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B4KAY0

- B4KAY0_DROMO

UniProt

B4KAY0 - B4KAY0_DROMO

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Protein

DNA ligase

Gene
Dmoj\GI24375, Dmoj_GI24375, GI24375
Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dmoj\GI24375Imported
ORF Names:Dmoj_GI24375Imported, GI24375Imported
OrganismiDrosophila mojavensis (Fruit fly)
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000009192: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0147098. Dmoj\GI24375.

Structurei

3D structure databases

ProteinModelPortaliB4KAY0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiB4KAY0.
KOiK10776.
OrthoDBiEOG7BKCT2.
PhylomeDBiB4KAY0.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4KAY0-1 [UniParc]FASTAAdd to Basket

« Hide

MGSKHVENED NKLDTFRRVC DEIAAESSYL RKVEKLELFF KKGSSGAGFE    50
GDLLQWVQFL IPDSTQRVYN LQNKALLKLF ARIFHVDQQE MHLDLEQDGD 100
ISETLRKHFA TSSKLKPQTQ SKLYLHEVEK MLCQLEQRTK EDEQTEVLQK 150
LCKQATDLDL RTFIRLIKQD LRINARARHI LDAFGPQAYP AYQSSRDLAA 200
IVQNFAGKEG TSLKTPIKAT AKKAKKDTSA IQVMTPISPM LANACKSVEE 250
AFKKNPGGLY SEIKYDGERV QIHKKGAEFK FFSRNLKPVM DHKIKDLKDY 300
IPRAFPGAGD MILDSEIILV DTETGALLPF GTLGAHKKHT YANASICLFV 350
FDCLLYDGDD LTQLAFCKRR EILEQNIQPI KSHVQLSESE FLKTKNELAL 400
MTAKVLQANL EGVVLKSPSS TYQPGKRNWL KVKKDYLFGG KMADTADLVV 450
LGAWYGSGKK GGVLSIFLMG CYDARDHLWK TVTKVHSGLD DATNDEIHEE 500
LMKLTKRADA NNIPNWLHCK KALIPDVLAK TPEKMPVWEI TGAEFTQSEA 550
HTAGGISIRF PRITRLRSDK CAKEANDLAH LEQLYAASKN NVNVDLLLAN 600
CNADNDDAQT NGLKLEKTPQ KGKGSKETAS SSKKGKRSKS GGSDDEQATP 650
SKGPRKLAKV EPSAAASKGS LMDFFKPKKT TPAVKVESKS SEDVKAEVKG 700
EVSNLFRGQV AYFAADAAQS KHKDAFIRNG GILSENSREA NLVFHSTTKN 750
VNLAELRPLY RRSCRHLSVK WLEESLQAKK LQPYPLYAVV LKA 793
Length:793
Mass (Da):88,615
Last modified:September 23, 2008 - v1
Checksum:i51A29C5F515A547E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH933806 Genomic DNA. Translation: EDW14658.1.
RefSeqiXP_001999197.1. XM_001999161.1.

Genome annotation databases

EnsemblMetazoaiFBtr0175100; FBpp0173592; FBgn0147098.
GeneIDi6573106.
KEGGidmo:Dmoj_GI24375.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH933806 Genomic DNA. Translation: EDW14658.1 .
RefSeqi XP_001999197.1. XM_001999161.1.

3D structure databases

ProteinModelPortali B4KAY0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0175100 ; FBpp0173592 ; FBgn0147098 .
GeneIDi 6573106.
KEGGi dmo:Dmoj_GI24375.

Organism-specific databases

FlyBasei FBgn0147098. Dmoj\GI24375.

Phylogenomic databases

InParanoidi B4KAY0.
KOi K10776.
OrthoDBi EOG7BKCT2.
PhylomeDBi B4KAY0.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15081-1352.22.

Entry informationi

Entry nameiB4KAY0_DROMO
AccessioniPrimary (citable) accession number: B4KAY0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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