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B4IIM8

- B4IIM8_DROSE

UniProt

B4IIM8 - B4IIM8_DROSE

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Protein
Submitted name: GM17444
Gene
Dsec\GM17444, Dsec_GM17444, GM17444
Organism
Drosophila sechellia (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. chromatin binding Source: InterPro
  3. histone-lysine N-methyltransferase activity Source: InterPro
  4. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
GM17444Imported
Gene namesi
Name:Dsec\GM17444Imported
ORF Names:Dsec_GM17444Imported, GM17444Imported
OrganismiDrosophila sechellia (Fruit fly)
Taxonomic identifieri7238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001292: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0172354. Dsec\GM17444.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Keywords - Domaini

Zinc-fingerSAAS annotations

Phylogenomic databases

KOiK06101.
OrthoDBiEOG7ZPNJ4.
PhylomeDBiB4IIM8.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 3 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4IIM8-1 [UniParc]FASTAAdd to Basket

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MRRQQQRFWK RNAHKNPAET DSITDQSSQS KSIKSATQFS VQRSDTDGLR     50
MRISAIRPPS GVVATKKPPK SRKMSTHDTE SGCSEARNRV GSKKVKVKRK 100
KLASASGISK SDKVSKSKKS QISAFSSDSE DDLPLKVHQQ RAPRVLLSAI 150
IQAAQSASKP TLDIGISSSD NELPSLVQAA IKRVESDTED TTVEGSFRKA 200
AKDKNLPQYQ STLLQDFMEK TQMLGQTVNA KIAEEKVAKA KEETLVQTAV 250
PRKRRGRPKK VVPTVPVPGN SGPAINESAD SGVISTTSTT QSTTPSPKMQ 300
NENVVPTGSL PIASSSKPKI DMAYLDKRMY ATERVLYPPP RSKRRQNNKK 350
AACSSSNKEE LQLDPLWREI DVNKKFRLRS MSVGAASGTG ASTTICSKVL 400
AAKSGYVSDY GSVRHQRSSH NHNSGYKSDA SCKSRYSTKS CMSRRSRAKS 450
CGYRSDCKES GKSGLRMRRK RRASMLLKSS ADDPVEDQDI LQLAGLSLGQ 500
SSEESTEYIS KPSLKSLPTT SASKKYGEIN RYVTTGQYFG RGGSLTATNP 550
DNFISKMMNQ RKETPAPSKS SCKIKSRRSS AASMCSSYVS GVSRLRRRHR 600
RKSFSHNKSL NIDSKLLTEI EIITSTFNSR CRIQDDRLTG SSGKEKLLAD 650
ANKLQATLAA PSPAQQLTLN GGGSGSTLSK PLKRGLKKRK LSEPLVDFAM 700
LSASASGTPN GSGSSNGNTK RRHKKSQSND SSSPDDHKLP LKKRHYLLTP 750
GERPPAEVAF ANGKLNAEAW AAAAAAAKST ASTKSQAQFN ARSVKSALTP 800
KKRHLLEQPT SVSGAGSSAS NSPLRIVVDN NSISGGKLLD ISPSSLCSLK 850
QQRRGGAAKQ KVSAAKDLVQ LQSPAGSYPP PGVFEPSVEL EIQIPLGKLN 900
ESVITKAEVE SPLLSALDIK EDTKKEVGQR VVETLLHKTG GNLLLKRKRK 950
KINRTGFPTV RRKKRKVSVE QQTTVVINGP EPEFDPDDEP LQSLRETRSS 1000
NSVNMQAPAN PSLDCERVPQ AGEARETFVA RTNQKAPRLS VVALERLQRP 1050
QTPARGRPRG RKPKNREQAG AAPLPPPKSE PEIRPAKKRG RQPKQPVLAE 1100
