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Protein

Histone deacetylase

Gene

Dsec\GM20078

Organism
Drosophila sechellia (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri493 – 554UBP-typePROSITE-ProRule annotationAdd BLAST62

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
Name:Dsec\GM20078Imported
ORF Names:Dsec_GM20078Imported, GM20078Imported
OrganismiDrosophila sechellia (Fruit fly)Imported
Taxonomic identifieri7238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000001292 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0174961. Dsec\GM20078.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB4ILG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini493 – 554UBP-typeInterPro annotationAdd BLAST62

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri493 – 554UBP-typePROSITE-ProRule annotationAdd BLAST62

Phylogenomic databases

KOiK11407.
OMAiFDCAVLA.
OrthoDBiEOG091G0210.
PhylomeDBiB4ILG3.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR037138. His_deacetylse_dom_sf.
IPR023696. Ureohydrolase_dom_sf.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PF02148. zf-UBP. 1 hit.
PRINTSiPR01270. HDASUPER.
SMARTiView protein in SMART
SM00290. ZnF_UBP. 1 hit.
SUPFAMiSSF52768. SSF52768. 1 hit.
PROSITEiView protein in PROSITE
PS50271. ZF_UBP. 1 hit.

Sequencei

Sequence statusi: Complete.

B4ILG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRARLQVLRA ENQAIGAVGE RCAMPYDAQM LLHCNLNDTG HPEQPSRIQH
60 70 80 90 100
IHKMHDDYGL LTQMKQLSAR AATTDEVCLA HTRAHVNTVR RLLGREPKEL
110 120 130 140 150
HDAAGIYNSV YLHPRTFDCA VLAAGSVLQA VDSVLRGESR SGICNVRPPG
160 170 180 190 200
HHAEQDHPHG FCIFNNVAIA AQYAIRDFGL ERVLIVDWDV HHGNGTQHIF
210 220 230 240 250
ESNPKVLYIS LHRYEHGSFF PKGPDGNFDV VGKGAGRGFN VNIPWNKKGM
260 270 280 290 300
GDLEYALAFQ QLVMPIAYEF NPQLVLVSAG FDAAIGDPLG GCKVTPEGYG
310 320 330 340 350
MLTHWLSALA SGRIIVCLEG GYNVNSISYA MTMCTKTLLG DPVPTPQLGA
360 370 380 390 400
TALQKPPTVA FQSCVESLQL CLQVQRNHWR SLEFVGRRLP RDPVVGENNN
410 420 430 440 450
EDFLTASLRH LNISNDDATV AASGPAVDRP DCGDERPSGS KPKVKVKTLS
460 470 480 490 500
DYLADNKEAL EQSEMFAVYP LKTCPHLRLL RPEEAPRSLD SRAECSVCGS
510 520 530 540 550
TGENWVCLSC RHVACGRYVN AHMEQHSVEE QHPLAMSTAD LSVWCYACSA
560 570 580 590 600
YVDHPRLYAY LNPLHVDKFQ EPMAWTHGCA WREDGCYATG PDGRDEDDEN
610
NDDDNVAGSS ICLRLERNN
Length:619
Mass (Da):68,428
Last modified:September 23, 2008 - v1
Checksum:i4D4E7101AE057F5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH480871 Genomic DNA. Translation: EDW53826.1.
RefSeqiXP_002044573.1. XM_002044537.1.

Genome annotation databases

EnsemblMetazoaiFBtr0203063; FBpp0201555; FBgn0174961.
GeneIDi6620365.
KEGGidse:Dsec_GM20078.

Similar proteinsi

Entry informationi

Entry nameiB4ILG3_DROSE
AccessioniPrimary (citable) accession number: B4ILG3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 22, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported