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Protein

Aldose 1-epimerase

Gene

Dgri\GH11905

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:Dgri\GH11905Imported
ORF Names:Dgri_GH11905Imported, GH11905Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
ProteomesiUP000001070: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0119384. Dgri\GH11905.

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0145811.

Structurei

3D structure databases

ProteinModelPortaliB4JLA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2017.
InParanoidiB4JLA6.
KOiK01785.
OMAiEDIFGIA.
OrthoDBiEOG7V7666.
PhylomeDBiB4JLA6.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

B4JLA6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKVVEDIFG IAINPFTERA QVVRRYTISN SSHLSVAIIQ LGASIQSIKC
60 70 80 90 100
PDAYHNVDDV VLGFDDIAGY EANRELKFGC MLGRVADRVA NGEFVMDRRK
110 120 130 140 150
VRVSQNFKNQ HQIDGGFIGF DRIIWDLHML RPDGITLRHT SADGHEGYPG
160 170 180 190 200
NLIVLLHFTM DDDNRFHIRI EARTDQPTPV NISNHCYFNM AGQKLGRKGL
210 220 230 240 250
LEHRLVIAAE HTIETGSESM PTGRFSPVDN TVYDMRVPAF IGDRLRQFEN
260 270 280 290 300
NPITAGFDVC YAIDKDFDAN ILHFVGRFLH PESGRFLDIH SNQPGMRFTT
310 320 330 340 350
ANNFPNDSHD EEPIMGKECA RYCQYSGFSV QMEKFPDTMN NLDFPTALIM
360 370 380
PSELYFHETI YTFGVHESWQ CCATTEELEE IGEHIVRYT
Length:389
Mass (Da):44,324
Last modified:September 23, 2008 - v1
Checksum:i1091EC3D0DB5ED11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916370 Genomic DNA. Translation: EDW00359.1.
RefSeqiXP_001991734.1. XM_001991698.1.

Genome annotation databases

EnsemblMetazoaiFBtr0147319; FBpp0145811; FBgn0119384.
GeneIDi6565492.
KEGGidgr:Dgri_GH11905.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916370 Genomic DNA. Translation: EDW00359.1.
RefSeqiXP_001991734.1. XM_001991698.1.

3D structure databases

ProteinModelPortaliB4JLA6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7222.FBpp0145811.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0147319; FBpp0145811; FBgn0119384.
GeneIDi6565492.
KEGGidgr:Dgri_GH11905.

Organism-specific databases

FlyBaseiFBgn0119384. Dgri\GH11905.

Phylogenomic databases

eggNOGiCOG2017.
InParanoidiB4JLA6.
KOiK01785.
OMAiEDIFGIA.
OrthoDBiEOG7V7666.
PhylomeDBiB4JLA6.

Enzyme and pathway databases

UniPathwayiUPA00242.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15287-2541.00Imported.

Entry informationi

Entry nameiB4JLA6_DROGR
AccessioniPrimary (citable) accession number: B4JLA6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 4, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.