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B4JRF5

- B4JRF5_DROGR

UniProt

B4JRF5 - B4JRF5_DROGR

Protein

DNA ligase

Gene

Dgri\GH20153

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dgri\GH20153Imported
    ORF Names:Dgri_GH20153Imported, GH20153Imported
    OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
    Taxonomic identifieri7222 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
    ProteomesiUP000001070: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0127617. Dgri\GH20153.

    Interactioni

    Protein-protein interaction databases

    STRINGi7222.FBpp0154059.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    InParanoidiB4JRF5.
    KOiK10776.
    OMAiNEDNKLD.
    OrthoDBiEOG7BKCT2.
    PhylomeDBiB4JRF5.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4JRF5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSKQAQNED NKLDTFRHIC DEIAGESSYL RKVEKLEHFF KKGSSGSGFQ    50
    GDTLQWVQFL IPGATQRVYN LQNKALLKLF ARILHVDQQQ MNLDLEQDGD 100
    ISETLRKHFA GSSKLKPQAQ SKLYLHEVET LLCQLEQRTK EDEQTEVLHA 150
    LCKQATDLDL RTFIRLIKQD LRINARARHI LDAFGPQAYP AYQSSRDLTA 200
    IVENFAGSQD TSTAPKTPAK AAGGKKMKVA SSGIQVMTPV SPMLANACKS 250
    VEEAFKKNPD GLYSEIKYDG ERVQIHKQGD EFKFFSRNLK PVMDHKIKDL 300
    KDYIPRAFPG ADDMILDSEI ILVDTETGSL LPFGTLGAHK KHTFENASVC 350
    LFVFDCLLYD GDDLTQVEFR KRREILEKNI KPIKSHVQLS ESEFLKTKKE 400
    LALMTAKVLQ ANLEGVVLKN PAGTYQPGKR NWLKVKKDYL FGGKMADTAD 450
    LVVLGAWYGS GKKGGVLSIF LMGCFDARDH LWKTVTKVHS GLDDVTNDDV 500
    HEALMKLTDR ADANKIPSWL LCKKALVPDV LAKVPEQMPV WEITGAEFTQ 550
    SEAHTAAGIS IRFPRITRLR SDKSAMQAND LEHLEQLYAA SKQNVNVDLL 600
    LANSEPDSND TLENKLKVEK TPTKSKTIKA SLTSSSKKAK RSKNDTDDEE 650
    AAPSKGRSTR KMSKLEAPSS ASQGNLKDFF KPKAIKTEVK NEPTSNSSKS 700
    PELLKSESSK LFSGLLANFS VDAAQSKYMD EFVRHGGTLT MNTQKASLVF 750
    HDVTRSVDLT QLRPLYHRSC RHLSVKWLET SIRAKTLQPY PLYALILKS 799
    Length:799
    Mass (Da):89,446
    Last modified:September 23, 2008 - v1
    Checksum:i0B8C04D429E52EE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916373 Genomic DNA. Translation: EDV94345.1.
    RefSeqiXP_001993609.1. XM_001993573.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0155567; FBpp0154059; FBgn0127617.
    GeneIDi6567229.
    KEGGidgr:Dgri_GH20153.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916373 Genomic DNA. Translation: EDV94345.1 .
    RefSeqi XP_001993609.1. XM_001993573.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7222.FBpp0154059.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0155567 ; FBpp0154059 ; FBgn0127617 .
    GeneIDi 6567229.
    KEGGi dgr:Dgri_GH20153.

    Organism-specific databases

    FlyBasei FBgn0127617. Dgri\GH20153.

    Phylogenomic databases

    eggNOGi COG1793.
    InParanoidi B4JRF5.
    KOi K10776.
    OMAi NEDNKLD.
    OrthoDBi EOG7BKCT2.
    PhylomeDBi B4JRF5.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15287-2541.00Imported.

    Entry informationi

    Entry nameiB4JRF5_DROGR
    AccessioniPrimary (citable) accession number: B4JRF5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3