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Protein

DNA ligase

Gene

Dgri\GH20153

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dgri\GH20153Imported
ORF Names:Dgri_GH20153Imported, GH20153Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
Proteomesi
  • UP000001070 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0127617 Dgri\GH20153

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0154059

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini342 – 476DNA_LIGASE_A3InterPro annotationAdd BLAST135
Domaini707 – 795BRCTInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4437 Eukaryota
COG1793 LUCA
InParanoidiB4JRF5
KOiK10776
OMAiDCIYFND
OrthoDBiEOG091G0XBU
PhylomeDBiB4JRF5

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

B4JRF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSKQAQNED NKLDTFRHIC DEIAGESSYL RKVEKLEHFF KKGSSGSGFQ
60 70 80 90 100
GDTLQWVQFL IPGATQRVYN LQNKALLKLF ARILHVDQQQ MNLDLEQDGD
110 120 130 140 150
ISETLRKHFA GSSKLKPQAQ SKLYLHEVET LLCQLEQRTK EDEQTEVLHA
160 170 180 190 200
LCKQATDLDL RTFIRLIKQD LRINARARHI LDAFGPQAYP AYQSSRDLTA
210 220 230 240 250
IVENFAGSQD TSTAPKTPAK AAGGKKMKVA SSGIQVMTPV SPMLANACKS
260 270 280 290 300
VEEAFKKNPD GLYSEIKYDG ERVQIHKQGD EFKFFSRNLK PVMDHKIKDL
310 320 330 340 350
KDYIPRAFPG ADDMILDSEI ILVDTETGSL LPFGTLGAHK KHTFENASVC
360 370 380 390 400
LFVFDCLLYD GDDLTQVEFR KRREILEKNI KPIKSHVQLS ESEFLKTKKE
410 420 430 440 450
LALMTAKVLQ ANLEGVVLKN PAGTYQPGKR NWLKVKKDYL FGGKMADTAD
460 470 480 490 500
LVVLGAWYGS GKKGGVLSIF LMGCFDARDH LWKTVTKVHS GLDDVTNDDV
510 520 530 540 550
HEALMKLTDR ADANKIPSWL LCKKALVPDV LAKVPEQMPV WEITGAEFTQ
560 570 580 590 600
SEAHTAAGIS IRFPRITRLR SDKSAMQAND LEHLEQLYAA SKQNVNVDLL
610 620 630 640 650
LANSEPDSND TLENKLKVEK TPTKSKTIKA SLTSSSKKAK RSKNDTDDEE
660 670 680 690 700
AAPSKGRSTR KMSKLEAPSS ASQGNLKDFF KPKAIKTEVK NEPTSNSSKS
710 720 730 740 750
PELLKSESSK LFSGLLANFS VDAAQSKYMD EFVRHGGTLT MNTQKASLVF
760 770 780 790
HDVTRSVDLT QLRPLYHRSC RHLSVKWLET SIRAKTLQPY PLYALILKS
Length:799
Mass (Da):89,446
Last modified:September 23, 2008 - v1
Checksum:i0B8C04D429E52EE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916373 Genomic DNA Translation: EDV94345.1
RefSeqiXP_001993609.1, XM_001993573.1

Genome annotation databases

EnsemblMetazoaiFBtr0457896; FBpp0408401; FBgn0127617
GeneIDi6567229
KEGGidgr:Dgri_GH20153

Similar proteinsi

Entry informationi

Entry nameiB4JRF5_DROGR
AccessioniPrimary (citable) accession number: B4JRF5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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