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B4JWY5

- B4JWY5_DROGR

UniProt

B4JWY5 - B4JWY5_DROGR

Protein
Submitted name:

GH17848

Gene

Dgri\GH17848

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

    GO - Molecular functioni

    1. histone-lysine N-methyltransferase activity Source: InterPro
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. histone H3-K4 methylation Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotation, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    GH17848Imported
    Gene namesi
    Name:Dgri\GH17848Imported
    ORF Names:Dgri_GH17848Imported, GH17848Imported
    OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
    Taxonomic identifieri7222 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
    ProteomesiUP000001070: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0125317. Dgri\GH17848.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi7222.FBpp0151754.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains SET domain.SAAS annotation
    Contains post-SET domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG2940.
    InParanoidiB4JWY5.
    KOiK09188.
    OMAiSKKMSLQ.
    OrthoDBiEOG7QZG8S.
    PhylomeDBiB4JWY5.

    Family and domain databases

    InterProiIPR003889. FYrich_C.
    IPR003888. FYrich_N.
    IPR015722. Histone-lys_MeTfrase_Trr.
    IPR003616. Post-SET_dom.
    IPR001214. SET_dom.
    IPR001965. Znf_PHD.
    [Graphical view]
    PANTHERiPTHR22884:SF297. PTHR22884:SF297. 1 hit.
    PfamiPF05965. FYRC. 1 hit.
    PF05964. FYRN. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00542. FYRC. 1 hit.
    SM00541. FYRN. 1 hit.
    SM00249. PHD. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    PROSITEiPS51543. FYRC. 1 hit.
    PS51542. FYRN. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4JWY5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNISKVTTSL AAAAAAAEKA KPERVTSATA ALSFNTITIQ KRSSVDDTDD     50
    ANRKKLKRDI VICTPTTSLP AKQRVATSTT TISAAAAATV ASPASAAQLP 100
    PPTTGTAAAA AASTTSTISV KSTTTTTDEP QFVSQANAKT EPAGSAAAAV 150
    AAAADVCWEA RDDQIIVCEM SAIKSEESSG TASTPNTNTT NTNSNNPKQN 200
    FASFTKKDAA GSSASSSSST ASIISIEPSA DQPHQNNNNS SSEQQQLLGK 250
    TVSIDELEYV LLPATTTAEL NPATHETTQV TNNINSSSTI SSSSNNNNSS 300
    SNNNIVVSNT TTTSIVKSAT HPGSYSLFSS AGATTATATA TTTLLNRVNL 350
    NAKFKGQHLM VNAKKLAEVT QTTAKVSIGN KTISVPLLKP QILQSGQLMS 400
    VSGATTAGGA TIVESKQQLT TTATSATLTT ALQQQQHQQQ QQQQQHLNLT 450
    KLLKGTRKNP TTILSIANVQ IKPANAKIVT AKVVSKKMSL QFQQQQLQLQ 500
    QQQQQQQQQQ QQHHQQQQQQ PSTGSIVTIT PTNSSQTFTM LEKQLDGGEQ 550
    SEQQQQQQQH PKTITYSENI QKILLNKSKS LDGSDASSEF GKINSVVIKP 600
    LDKNQLHCAS NINIFKQQQQ QQATGTAAND DNKATTAGGA QIFTRPIISL 650
    QKNISLVVSK APMGQQKAKL LTTPATLQQF NALETETVTK LQLKPQTVKL 700
    SSADKSDASE SDTKPKLLLV KQTTQLPPPP PPPESSSKDV NAEQPDHELL 750
    SSKAQEKRLV TPSRVDDSNN ALLKQLLQNS ISSNANSNNS HNLQQISITS 800
    APLSARKVIN VRAPSMGLVS SLEAQLARPV IPPVPTAVSS SNNSSTSSGG 850
    SGSGSCNTIT TTTATMVAIS QAPSSSSNTP TPTNEPQKLL ELQPETKAAI 900
    VTTTIATTTA AATTTAAVMA ATVAVAPPTT VAAAAAATVA VAAAPAPAAA 950
    APQLKQSVQI VSKETSFIST PVTAAQSTVV LPTVVNKLPP TLLVESSLKT 1000
    EQQQQLPPPP PYELSTGNVS NVTISITTKP SKELSKLAKL EPLDDEPEKS 1050
    APTMTTPSAA THGDNWKMQD GHTSGSLMIC ETLKRKLPMQ QQQQQQQQQQ 1100
    QHIEEKPALE LKTEILVNSN NKEHELIKTR IAAPPTIYEK LQLQQQQQQH 1150
    LQQQQHQHLQ QHQQQQHLQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQPQQHQ 1200
