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B4JRF5

- B4JRF5_DROGR

UniProt

B4JRF5 - B4JRF5_DROGR

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Protein
DNA ligase
Gene
Dgri\GH20153, Dgri_GH20153, GH20153
Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dgri\GH20153Imported
ORF Names:Dgri_GH20153Imported, GH20153Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
ProteomesiUP000001070: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0127617. Dgri\GH20153.

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0154059.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
InParanoidiB4JRF5.
KOiK10776.
OMAiNEDNKLD.
OrthoDBiEOG7BKCT2.
PhylomeDBiB4JRF5.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4JRF5-1 [UniParc]FASTAAdd to Basket

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MGSKQAQNED NKLDTFRHIC DEIAGESSYL RKVEKLEHFF KKGSSGSGFQ    50
GDTLQWVQFL IPGATQRVYN LQNKALLKLF ARILHVDQQQ MNLDLEQDGD 100
ISETLRKHFA GSSKLKPQAQ SKLYLHEVET LLCQLEQRTK EDEQTEVLHA 150
LCKQATDLDL RTFIRLIKQD LRINARARHI LDAFGPQAYP AYQSSRDLTA 200
IVENFAGSQD TSTAPKTPAK AAGGKKMKVA SSGIQVMTPV SPMLANACKS 250
VEEAFKKNPD GLYSEIKYDG ERVQIHKQGD EFKFFSRNLK PVMDHKIKDL 300
KDYIPRAFPG ADDMILDSEI ILVDTETGSL LPFGTLGAHK KHTFENASVC 350
LFVFDCLLYD GDDLTQVEFR KRREILEKNI KPIKSHVQLS ESEFLKTKKE 400
LALMTAKVLQ ANLEGVVLKN PAGTYQPGKR NWLKVKKDYL FGGKMADTAD 450
LVVLGAWYGS GKKGGVLSIF LMGCFDARDH LWKTVTKVHS GLDDVTNDDV 500
HEALMKLTDR ADANKIPSWL LCKKALVPDV LAKVPEQMPV WEITGAEFTQ 550
SEAHTAAGIS IRFPRITRLR SDKSAMQAND LEHLEQLYAA SKQNVNVDLL 600
LANSEPDSND TLENKLKVEK TPTKSKTIKA SLTSSSKKAK RSKNDTDDEE 650
AAPSKGRSTR KMSKLEAPSS ASQGNLKDFF KPKAIKTEVK NEPTSNSSKS 700
PELLKSESSK LFSGLLANFS VDAAQSKYMD EFVRHGGTLT MNTQKASLVF 750
HDVTRSVDLT QLRPLYHRSC RHLSVKWLET SIRAKTLQPY PLYALILKS 799
Length:799
Mass (Da):89,446
Last modified:September 23, 2008 - v1
Checksum:i0B8C04D429E52EE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH916373 Genomic DNA. Translation: EDV94345.1.
RefSeqiXP_001993609.1. XM_001993573.1.

Genome annotation databases

EnsemblMetazoaiFBtr0155567; FBpp0154059; FBgn0127617.
GeneIDi6567229.
KEGGidgr:Dgri_GH20153.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH916373 Genomic DNA. Translation: EDV94345.1 .
RefSeqi XP_001993609.1. XM_001993573.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7222.FBpp0154059.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0155567 ; FBpp0154059 ; FBgn0127617 .
GeneIDi 6567229.
KEGGi dgr:Dgri_GH20153.

Organism-specific databases

FlyBasei FBgn0127617. Dgri\GH20153.

Phylogenomic databases

eggNOGi COG1793.
InParanoidi B4JRF5.
KOi K10776.
OMAi NEDNKLD.
OrthoDBi EOG7BKCT2.
PhylomeDBi B4JRF5.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15287-2541.00.

Entry informationi

Entry nameiB4JRF5_DROGR
AccessioniPrimary (citable) accession number: B4JRF5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi