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B4JWY5

- B4JWY5_DROGR

UniProt

B4JWY5 - B4JWY5_DROGR

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Protein
Submitted name:

GH17848

Gene

Dgri\GH17848

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: InterPro
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. histone H3-K4 methylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GH17848Imported
Gene namesi
Name:Dgri\GH17848Imported
ORF Names:Dgri_GH17848Imported, GH17848Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
ProteomesiUP000001070: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0125317. Dgri\GH17848.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0151754.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG2940.
InParanoidiB4JWY5.
KOiK09188.
OMAiSKKMSLQ.
OrthoDBiEOG7QZG8S.
PhylomeDBiB4JWY5.

Family and domain databases

InterProiIPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR015722. Histone-lys_MeTfrase_Trr.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001965. Znf_PHD.
[Graphical view]
PANTHERiPTHR22884:SF297. PTHR22884:SF297. 1 hit.
PfamiPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4JWY5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNISKVTTSL AAAAAAAEKA KPERVTSATA ALSFNTITIQ KRSSVDDTDD
60 70 80 90 100
ANRKKLKRDI VICTPTTSLP AKQRVATSTT TISAAAAATV ASPASAAQLP
110 120 130 140 150
PPTTGTAAAA AASTTSTISV KSTTTTTDEP QFVSQANAKT EPAGSAAAAV
160 170 180 190 200
AAAADVCWEA RDDQIIVCEM SAIKSEESSG TASTPNTNTT NTNSNNPKQN
210 220 230 240 250
FASFTKKDAA GSSASSSSST ASIISIEPSA DQPHQNNNNS SSEQQQLLGK
260 270 280 290 300
TVSIDELEYV LLPATTTAEL NPATHETTQV TNNINSSSTI SSSSNNNNSS
310 320 330 340 350
SNNNIVVSNT TTTSIVKSAT HPGSYSLFSS AGATTATATA TTTLLNRVNL
360 370 380 390 400
NAKFKGQHLM VNAKKLAEVT QTTAKVSIGN KTISVPLLKP QILQSGQLMS
410 420 430 440 450
VSGATTAGGA TIVESKQQLT TTATSATLTT ALQQQQHQQQ QQQQQHLNLT
460 470 480 490 500
KLLKGTRKNP TTILSIANVQ IKPANAKIVT AKVVSKKMSL QFQQQQLQLQ
510 520 530 540 550
QQQQQQQQQQ QQHHQQQQQQ PSTGSIVTIT PTNSSQTFTM LEKQLDGGEQ
560 570 580 590 600
SEQQQQQQQH PKTITYSENI QKILLNKSKS LDGSDASSEF GKINSVVIKP
610 620 630 640 650
LDKNQLHCAS NINIFKQQQQ QQATGTAAND DNKATTAGGA QIFTRPIISL
660 670 680 690 700
QKNISLVVSK APMGQQKAKL LTTPATLQQF NALETETVTK LQLKPQTVKL
710 720 730 740 750
SSADKSDASE SDTKPKLLLV KQTTQLPPPP PPPESSSKDV NAEQPDHELL
760 770 780 790 800
SSKAQEKRLV TPSRVDDSNN ALLKQLLQNS ISSNANSNNS HNLQQISITS
810 820 830 840 850
APLSARKVIN VRAPSMGLVS SLEAQLARPV IPPVPTAVSS SNNSSTSSGG
860 870 880 890 900
SGSGSCNTIT TTTATMVAIS QAPSSSSNTP TPTNEPQKLL ELQPETKAAI
910 920 930 940 950
VTTTIATTTA AATTTAAVMA ATVAVAPPTT VAAAAAATVA VAAAPAPAAA
960 970 980 990 1000
APQLKQSVQI VSKETSFIST PVTAAQSTVV LPTVVNKLPP TLLVESSLKT
1010 1020 1030 1040 1050
EQQQQLPPPP PYELSTGNVS NVTISITTKP SKELSKLAKL EPLDDEPEKS
1060 1070 1080 1090 1100
APTMTTPSAA THGDNWKMQD GHTSGSLMIC ETLKRKLPMQ QQQQQQQQQQ
1110 1120 1130 1140 1150
QHIEEKPALE LKTEILVNSN NKEHELIKTR IAAPPTIYEK LQLQQQQQQH
1160 1170 1180 1190 1200
LQQQQHQHLQ QHQQQQHLQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQPQQHQ
1210 1220 1230 1240 1250
MQMQLQQQQL QQQQIQQLQH QQQHQQQHQQ QHQQQHQQQH QQQQQQQQQQ
1260 1270 1280 1290 1300
QQQQQQQQQQ QQQHIQQQLQ QQLHHQQQQQ QQSMPATAQA TLPEPKAVEQ
1310 1320 1330 1340 1350
RKRRKRETQK PRRSNANSAA GAAAAAAAAS AAAAAAANSL KDMPGTLPAG
