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Protein

Mitogen-activated protein kinase

Gene

Dmoj\GI10639

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:Dmoj\GI10639Imported
ORF Names:Dmoj_GI10639Imported, GI10639Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000009192: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0133403. Dmoj\GI10639.

Structurei

3D structure databases

ProteinModelPortaliB4KHP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotation

Phylogenomic databases

InParanoidiB4KHP0.
KOiK04440.
OMAiDCLFPAD.
OrthoDBiEOG7PCJGV.
PhylomeDBiB4KHP0.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4KHP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAHHYTVEV GDTNFTILSR YIKLRPIGSG AQGIVCAAYD TVTEQNVAIK
60 70 80 90 100
KLSRPFQNVT HAKRAYREFK LMKLVNHKNI IGLLNAFTPQ RNLEEFQDVY
110 120 130 140 150
LVMELMDANL CQVIQMDLDH DRMSYLLYQM LCGIKHLHSA GIIHRDLKPS
160 170 180 190 200
NIVVKADCTL KILDFGLART AGTTFMMTPY VVTRYYRAPE VILGMGYTEN
210 220 230 240 250
VDIWSVGCIM GEMIRGGVLF PGTDHIDQWN KIIEQLGTPS PSFMQRLQPT
260 270 280 290 300
VRNYVENRPR YTGYAFDRLF PDGLFPNDNS QNSRRKASEA RDLLSKMLVI
310 320 330 340 350
DPEQRISVDR ALQHEYINVW YDAEEVDAPA PEPYDHSVDE REHTVEQWKE
360
LIYEEVMDYE AHNVNR
Length:366
Mass (Da):42,242
Last modified:September 23, 2008 - v1
Checksum:i4D92709358AC6F8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933807 Genomic DNA. Translation: EDW12319.1.
RefSeqiXP_002002877.1. XM_002002841.1.

Genome annotation databases

EnsemblMetazoaiFBtr0161364; FBpp0159856; FBgn0133403.
GeneIDi6576897.
KEGGidmo:Dmoj_GI10639.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933807 Genomic DNA. Translation: EDW12319.1.
RefSeqiXP_002002877.1. XM_002002841.1.

3D structure databases

ProteinModelPortaliB4KHP0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0161364; FBpp0159856; FBgn0133403.
GeneIDi6576897.
KEGGidmo:Dmoj_GI10639.

Organism-specific databases

FlyBaseiFBgn0133403. Dmoj\GI10639.

Phylogenomic databases

InParanoidiB4KHP0.
KOiK04440.
OMAiDCLFPAD.
OrthoDBiEOG7PCJGV.
PhylomeDBiB4KHP0.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15081-1352.22Imported.

Entry informationi

Entry nameiB4KHP0_DROMO
AccessioniPrimary (citable) accession number: B4KHP0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.