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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Dmoj\GI21131

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei121 – 1211SubstrateUniRule annotation

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:Dmoj\GI21131Imported
ORF Names:Dmoj_GI21131Imported, GI21131Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000009192 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0143863. Dmoj\GI21131.

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliB4KS69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni270 – 2712Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

InParanoidiB4KS69.
KOiK00006.
OMAiTHINVKY.
OrthoDBiEOG7ZKSBS.
PhylomeDBiB4KS69.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.

Sequencei

Sequence statusi: Complete.

B4KS69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADRLNVCII GSGNWATTIA RNVGNNVANS QLMEPKVNMY VYEEIIEGRK
60 70 80 90 100
LTEIINSTHI NVKYMPDFVL PMNIVAYDDV VTTARDADIL IFAIPPTFVN
110 120 130 140 150
SCCKTLLGKV KPLAHAVSLI KGFERGDDGQ ILLISHLIMR QLKIPCSVLV
160 170 180 190 200
GCNLAHEVSN NNFAEGTIGC RDQKYMRILQ DLFKSNTFRV VVTDDADCVE
210 220 230 240 250
ICSTLRNIIA FGAGLADGME LNENTKAGVI RRGFLETLQF VDVFYPGSRL
260 270 280 290 300
ATFFESCGLS DLVTSCYANR NRKLAEAFVK TGQPLNELES LLVPGHEPLG
310 320 330 340 350
PVTAELVHIM LKKKGLEEKF PLFTAVFRIC TGVYPLSRLV ETLRYAREDI

YHPNHIFPL
Length:359
Mass (Da):39,992
Last modified:September 23, 2008 - v1
Checksum:i75D350F3F7050921
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933808 Genomic DNA. Translation: EDW10505.1.
RefSeqiXP_002006570.1. XM_002006534.1.

Genome annotation databases

EnsemblMetazoaiFBtr0171856; FBpp0170348; FBgn0143863.
GeneIDi6580767.
KEGGidmo:Dmoj_GI21131.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933808 Genomic DNA. Translation: EDW10505.1.
RefSeqiXP_002006570.1. XM_002006534.1.

3D structure databases

ProteinModelPortaliB4KS69.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0171856; FBpp0170348; FBgn0143863.
GeneIDi6580767.
KEGGidmo:Dmoj_GI21131.

Organism-specific databases

FlyBaseiFBgn0143863. Dmoj\GI21131.

Phylogenomic databases

InParanoidiB4KS69.
KOiK00006.
OMAiTHINVKY.
OrthoDBiEOG7ZKSBS.
PhylomeDBiB4KS69.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15081-1352.22Imported.

Entry informationi

Entry nameiB4KS69_DROMO
AccessioniPrimary (citable) accession number: B4KS69
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 29, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.