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B4IIM8

- B4IIM8_DROSE

UniProt

B4IIM8 - B4IIM8_DROSE

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Protein
Submitted name:

GM17444

Gene

Dsec\GM17444

Organism
Drosophila sechellia (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. chromatin binding Source: InterPro
  2. DNA binding Source: InterPro
  3. histone-lysine N-methyltransferase activity Source: InterPro
  4. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
GM17444Imported
Gene namesi
Name:Dsec\GM17444Imported
ORF Names:Dsec_GM17444Imported, GM17444Imported
OrganismiDrosophila sechellia (Fruit fly)Imported
Taxonomic identifieri7238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001292: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0172354. Dsec\GM17444.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

KOiK06101.
OrthoDBiEOG7ZPNJ4.
PhylomeDBiB4IIM8.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 3 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4IIM8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRRQQQRFWK RNAHKNPAET DSITDQSSQS KSIKSATQFS VQRSDTDGLR
60 70 80 90 100
MRISAIRPPS GVVATKKPPK SRKMSTHDTE SGCSEARNRV GSKKVKVKRK
110 120 130 140 150
KLASASGISK SDKVSKSKKS QISAFSSDSE DDLPLKVHQQ RAPRVLLSAI
160 170 180 190 200
IQAAQSASKP TLDIGISSSD NELPSLVQAA IKRVESDTED TTVEGSFRKA
210 220 230 240 250
AKDKNLPQYQ STLLQDFMEK TQMLGQTVNA KIAEEKVAKA KEETLVQTAV
260 270 280 290 300
PRKRRGRPKK VVPTVPVPGN SGPAINESAD SGVISTTSTT QSTTPSPKMQ
310 320 330 340 350
NENVVPTGSL PIASSSKPKI DMAYLDKRMY ATERVLYPPP RSKRRQNNKK
360 370 380 390 400
AACSSSNKEE LQLDPLWREI DVNKKFRLRS MSVGAASGTG ASTTICSKVL
410 420 430 440 450
AAKSGYVSDY GSVRHQRSSH NHNSGYKSDA SCKSRYSTKS CMSRRSRAKS
460 470 480 490 500
CGYRSDCKES GKSGLRMRRK RRASMLLKSS ADDPVEDQDI LQLAGLSLGQ
510 520 530 540 550
SSEESTEYIS KPSLKSLPTT SASKKYGEIN RYVTTGQYFG RGGSLTATNP
560 570 580 590 600
DNFISKMMNQ RKETPAPSKS SCKIKSRRSS AASMCSSYVS GVSRLRRRHR
610 620 630 640 650
RKSFSHNKSL NIDSKLLTEI EIITSTFNSR CRIQDDRLTG SSGKEKLLAD
660 670 680 690 700
ANKLQATLAA PSPAQQLTLN GGGSGSTLSK PLKRGLKKRK LSEPLVDFAM
710 720 730 740 750
LSASASGTPN GSGSSNGNTK RRHKKSQSND SSSPDDHKLP LKKRHYLLTP
760 770 780 790 800
GERPPAEVAF ANGKLNAEAW AAAAAAAKST ASTKSQAQFN ARSVKSALTP
810 820 830 840 850
KKRHLLEQPT SVSGAGSSAS NSPLRIVVDN NSISGGKLLD ISPSSLCSLK
860 870 880 890 900
QQRRGGAAKQ KVSAAKDLVQ LQSPAGSYPP PGVFEPSVEL EIQIPLGKLN
910 920 930 940 950
ESVITKAEVE SPLLSALDIK EDTKKEVGQR VVETLLHKTG GNLLLKRKRK
960 970 980 990 1000
KINRTGFPTV RRKKRKVSVE QQTTVVINGP EPEFDPDDEP LQSLRETRSS
1010 1020 1030 1040 1050
NSVNMQAPAN PSLDCERVPQ AGEARETFVA RTNQKAPRLS VVALERLQRP
1060 1070 1080 1090 1100
QTPARGRPRG RKPKNREQAG AAPLPPPKSE PEIRPAKKRG RQPKQPVLAE
1110 1120 1130 1140 1150
PPPTPPPQQK KNKIEPNIRL PDGIDPNTNF SCKIRLKRRK NLEAGTQPKK
1160 1170 1180 1190 1200