PPPTPPPQQK KNKIEPNIRL PDGIDPNTNF SCKIRLKRRK NLEAGTQPKK 1150
EKPIQTVTVE EIPPEIPVNQ EEIDAEAEAK RLDSIPLEHD PLPASESQNN 1200
GPQDYASCSE SSEDKASTTS LRKLSKVKKT YLVAGLFSNH YKQSLMPPPA 1250
KVNKKPGLEE QVGPASLLPP PPYCEKYLRR TEMDFELPYD IWWAYTNSKL 1300
PTRNVVPSWN YRKIRTNVYA ESVRPNLAGF DHPTCNCKDQ GEKSCLDNCL 1350
NRMVYTECSP SNCPAGEKCR NQKIQRHAVA PGVERFMTAD KGWGVRTKLP 1400
IAKGTYILEY VGEVVTEKEF KQRMASIYLN DTHHYCLHLD GGLVIDGQRM 1450
GSDCRFVNHS CEPNCEMQKW SVNGLSRMVL FAKRAIEEGE ELTYDYNFSL 1500
FNPSEGQPCR CNTPQCRGVI GGKSQRVKPL PAVEAKPAGD GLSGRNGRQR 1550
KQKAKKHAQR QAGKDISSAV AVAKLQPLSE KEEKLVRQFN TFLVRNFEKI 1600
RRCKDKRASA AAATASSPAL GATNGDIPGR RPSTPSSPSL AAQISALCSP 1650
RNIKTRGLTQ AVHDPELEKM AKMAVVLRDI CSAMETLKMS DLLTTVSSKK 1700
KKPIKTTLIG KVGATAATSK VEFRSIQVQV EQGHYKTPQE FDDHMQQLFV 1750
EAKQQHGDDE GKAKALQSLK DSYEQQKIAS YVQLVEILGD SESLQSFKPK 1800
EVLSPEEEAG KMAVKKSPGA KERDSPIVPL KVTPPPLLPV EASPDEDVIR 1850
CICGLYKDEG LMIQCAKCMV WQHTECTKAD IDADNYQCER CEPREVDREI 1900
PLEEFTEEGH RYYLSLMRGD LQVRQGDAVY VLRDIPIKDE SGKVLPTKKH 1950
TYETIGAIDY QECDIFRVEH LWKNELGKRF IFGHHFLRPH ETFHEPSRRF 2000
YPNEVVRVSL YEVVPIELVI GRCWVLDRTT FCKGRPMECN DEDHCYICEL 2050
RVDKTARFFS KAKANHPACT KSYAFRKFPE KIKISKSYAP HDVDPSLLKT 2100
RKQKTELELG AGQTTMHKVP GRQEQHQPKM VGRKHRGISG IPADATAVHV 2150
VTPMAPNKQM LKKRRSRLEN VLITMKLKCL DAQTAQEQPI DLSYLLSGRG 2200
ARQRKTQQSS SNSTVNST 2218
Length:2,218
Mass (Da):245,662
Last modified:September 23, 2008 - v1
Checksum:i038880A5360B6BB1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH480844 Genomic DNA. Translation: EDW49799.1.
RefSeqiXP_002043588.1. XM_002043552.1.

Genome annotation databases

EnsemblMetazoaiFBtr0200429; FBpp0198921; FBgn0172354.
GeneIDi6619372.
KEGGidse:Dsec_GM17444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH480844 Genomic DNA. Translation: EDW49799.1 .
RefSeqi XP_002043588.1. XM_002043552.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0200429 ; FBpp0198921 ; FBgn0172354 .
GeneIDi 6619372.
KEGGi dse:Dsec_GM17444.

Organism-specific databases

FlyBasei FBgn0172354. Dsec\GM17444.

Phylogenomic databases

KOi K06101.
OrthoDBi EOG7ZPNJ4.
PhylomeDBi B4IIM8.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF01426. BAH. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 3 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rob3c / Tucson 14021-0248.25.

Entry informationi

Entry nameiB4IIM8_DROSE
AccessioniPrimary (citable) accession number: B4IIM8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi