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Protein

Glycerol-3-phosphate dehydrogenase

Gene

Dgri\GH20102

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

FlavoproteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:Dgri\GH20102Imported
ORF Names:Dgri_GH20102Imported, GH20102Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
ProteomesiUP000001070: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0127566. Dgri\GH20102.

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0154008.

Structurei

3D structure databases

ProteinModelPortaliB4J6Y7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0578.
InParanoidiB4J6Y7.
KOiK00111.
OMAiVLRDIDC.
OrthoDBiEOG74TWZ2.
PhylomeDBiB4J6Y7.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
PROSITEiPS50222. EF_HAND_2. 1 hit.
PS00977. FAD_G3PDH_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4J6Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLFHVAVL AGSSMLGFSS TAVSQDGRSR MPQMKRELPS RSMNLDALRR
60 70 80 90 100
TEYDVLIIGG GAVGAGCALD AATRGLKTAL VEADDFGSGT SSKSSKLLHG
110 120 130 140 150
GLRDLDQAIA HLDGAAFRRV HSSLKERSNI ANLAPHLNQP VPIMLPLHHW
160 170 180 190 200
WQTPIYWAKL HLYHLMAPGP TKGFHYINSR EALELFPMMR RELFGAFIFY
210 220 230 240 250
EGQHDDARMC LAVVLTAARY GADVCNHMKV IDLLRDKQNM VVGAKAVDQL
260 270 280 290 300
TGKSYKIRAK IVINATGPLS DAISRLEDAE ATPQCIPSWA SHLVLPHYYC
310 320 330 340 350
PEQVGLFDPH PGHGSAIFFL PWLGHTLMGT AGERRDPMEG PHPTEMEVQY
360 370 380 390 400
LLDGIRHYIN PNFDVRRCDV LAVWGGYKPL PIESAELADS SLRNHVISLG
410 420 430 440 450
PGKMISIVGA TWTSFRLIAE QAIDAAIRIG GLEPLRLNSI TAKCCKLDGA
460 470 480 490 500
IGWSPNMFIR LVQDFGLERD VAKHLSDTYG SNAFKVAVCA NSCGGSWPIV
510 520 530 540 550
GKRLHTEFPY IEVEVRQGVK DYACTLVDMV ARRLRVAFLN VQVAEEILPR
560 570 580 590 600
LANEMAQQLN WSKKRKATEI REARKFLNTQ MGHSPAYEPA HLSIPIKLTV
610 620 630 640 650
NQVQKYAELF RNLDENNTGF VSISKSCAAM KSFGVKEIPV DLMHNVLRDI
660 670 680 690 700
DCHAPGKVNL YEFLLLMSAI VHGDTAYLHY ARMSLDQKHS AISHRRRGRF
710
EIPVARSGGG L
Length:711
Mass (Da):78,836
Last modified:September 23, 2008 - v1
Checksum:iE8DB905DF4C26F91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916367 Genomic DNA. Translation: EDW02068.1.
RefSeqiXP_001987201.1. XM_001987165.1.

Genome annotation databases

EnsemblMetazoaiFBtr0155516; FBpp0154008; FBgn0127566.
GeneIDi6559766.
KEGGidgr:Dgri_GH20102.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916367 Genomic DNA. Translation: EDW02068.1.
RefSeqiXP_001987201.1. XM_001987165.1.

3D structure databases

ProteinModelPortaliB4J6Y7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7222.FBpp0154008.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0155516; FBpp0154008; FBgn0127566.
GeneIDi6559766.
KEGGidgr:Dgri_GH20102.

Organism-specific databases

FlyBaseiFBgn0127566. Dgri\GH20102.

Phylogenomic databases

eggNOGiCOG0578.
InParanoidiB4J6Y7.
KOiK00111.
OMAiVLRDIDC.
OrthoDBiEOG74TWZ2.
PhylomeDBiB4J6Y7.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
PROSITEiPS50222. EF_HAND_2. 1 hit.
PS00977. FAD_G3PDH_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15287-2541.00Imported.

Entry informationi

Entry nameiB4J6Y7_DROGR
AccessioniPrimary (citable) accession number: B4J6Y7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 7, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.