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Protein

Angiotensin-converting enzyme

Gene

Dgri\GH10960

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.002

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dgri\GH10960Imported
ORF Names:Dgri_GH10960Imported, GH10960Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
Proteomesi
  • UP000001070 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0118441 Dgri\GH10960

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500281190819 – 632Angiotensin-converting enzymeSequence analysisAdd BLAST614

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0144866

Structurei

3D structure databases

ProteinModelPortaliB4JBC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690 Eukaryota
ENOG410XPJ3 LUCA
InParanoidiB4JBC5
KOiK01283
OMAiNCDIFGS
OrthoDBiEOG091G033S
PhylomeDBiB4JBC5

Family and domain databases

CDDicd06461 M2_ACE, 1 hit
InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Complete.

B4JBC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGLLLLPLL LTLAFVLSLP YGVADSNTCS ASVLQARRFF DQENSKLRER
60 70 80 90 100
YHAEYSAAYA YNTNVTEDNR RAMIAVYAES AKQNKLLAEA VKAGEYDESE
110 120 130 140 150
DAQIRRQARM LQDLGADALN ASDYLELKNA ISQMQSNYAT TTVCSYTNRT
160 170 180 190 200
DCSLTLEPHI QERLSNSRDP AELAWYWREW YDKAGTPMRE NFATYVRLTR
210 220 230 240 250
KAAHLNNYRS YADYWVHFYE DTDFERQLDA TYKALLPFYR QIHGYVRYRL
260 270 280 290 300
RQHYGPDVVP AEGNIPMHLL GNMWAQSWND VIDLFTPYPE KPFVDVKSEM
310 320 330 340 350
ERQEYSVQKL FQLGDQFFQS LGMRALPPTF WNASVLERPL DREVICHASA
360 370 380 390 400
WDFYQDSDVR IKMCTEVDTH YLYVVHHELG HIQYYLQYEQ QPAVFRGAPN
410 420 430 440 450
PGFHEAVGDV IALSVMSAKH LKSIGLTSNG RLDEKSRINE LFKQALSKIV
460 470 480 490 500
FLPFGYTMDK YRYAVFRNEL DENQWNCGFW QMRSEFGGVE PPMMRTDTDF
510 520 530 540 550
DPPAKYHIDA DVEYLRYFAA HIFQFQFHKA LCRLAGQYVP GDSRQTLDNC
560 570 580 590 600
DIFGSKKAGE AFKTFLSAGN SKHWKEVLEE LTGETEMDPA ALLEYFDPLY
610 620 630
QWLKLENSRL GVPLGWNETN KIPSSCCGAF ST
Length:632
Mass (Da):73,175
Last modified:September 23, 2008 - v1
Checksum:i039488362FB82DBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916368 Genomic DNA Translation: EDW02930.1
RefSeqiXP_001988063.1, XM_001988027.1

Genome annotation databases

EnsemblMetazoaiFBtr0459431; FBpp0409881; FBgn0118441
GeneIDi6561617
KEGGidgr:Dgri_GH10960

Similar proteinsi

Entry informationi

Entry nameiB4JBC5_DROGR
AccessioniPrimary (citable) accession number: B4JBC5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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