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Protein

Angiotensin-converting enzyme

Gene

Dmoj\GI10464

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dmoj\GI10464Imported
ORF Names:Dmoj_GI10464Imported, GI10464Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000009192 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0133228. Dmoj\GI10464.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500281414924 – 630Angiotensin-converting enzymeSequence analysisAdd BLAST607

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0133228.

Structurei

3D structure databases

ProteinModelPortaliB4KI52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

InParanoidiB4KI52.
KOiK01283.
OMAiSAWDFYQ.
OrthoDBiEOG091G033S.
PhylomeDBiB4KI52.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

B4KI52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLLVYCLV AFALVPWLPY GTAYETCSAS AQQAHCFFEQ ENSKLRERYH
60 70 80 90 100
SEYSAAFTYN TNVTEENRQA MIAVYAEGAR QNKLLAQTIR AANYAKSEDG
110 120 130 140 150
NIRRQARMLQ ELGADVLEPS DYLELKNAIS AMQSNYATTT VCSYTNRTNC
160 170 180 190 200
SLTLEPHIQE RLSNSRDPAE LAWYWREWYD KAGTPMRDNF AKYVRLTRKA
210 220 230 240 250
ANMNGYRSYA DYWVHFYEDA TFESQLDATY KALLPFYRQI HGYVRYRLRQ
260 270 280 290 300
HYGPEVVPAE GNIPMHLLGN MWGQSWNEVI DLFTPYPERP FVDVTSEMER
310 320 330 340 350
QAYSVQKLFE LGDQFFQSLG MRALPTTFWN RSVLTRPADR EVVCHASAWD
360 370 380 390 400
FYQDSDVRIK MCTEVNTHYL YVVHHELGHI QYYLQYEQQP AVYRGAPNPG
410 420 430 440 450
FHEAVGDVIA LSVMSAKHLQ SINLTSNGTL DEESRINELF KRALSKIVFL
460 470 480 490 500
PFGYTMDKYR YAVFRGELDE SQWNCGFWQM RSEFGGVEPP MARSDKDFDP
510 520 530 540 550
PAKYHIDADV EYLRYFAAHI FQFQFHKALC RLAGQYAPGD STRTLDNCDI
560 570 580 590 600
FGSRRAGDAF KKFLSAGNSR HWKEVLEEFT GETEMDPAAL LEYFDPLYQW
610 620 630
LKRENKRLGV PLGWEETNKI PSNCCGAFST
Length:630
Mass (Da):73,062
Last modified:September 23, 2008 - v1
Checksum:i61F160A2BD3029C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933807 Genomic DNA. Translation: EDW12345.1.
RefSeqiXP_002002903.1. XM_002002867.2.

Genome annotation databases

EnsemblMetazoaiFBtr0161189; FBpp0159681; FBgn0133228.
GeneIDi6576923.
KEGGidmo:Dmoj_GI10464.

Similar proteinsi

Entry informationi

Entry nameiB4KI52_DROMO
AccessioniPrimary (citable) accession number: B4KI52
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported