEKFSIK DLQQDVYHMA SKMAEGVSRG LILRNEKASE NYTTDFIYRL
710 720 730 740 750
YSEEGKGLFT CRMNILGHMQ QGGSPSPFDR NMGTKMAAKC VDWLATQIKN
760 770 780 790 800
NIDSNGVVNC KSTDTATLLG IVSRQYRFTP LVDLIADTNF DQRIPKKQWW
810 820 830
LRLRPLLRIL AKHDSAYEEE GMYITVEEEC ATDAVA
Length:836
Mass (Da):92,036
Last modified:September 23, 2008 - v1
Checksum:i38B8C268683673ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933808 Genomic DNA. Translation: EDW09504.1.
RefSeqiXP_002005569.1. XM_002005533.1.

Genome annotation databases

EnsemblMetazoaiFBtr0171264; FBpp0169756; FBgn0143275.
GeneIDi6579687.
KEGGidmo:Dmoj_GI20539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933808 Genomic DNA. Translation: EDW09504.1.
RefSeqiXP_002005569.1. XM_002005533.1.

3D structure databases

ProteinModelPortaliB4KSJ9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0171264; FBpp0169756; FBgn0143275.
GeneIDi6579687.
KEGGidmo:Dmoj_GI20539.

Organism-specific databases

FlyBaseiFBgn0143275. Dmoj\GI20539.

Phylogenomic databases

InParanoidiB4KSJ9.
KOiK00850.
OMAiVYHMASK.
OrthoDBiEOG7ZSHV5.
PhylomeDBiB4KSJ9.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00182.

Family and domain databases

HAMAPiMF_00339. Phosphofructokinase.
InterProiIPR009161. 6-phosphofructokinase_euk.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 3 hits.
[Graphical view]
PIRSFiPIRSF000533. ATP_PFK_euk. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 3 hits.
TIGRFAMsiTIGR02478. 6PF1K_euk. 1 hit.
PROSITEiPS00433. PHOSPHOFRUCTOKINASE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15081-1352.22Imported.

Entry informationi

Entry nameiB4KSJ9_DROMO
AccessioniPrimary (citable) accession number: B4KSJ9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.