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B4KAY0

- B4KAY0_DROMO

UniProt

B4KAY0 - B4KAY0_DROMO

Protein

DNA ligase

Gene

Dmoj\GI24375

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dmoj\GI24375Imported
    ORF Names:Dmoj_GI24375Imported, GI24375Imported
    OrganismiDrosophila mojavensis (Fruit fly)Imported
    Taxonomic identifieri7230 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
    ProteomesiUP000009192: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0147098. Dmoj\GI24375.

    Structurei

    3D structure databases

    ProteinModelPortaliB4KAY0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    InParanoidiB4KAY0.
    KOiK10776.
    OrthoDBiEOG7BKCT2.
    PhylomeDBiB4KAY0.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4KAY0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSKHVENED NKLDTFRRVC DEIAAESSYL RKVEKLELFF KKGSSGAGFE    50
    GDLLQWVQFL IPDSTQRVYN LQNKALLKLF ARIFHVDQQE MHLDLEQDGD 100
    ISETLRKHFA TSSKLKPQTQ SKLYLHEVEK MLCQLEQRTK EDEQTEVLQK 150
    LCKQATDLDL RTFIRLIKQD LRINARARHI LDAFGPQAYP AYQSSRDLAA 200
    IVQNFAGKEG TSLKTPIKAT AKKAKKDTSA IQVMTPISPM LANACKSVEE 250
    AFKKNPGGLY SEIKYDGERV QIHKKGAEFK FFSRNLKPVM DHKIKDLKDY 300
    IPRAFPGAGD MILDSEIILV DTETGALLPF GTLGAHKKHT YANASICLFV 350
    FDCLLYDGDD LTQLAFCKRR EILEQNIQPI KSHVQLSESE FLKTKNELAL 400
    MTAKVLQANL EGVVLKSPSS TYQPGKRNWL KVKKDYLFGG KMADTADLVV 450
    LGAWYGSGKK GGVLSIFLMG CYDARDHLWK TVTKVHSGLD DATNDEIHEE 500
    LMKLTKRADA NNIPNWLHCK KALIPDVLAK TPEKMPVWEI TGAEFTQSEA 550
    HTAGGISIRF PRITRLRSDK CAKEANDLAH LEQLYAASKN NVNVDLLLAN 600
    CNADNDDAQT NGLKLEKTPQ KGKGSKETAS SSKKGKRSKS GGSDDEQATP 650
    SKGPRKLAKV EPSAAASKGS LMDFFKPKKT TPAVKVESKS SEDVKAEVKG 700
    EVSNLFRGQV AYFAADAAQS KHKDAFIRNG GILSENSREA NLVFHSTTKN 750
    VNLAELRPLY RRSCRHLSVK WLEESLQAKK LQPYPLYAVV LKA 793
    Length:793
    Mass (Da):88,615
    Last modified:September 23, 2008 - v1
    Checksum:i51A29C5F515A547E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH933806 Genomic DNA. Translation: EDW14658.1.
    RefSeqiXP_001999197.1. XM_001999161.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0175100; FBpp0173592; FBgn0147098.
    GeneIDi6573106.
    KEGGidmo:Dmoj_GI24375.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH933806 Genomic DNA. Translation: EDW14658.1 .
    RefSeqi XP_001999197.1. XM_001999161.1.

    3D structure databases

    ProteinModelPortali B4KAY0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0175100 ; FBpp0173592 ; FBgn0147098 .
    GeneIDi 6573106.
    KEGGi dmo:Dmoj_GI24375.

    Organism-specific databases

    FlyBasei FBgn0147098. Dmoj\GI24375.

    Phylogenomic databases

    InParanoidi B4KAY0.
    KOi K10776.
    OrthoDBi EOG7BKCT2.
    PhylomeDBi B4KAY0.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15081-1352.22Imported.

    Entry informationi

    Entry nameiB4KAY0_DROMO
    AccessioniPrimary (citable) accession number: B4KAY0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3