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B4IYU1

- B4IYU1_DROGR

UniProt

B4IYU1 - B4IYU1_DROGR

Protein

Aldose 1-epimerase

Gene

Dgri\GH16364

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.UniRule annotation

    Catalytic activityi

    Alpha-D-glucose = beta-D-glucose.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. aldose 1-epimerase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. hexose metabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotation

    Keywords - Biological processi

    Carbohydrate metabolismUniRule annotation

    Enzyme and pathway databases

    UniPathwayiUPA00242.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
    Alternative name(s):
    Galactose mutarotaseUniRule annotation
    Gene namesi
    Name:Dgri\GH16364Imported
    ORF Names:Dgri_GH16364Imported, GH16364Imported
    OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
    Taxonomic identifieri7222 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
    ProteomesiUP000001070: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0123835. Dgri\GH16364.

    Interactioni

    Protein-protein interaction databases

    STRINGi7222.FBpp0150270.

    Structurei

    3D structure databases

    ProteinModelPortaliB4IYU1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldose epimerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2017.
    InParanoidiB4IYU1.
    KOiK01785.
    OMAiLMRIRNT.
    OrthoDBiEOG7V7666.
    PhylomeDBiB4IYU1.

    Family and domain databases

    Gene3Di2.70.98.10. 1 hit.
    InterProiIPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view]
    PfamiPF01263. Aldose_epim. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005096. GALM. 1 hit.
    SUPFAMiSSF74650. SSF74650. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4IYU1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVRVIEDVFG IAVNPLTQKT EHVRRFTLST EKDMSVAILT LGAIIQSVKV    50
    PDFNGKLADV CLGYDDVAGY YRNQQSYFGA TLGRVANRVA HGHFKLCGKD 100
    VSITRNLKDR HHLHGGYVGF DSVIWDVVGI HKDGITLQHV SPDGHEGYPG 150
    EVTVNINFSL NEAGCFGMRI EARAKATTCI NISNHVYFNL AGHDTGRETL 200
    FQHMAMIKAN TIVDTDQEQL PTGKLMPVRN TPYDFSTLTN LGKRLNQVYR 250
    CPICGFDNNY CVNVDPNQVK LVARAVHPCT GRFMEVHTNQ PGLQFYTANS 300
    LPDEERGDIP NIGKDGAHYV KHGAFSMQTQ KYPDSMNNAS FPTVIINPGQ 350
    LYDHQVVFRF GACPKRI 367
    Length:367
    Mass (Da):40,859
    Last modified:September 23, 2008 - v1
    Checksum:i6BE847CA709E5D38
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916366 Genomic DNA. Translation: EDV96628.1.
    RefSeqiXP_001984280.1. XM_001984244.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0151778; FBpp0150270; FBgn0123835.
    GeneIDi6556681.
    KEGGidgr:Dgri_GH16364.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH916366 Genomic DNA. Translation: EDV96628.1 .
    RefSeqi XP_001984280.1. XM_001984244.1.

    3D structure databases

    ProteinModelPortali B4IYU1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7222.FBpp0150270.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0151778 ; FBpp0150270 ; FBgn0123835 .
    GeneIDi 6556681.
    KEGGi dgr:Dgri_GH16364.

    Organism-specific databases

    FlyBasei FBgn0123835. Dgri\GH16364.

    Phylogenomic databases

    eggNOGi COG2017.
    InParanoidi B4IYU1.
    KOi K01785.
    OMAi LMRIRNT.
    OrthoDBi EOG7V7666.
    PhylomeDBi B4IYU1.

    Enzyme and pathway databases

    UniPathwayi UPA00242 .

    Family and domain databases

    Gene3Di 2.70.98.10. 1 hit.
    InterProi IPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view ]
    Pfami PF01263. Aldose_epim. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005096. GALM. 1 hit.
    SUPFAMi SSF74650. SSF74650. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 15287-2541.00Imported.

    Entry informationi

    Entry nameiB4IYU1_DROGR
    AccessioniPrimary (citable) accession number: B4IYU1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3