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B4J642

- B4J642_DROGR

UniProt

B4J642 - B4J642_DROGR

Protein

DNA ligase

Gene

Dgri\GH20192

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dgri\GH20192Imported
    ORF Names:Dgri_GH20192Imported, GH20192Imported
    OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
    Taxonomic identifieri7222 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
    ProteomesiUP000001070: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0127656. Dgri\GH20192.

    Interactioni

    Protein-protein interaction databases

    STRINGi7222.FBpp0154098.

    Structurei

    3D structure databases

    ProteinModelPortaliB4J642.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    InParanoidiB4J642.
    KOiK10747.
    OMAiMVKMLEG.
    OrthoDBiEOG7RFTGN.
    PhylomeDBiB4J642.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4J642-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDEPMEPLPS KQKIISLTSD SNESEGTDIY NPSLELYHPI NHAYWRAEGV    50
    TPYLALARTF QVIEETKGRL KMIDILSNFF CSVMMVSPED LVPCVYLSIN 100
    QLAPAYEGLE LGVAETTLMK AICKATGRNL AHIKSQTQLI GDLGIVAEQS 150
    RVSQRMMFRP KPLNVRAVFA KLKEIANISG QSKITLVYDI FVACRLSEAR 200
    FFIRSLIGKL RIGIAEQSLL TALAIALVKK LHINDCKRID KVAEIYKDEI 250
    AETTLILKTT FCQCPNYDII IPAILKYDIE ELQERCPMHP GMPLRPMLAQ 300
    PTKGVHEVLE RFSGMHITCE WKYDGERAQI HLNEQGEISI FSRNSENNTP 350
    KYPDLIARSK PILKTEVKSY ILDSEIVAWD IERKQILPFQ ILSTRKRKNV 400
    DIDDIKVQVC VYIFDLLYIN GKSLVTQPLS ERRKILFEHF QEVEGEWKFA 450
    TALNTNDMDE VQQFLEESIK GNCEGLMVKT LDEEATYEIA KRSRNWLKLK 500
    KDYLSNVGDS LDLVVIGGYK GKGRRTGIYG GFLLACYDTD NEEYQTICKI 550
    GTGFTDEDLR QHSEFFSTNK LSEAKSYFRY DSSLEPDDWF EPCQVWEVKC 600
    ADLSLSPIHR AGIGIVDAER GISLRFPRFI RIRDDKSPEN ATDANQVAHM 650
    YSSQDVVKNN QKSSNSMDLE SDFY 674
    Length:674
    Mass (Da):76,917
    Last modified:September 23, 2008 - v1
    Checksum:i31302D18EA11CE00
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916367 Genomic DNA. Translation: EDW01900.1.
    RefSeqiXP_001987033.1. XM_001986997.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0155606; FBpp0154098; FBgn0127656.
    GeneIDi6559920.
    KEGGidgr:Dgri_GH20192.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916367 Genomic DNA. Translation: EDW01900.1 .
    RefSeqi XP_001987033.1. XM_001986997.1.

    3D structure databases

    ProteinModelPortali B4J642.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7222.FBpp0154098.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0155606 ; FBpp0154098 ; FBgn0127656 .
    GeneIDi 6559920.
    KEGGi dgr:Dgri_GH20192.

    Organism-specific databases

    FlyBasei FBgn0127656. Dgri\GH20192.

    Phylogenomic databases

    eggNOGi COG1793.
    InParanoidi B4J642.
    KOi K10747.
    OMAi MVKMLEG.
    OrthoDBi EOG7RFTGN.
    PhylomeDBi B4J642.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15287-2541.00Imported.

    Entry informationi

    Entry nameiB4J642_DROGR
    AccessioniPrimary (citable) accession number: B4J642
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3