    MQMQLQQQQL QQQQIQQLQH QQQHQQQHQQ QHQQQHQQQH QQQQQQQQQQ 1250
    QQQQQQQQQQ QQQHIQQQLQ QQLHHQQQQQ QQSMPATAQA TLPEPKAVEQ 1300
    RKRRKRETQK PRRSNANSAA GAAAAAAAAS AAAAAAANSL KDMPGTLPAG 1350
    AVVQLANVTT NSQLGGQMVA GGHLGAGGSG AGSMGSPMLK KRVRKFSKVE 1400
    EDHDAFTDKL MTHIRQMQPL QVLEPLLNRN FLIGGGAGFG NGAGGGKLKA 1450
    ISRALQLQRQ LDDNNADGSG SGGGSGSGGD IDCDQLLGRF GNVRHPSIKS 1500
    LYDSERFGGS SEPSSCNSTS ANASGSSSSS SSSSGAAMST IQNDFYDQEF 1550
    SSHIQRNPRE RLLRLISAVR DCNLETTELV EQLQQQQHHQ QQSSNMRLDG 1600
    AVAWARHSRY PGLVLLNTNI NQRCAPGRMS PIALSMEAST MRPPVSQLMR 1650
    SCAEELRKVQ QLDLGLTVTA PAATAAATNT ATIAIGSSST STGIVSSNNS 1700
    SNNNNNNNNN NNNNNYQQKN QNVILSLHPS ATDNIAGVLR DLANLLHLTP 1750
    ALTCKLIEAN NTAADKTDKQ PGETETESDS ELGDESGQGQ GHRRGRGAAA 1800
    AAAATPTSQG NLRKILTGQR KLCRCCGSAI AAFGLRVPHQ NVPEEQPSPM 1850
    LARLRALLPR QSPPSAFVYF CNRSCFTQYK YRGNDEPIDD ESLTIDRDMT 1900
    ATSSTATATA TSTATATASQ HVIPIDKAEE DVDMEQQQPP QHLQQQQQQQ 1950
    QPSQDLTATA TATLPVKRKC IIKCYSADCF ATSTDRSAHR PETDAATSNN 2000
    TVWERDALGA HEDTRQCVFC NQRGDGQADG PSRLLNFDVD KWVHLNCALW 2050
    SNDVFETVSG ALMNFPTALQ AGLNQACVAC HQLGATIKCF KSRCNSLYHL 2100
    PCAIKEECVF YKDKSVHCST HASSSLASAA DNELSSFVVH RRVFVDRDRD 2150
    ENRQVATVMH YSELTNLLRV GNMTFLNVGQ LLPHQLEAFH TSHYIYPIGY 2200
    KVSRYYWCTR RPNRRCRYVC SIAEVGCRPE FRIQVHEGHD KEPDREYRDS 2250
    TPSGVWQQIL QPIQRLRQVH KLLQLFPQHI SGEDLFGLTE PAIVRILESL 2300
    PGIETLTDYR FKYGRNPLLE FPLAINPSGA ARTEPKQRQL LVWRKPHTQR 2350
    TAGSCTTQRM ANSAAIAGEV ACPYSKQFVH SKSSQYKKMK QEWRNNVYLA 2400
    RSKIQGLGLY AARDIEKHTM IIEYIGEVIR TEVSEIREKQ YESKNRGIYM 2450
    FRLDEDRVVD ATLSGGLARY INHSCNPNCV TEIVEVDRDV RIIIFAKRKI 2500
    YRGEELSYDY KFDIEDESHK IPCACGAPNC RKWMN 2535
    Length:2,535
    Mass (Da):275,781
    Last modified:September 23, 2008 - v1
    Checksum:iA709D15C4925541C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916376 Genomic DNA. Translation: EDV95261.1.
    RefSeqiXP_001995609.1. XM_001995573.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0153262; FBpp0151754; FBgn0125317.
    GeneIDi6569291.
    KEGGidgr:Dgri_GH17848.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916376 Genomic DNA. Translation: EDV95261.1 .
    RefSeqi XP_001995609.1. XM_001995573.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7222.FBpp0151754.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0153262 ; FBpp0151754 ; FBgn0125317 .
    GeneIDi 6569291.
    KEGGi dgr:Dgri_GH17848.

    Organism-specific databases

    FlyBasei FBgn0125317. Dgri\GH17848.

    Phylogenomic databases

    eggNOGi COG2940.
    InParanoidi B4JWY5.
    KOi K09188.
    OMAi SKKMSLQ.
    OrthoDBi EOG7QZG8S.
    PhylomeDBi B4JWY5.

    Family and domain databases

    InterProi IPR003889. FYrich_C.
    IPR003888. FYrich_N.
    IPR015722. Histone-lys_MeTfrase_Trr.
    IPR003616. Post-SET_dom.
    IPR001214. SET_dom.
    IPR001965. Znf_PHD.
    [Graphical view ]
    PANTHERi PTHR22884:SF297. PTHR22884:SF297. 1 hit.
    Pfami PF05965. FYRC. 1 hit.
    PF05964. FYRN. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00542. FYRC. 1 hit.
    SM00541. FYRN. 1 hit.
    SM00249. PHD. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    PROSITEi PS51543. FYRC. 1 hit.
    PS51542. FYRN. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15287-2541.00Imported.

    Entry informationi

    Entry nameiB4JWY5_DROGR
    AccessioniPrimary (citable) accession number: B4JWY5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3