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B4J642

- B4J642_DROGR

UniProt

B4J642 - B4J642_DROGR

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Protein

DNA ligase

Gene
Dgri\GH20192, Dgri_GH20192, GH20192
Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dgri\GH20192Imported
ORF Names:Dgri_GH20192Imported, GH20192Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
ProteomesiUP000001070: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0127656. Dgri\GH20192.

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0154098.

Structurei

3D structure databases

ProteinModelPortaliB4J642.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
InParanoidiB4J642.
KOiK10747.
OMAiMVKMLEG.
OrthoDBiEOG7RFTGN.
PhylomeDBiB4J642.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4J642-1 [UniParc]FASTAAdd to Basket

« Hide

MDEPMEPLPS KQKIISLTSD SNESEGTDIY NPSLELYHPI NHAYWRAEGV    50
TPYLALARTF QVIEETKGRL KMIDILSNFF CSVMMVSPED LVPCVYLSIN 100
QLAPAYEGLE LGVAETTLMK AICKATGRNL AHIKSQTQLI GDLGIVAEQS 150
RVSQRMMFRP KPLNVRAVFA KLKEIANISG QSKITLVYDI FVACRLSEAR 200
FFIRSLIGKL RIGIAEQSLL TALAIALVKK LHINDCKRID KVAEIYKDEI 250
AETTLILKTT FCQCPNYDII IPAILKYDIE ELQERCPMHP GMPLRPMLAQ 300
PTKGVHEVLE RFSGMHITCE WKYDGERAQI HLNEQGEISI FSRNSENNTP 350
KYPDLIARSK PILKTEVKSY ILDSEIVAWD IERKQILPFQ ILSTRKRKNV 400
DIDDIKVQVC VYIFDLLYIN GKSLVTQPLS ERRKILFEHF QEVEGEWKFA 450
TALNTNDMDE VQQFLEESIK GNCEGLMVKT LDEEATYEIA KRSRNWLKLK 500
KDYLSNVGDS LDLVVIGGYK GKGRRTGIYG GFLLACYDTD NEEYQTICKI 550
GTGFTDEDLR QHSEFFSTNK LSEAKSYFRY DSSLEPDDWF EPCQVWEVKC 600
ADLSLSPIHR AGIGIVDAER GISLRFPRFI RIRDDKSPEN ATDANQVAHM 650
YSSQDVVKNN QKSSNSMDLE SDFY 674
Length:674
Mass (Da):76,917
Last modified:September 23, 2008 - v1
Checksum:i31302D18EA11CE00
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH916367 Genomic DNA. Translation: EDW01900.1.
RefSeqiXP_001987033.1. XM_001986997.1.

Genome annotation databases

EnsemblMetazoaiFBtr0155606; FBpp0154098; FBgn0127656.
GeneIDi6559920.
KEGGidgr:Dgri_GH20192.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH916367 Genomic DNA. Translation: EDW01900.1 .
RefSeqi XP_001987033.1. XM_001986997.1.

3D structure databases

ProteinModelPortali B4J642.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7222.FBpp0154098.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0155606 ; FBpp0154098 ; FBgn0127656 .
GeneIDi 6559920.
KEGGi dgr:Dgri_GH20192.

Organism-specific databases

FlyBasei FBgn0127656. Dgri\GH20192.

Phylogenomic databases

eggNOGi COG1793.
InParanoidi B4J642.
KOi K10747.
OMAi MVKMLEG.
OrthoDBi EOG7RFTGN.
PhylomeDBi B4J642.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 15287-2541.00.

Entry informationi

Entry nameiB4J642_DROGR
AccessioniPrimary (citable) accession number: B4J642
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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