1360 1370 1380 1390 1400
AVVQLANVTT NSQLGGQMVA GGHLGAGGSG AGSMGSPMLK KRVRKFSKVE
1410 1420 1430 1440 1450
EDHDAFTDKL MTHIRQMQPL QVLEPLLNRN FLIGGGAGFG NGAGGGKLKA
1460 1470 1480 1490 1500
ISRALQLQRQ LDDNNADGSG SGGGSGSGGD IDCDQLLGRF GNVRHPSIKS
1510 1520 1530 1540 1550
LYDSERFGGS SEPSSCNSTS ANASGSSSSS SSSSGAAMST IQNDFYDQEF
1560 1570 1580 1590 1600
SSHIQRNPRE RLLRLISAVR DCNLETTELV EQLQQQQHHQ QQSSNMRLDG
1610 1620 1630 1640 1650
AVAWARHSRY PGLVLLNTNI NQRCAPGRMS PIALSMEAST MRPPVSQLMR
1660 1670 1680 1690 1700
SCAEELRKVQ QLDLGLTVTA PAATAAATNT ATIAIGSSST STGIVSSNNS
1710 1720 1730 1740 1750
SNNNNNNNNN NNNNNYQQKN QNVILSLHPS ATDNIAGVLR DLANLLHLTP
1760 1770 1780 1790 1800
ALTCKLIEAN NTAADKTDKQ PGETETESDS ELGDESGQGQ GHRRGRGAAA
1810 1820 1830 1840 1850
AAAATPTSQG NLRKILTGQR KLCRCCGSAI AAFGLRVPHQ NVPEEQPSPM
1860 1870 1880 1890 1900
LARLRALLPR QSPPSAFVYF CNRSCFTQYK YRGNDEPIDD ESLTIDRDMT
1910 1920 1930 1940 1950
ATSSTATATA TSTATATASQ HVIPIDKAEE DVDMEQQQPP QHLQQQQQQQ
1960 1970 1980 1990 2000
QPSQDLTATA TATLPVKRKC IIKCYSADCF ATSTDRSAHR PETDAATSNN
2010 2020 2030 2040 2050
TVWERDALGA HEDTRQCVFC NQRGDGQADG PSRLLNFDVD KWVHLNCALW
2060 2070 2080 2090 2100
SNDVFETVSG ALMNFPTALQ AGLNQACVAC HQLGATIKCF KSRCNSLYHL
2110 2120 2130 2140 2150
PCAIKEECVF YKDKSVHCST HASSSLASAA DNELSSFVVH RRVFVDRDRD
2160 2170 2180 2190 2200
ENRQVATVMH YSELTNLLRV GNMTFLNVGQ LLPHQLEAFH TSHYIYPIGY
2210 2220 2230 2240 2250
KVSRYYWCTR RPNRRCRYVC SIAEVGCRPE FRIQVHEGHD KEPDREYRDS
2260 2270 2280 2290 2300
TPSGVWQQIL QPIQRLRQVH KLLQLFPQHI SGEDLFGLTE PAIVRILESL
2310 2320 2330 2340 2350
PGIETLTDYR FKYGRNPLLE FPLAINPSGA ARTEPKQRQL LVWRKPHTQR
2360 2370 2380 2390 2400
TAGSCTTQRM ANSAAIAGEV ACPYSKQFVH SKSSQYKKMK QEWRNNVYLA
2410 2420 2430 2440 2450
RSKIQGLGLY AARDIEKHTM IIEYIGEVIR TEVSEIREKQ YESKNRGIYM
2460 2470 2480 2490 2500
FRLDEDRVVD ATLSGGLARY INHSCNPNCV TEIVEVDRDV RIIIFAKRKI
2510 2520 2530
YRGEELSYDY KFDIEDESHK IPCACGAPNC RKWMN
Length:2,535
Mass (Da):275,781
Last modified:September 23, 2008 - v1
Checksum:iA709D15C4925541C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH916376 Genomic DNA. Translation: EDV95261.1.
RefSeqiXP_001995609.1. XM_001995573.1.

Genome annotation databases

EnsemblMetazoaiFBtr0153262; FBpp0151754; FBgn0125317.
GeneIDi6569291.
KEGGidgr:Dgri_GH17848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH916376 Genomic DNA. Translation: EDV95261.1 .
RefSeqi XP_001995609.1. XM_001995573.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7222.FBpp0151754.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0153262 ; FBpp0151754 ; FBgn0125317 .
GeneIDi 6569291.
KEGGi dgr:Dgri_GH17848.

Organism-specific databases

FlyBasei FBgn0125317. Dgri\GH17848.

Phylogenomic databases

eggNOGi COG2940.
InParanoidi B4JWY5.
KOi K09188.
OMAi SKKMSLQ.
OrthoDBi EOG7QZG8S.
PhylomeDBi B4JWY5.

Family and domain databases

InterProi IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR015722. Histone-lys_MeTfrase_Trr.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001965. Znf_PHD.
[Graphical view ]
PANTHERi PTHR22884:SF297. PTHR22884:SF297. 1 hit.
Pfami PF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15287-2541.00Imported.

Entry informationi

Entry nameiB4JWY5_DROGR
AccessioniPrimary (citable) accession number: B4JWY5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3