Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Hexokinase

Gene

Dmoj\GI22624

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:Dmoj\GI22624Imported
ORF Names:Dmoj_GI22624Imported, GI22624Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
ProteomesiUP000009192: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0145352. Dmoj\GI22624.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

InParanoidiB4KAK1.
KOiK00844.
OMAiFIAECLS.
OrthoDBiEOG7S21X5.
PhylomeDBiB4KAK1.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4KAK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEVRTLYPD AYKICQQFEI DQHKMEEIIL RMTREISMGL AKDTHSRATI
60 70 80 90 100
KCFVTYVQDL PTGRERGRYL ALDLGGTNFR VLLVTLESES TVNIDGKTYG
110 120 130 140 150
ISKELMEGSG VKLFDFIAQC LSDFCKDHKL ENANLSLGFT FSFPCKQLGI
160 170 180 190 200
DNGTLVAWTK GFKADGVVNK NVVELLREAI TRRGDLKVQV VAILNDTTGT
210 220 230 240 250
LMSCAFTRQN CKIGMIVGTG SNACYVEKTS NVEMFPGYQN SPKPHMIINC
260 270 280 290 300
EWGAFGDNGV LDFVRTRYDV EVDSHSMNPK KQIYEKCISG MYMGELVRYI
310 320 330 340 350
LVELMDRDVI FKGVKSQTLQ QRGKFDTRFI TEIESDEPGK FRNAAMVMDN
360 370 380 390 400
LGIRTSNEKD LMCLRYICET ISTRSAKLAA CGLVCLIRKM NVKDLAVGID
410 420 430 440 450
GSVYRFHPHY HRLLMQNMNL LLNGTVRFEL VLSEDGSGRG AALIAAVCAK

D
Length:451
Mass (Da):50,662
Last modified:September 23, 2008 - v1
Checksum:iC4DEAF5DA88BB59E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933806 Genomic DNA. Translation: EDW15714.1.
RefSeqiXP_002000253.1. XM_002000217.1.

Genome annotation databases

EnsemblMetazoaiFBtr0173349; FBpp0171841; FBgn0145352.
GeneIDi6574195.
KEGGidmo:Dmoj_GI22624.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933806 Genomic DNA. Translation: EDW15714.1.
RefSeqiXP_002000253.1. XM_002000217.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0173349; FBpp0171841; FBgn0145352.
GeneIDi6574195.
KEGGidmo:Dmoj_GI22624.

Organism-specific databases

FlyBaseiFBgn0145352. Dmoj\GI22624.

Phylogenomic databases

InParanoidiB4KAK1.
KOiK00844.
OMAiFIAECLS.
OrthoDBiEOG7S21X5.
PhylomeDBiB4KAK1.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15081-1352.22Imported.

Entry informationi

Entry nameiB4KAK1_DROMO
AccessioniPrimary (citable) accession number: B4KAK1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.