EKPIQTVTVE EIPPEIPVNQ EEIDAEAEAK RLDSIPLEHD PLPASESQNN
1210 1220 1230 1240 1250
GPQDYASCSE SSEDKASTTS LRKLSKVKKT YLVAGLFSNH YKQSLMPPPA
1260 1270 1280 1290 1300
KVNKKPGLEE QVGPASLLPP PPYCEKYLRR TEMDFELPYD IWWAYTNSKL
1310 1320 1330 1340 1350
PTRNVVPSWN YRKIRTNVYA ESVRPNLAGF DHPTCNCKDQ GEKSCLDNCL
1360 1370 1380 1390 1400
NRMVYTECSP SNCPAGEKCR NQKIQRHAVA PGVERFMTAD KGWGVRTKLP
1410 1420 1430 1440 1450
IAKGTYILEY VGEVVTEKEF KQRMASIYLN DTHHYCLHLD GGLVIDGQRM
1460 1470 1480 1490 1500
GSDCRFVNHS CEPNCEMQKW SVNGLSRMVL FAKRAIEEGE ELTYDYNFSL
1510 1520 1530 1540 1550
FNPSEGQPCR CNTPQCRGVI GGKSQRVKPL PAVEAKPAGD GLSGRNGRQR
1560 1570 1580 1590 1600
KQKAKKHAQR QAGKDISSAV AVAKLQPLSE KEEKLVRQFN TFLVRNFEKI
1610 1620 1630 1640 1650
RRCKDKRASA AAATASSPAL GATNGDIPGR RPSTPSSPSL AAQISALCSP
1660 1670 1680 1690 1700
RNIKTRGLTQ AVHDPELEKM AKMAVVLRDI CSAMETLKMS DLLTTVSSKK
1710 1720 1730 1740 1750
KKPIKTTLIG KVGATAATSK VEFRSIQVQV EQGHYKTPQE FDDHMQQLFV
1760 1770 1780 1790 1800
EAKQQHGDDE GKAKALQSLK DSYEQQKIAS YVQLVEILGD SESLQSFKPK
1810 1820 1830 1840 1850
EVLSPEEEAG KMAVKKSPGA KERDSPIVPL KVTPPPLLPV EASPDEDVIR
1860 1870 1880 1890 1900
CICGLYKDEG LMIQCAKCMV WQHTECTKAD IDADNYQCER CEPREVDREI
1910 1920 1930 1940 1950
PLEEFTEEGH RYYLSLMRGD LQVRQGDAVY VLRDIPIKDE SGKVLPTKKH
1960 1970 1980 1990 2000
TYETIGAIDY QECDIFRVEH LWKNELGKRF IFGHHFLRPH ETFHEPSRRF
2010 2020 2030 2040 2050
YPNEVVRVSL YEVVPIELVI GRCWVLDRTT FCKGRPMECN DEDHCYICEL
2060 2070 2080 2090 2100
RVDKTARFFS KAKANHPACT KSYAFRKFPE KIKISKSYAP HDVDPSLLKT
2110 2120 2130 2140 2150
RKQKTELELG AGQTTMHKVP GRQEQHQPKM VGRKHRGISG IPADATAVHV
2160 2170 2180 2190 2200
VTPMAPNKQM LKKRRSRLEN VLITMKLKCL DAQTAQEQPI DLSYLLSGRG
2210
ARQRKTQQSS SNSTVNST
Length:2,218
Mass (Da):245,662
Last modified:September 23, 2008 - v1
Checksum:i038880A5360B6BB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH480844 Genomic DNA. Translation: EDW49799.1.
RefSeqiXP_002043588.1. XM_002043552.1.

Genome annotation databases

EnsemblMetazoaiFBtr0200429; FBpp0198921; FBgn0172354.
GeneIDi6619372.
KEGGidse:Dsec_GM17444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH480844 Genomic DNA. Translation: EDW49799.1 .
RefSeqi XP_002043588.1. XM_002043552.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0200429 ; FBpp0198921 ; FBgn0172354 .
GeneIDi 6619372.
KEGGi dse:Dsec_GM17444.

Organism-specific databases

FlyBasei FBgn0172354. Dsec\GM17444.

Phylogenomic databases

KOi K06101.
OrthoDBi EOG7ZPNJ4.
PhylomeDBi B4IIM8.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF01426. BAH. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 3 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rob3c / Tucson 14021-0248.25Imported.

Entry informationi

Entry nameiB4IIM8_DROSE
AccessioniPrimary (citable) accession number: B4IIM8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 26, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3