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Protein

Angiotensin-converting enzyme

Gene

Dmoj\GI12636

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dmoj\GI12636Imported
ORF Names:Dmoj_GI12636Imported, GI12636Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000009192 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0135393. Dmoj\GI12636.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500815787919 – 616Angiotensin-converting enzymeSequence analysisAdd BLAST598

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0135393.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili19 – 46Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

InParanoidiB4KEM5.
KOiK01283.
OrthoDBiEOG091G033S.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

B4KEM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKLICVALV AMLSLTHALV KEEIQAKEYL ENLNKELARR TNIETEASWA
60 70 80 90 100
YGSNINEENE KRKNEVSAEL AKFMKEVSVD IQKFNWRSYQ NEDIKRQFKS
110 120 130 140 150
LSKLGYAALP EADYAEFLEA VSSMESNFAK VKVCDYKDNT KCDLSLEPEI
160 170 180 190 200
EEVITKSRDP EELKHYWVQF YAKAGTAVRP QFERYVELNT KAAKLNNFTS
210 220 230 240 250
GAEVWLDEYE DETFEKQLED IFAEIRPLYE QVHGYVRYRL RQHYGDTVVP
260 270 280 290 300
EKGPLPMHLL GNMWAQQWSD IADLVSPFPD KPLVDVTAEM VKQGYTPLKM
310 320 330 340 350
FQMGDDFFTS MNLTKLPQEF WDKSIIEKPT DGRDLVCHAS AWDFYLQNDV
360 370 380 390 400
RIKQCTQVTQ NQLFTVHHEL GHIQYFLQYQ HLPFVYRTGA NPGFHEAVGD
410 420 430 440 450
VLSLSVSTPK HLEKINLLHN FVLDEEARIN QLFLTALDKI VFLPFAFTMD
460 470 480 490 500
KYRWSLFRGE VEKSKWNCAF WKLREEYSGI EPPVVRTEKD FDAPAKYHIS
510 520 530 540 550
ADVEYLRYLV SFIIQFQFYK SACIKAGQYD PKNPALPLDN CDIYGSVEAG
560 570 580 590 600
AAFHNMLSLG ASKPWPDALE AFNGERIMSG KAIAEYFEPL RVWLEAENIK
610
NNVHIGWTAS DKCVSA
Length:616
Mass (Da):71,288
Last modified:January 20, 2016 - v2
Checksum:iC1B8EE5640725095
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933807 Genomic DNA. Translation: EDW11904.2.
CH933807 Genomic DNA. Translation: KRG02967.1.
RefSeqiXP_002002462.2. XM_002002426.2.
XP_015020674.1. XM_015165188.1.

Genome annotation databases

EnsemblMetazoaiFBtr0163361; FBpp0161853; FBgn0135393.
GeneIDi6576473.
KEGGidmo:Dmoj_GI12636.

Similar proteinsi

Entry informationi

Entry nameiB4KEM5_DROMO
AccessioniPrimary (citable) accession number: B4KEM5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: January 20, 2016
Last modified: August 30, 2017
This is version 52 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported