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B4IH79

- B4IH79_DROSE

UniProt

B4IH79 - B4IH79_DROSE

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Protein
Submitted name: GM11794
Gene
Dsec\GM11794, Dsec_GM11794, GM11794
Organism
Drosophila sechellia (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotations, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotations

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    GM11794Imported
    Gene namesi
    Name:Dsec\GM11794Imported
    ORF Names:Dsec_GM11794Imported, GM11794Imported
    OrganismiDrosophila sechellia (Fruit fly)
    Taxonomic identifieri7238 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000001292: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0166737. Dsec\GM11794.

    Subcellular locationi

    Nucleus By similarity UniRule annotation

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    ChromosomeSAAS annotations, NucleusUniRule annotationSAAS annotations

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 post-SET domain.
    Contains 1 pre-SET domain.UniRule annotation
    Contains SET domain.SAAS annotations
    Contains pre-SET domain.SAAS annotations

    Phylogenomic databases

    KOiK11421.
    OrthoDBiEOG7ZD1TG.
    PhylomeDBiB4IH79.

    Family and domain databases

    Gene3Di3.30.890.10. 1 hit.
    InterProiIPR016177. DNA-bd_dom.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view]
    PfamiPF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF54171. SSF54171. 1 hit.
    PROSITEiPS50982. MBD. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4IH79-1 [UniParc]FASTAAdd to Basket

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    MAKQPLLLKD FHQDHADFVA LDSSDEEEEE KQPEKSDFSK EKLQLIEDEL    50
    DDAIKNVLNK VDFTAQMAWS KTILQAKADH LERQFALADV ELEKVQTTAD 100
    KMHCALYNSC PVAHKHLPIL DIEPSDYVHE VPPAGEIVRP PIQLGETYYA 150
    VKNKAIASWV SIKVIEFTES TAINGNTMKS YKIRYLNTPY QMIKTVTAKH 200
    IAYFEPPPVR LTIGTRVIAY FDGTTLSRGK DKGVVQSAFY PGIIAEPLKQ 250
    ANRYRYLIFY DDGYTQYVPH RDVRLVCQAS EKVWEDVHAA SRDFIQKYVE 300
    KYSVDRPMVQ CTRGQSMNTE SNGTWLYARV MDIDCSLVLM QFEGDKNHTE 350
    WIYRGSLRLG PVFRETQNNM NSSSAQQLRV PRRTEPFIRY TKEMESSSKV 400
    NQQMRAFARK SSASAQNNAL AAASSAATSA GGRTNAGGAS TSNSSSAVRH 450
    LNNSTIYVDD ENRPKGHVVY FTAKRNLPPK MYKRHECSPN CLFKIVHRLD 500
    SYSPLAKPLL SGWERLVMRQ KTKKSVVYKG PCGKSLRNLA EVHRYLRATE 550
    NVLNVDNFDF TPDLKCLAEY SIDPSIVKDT DISKGQEKMA IPLVNYYDNT 600
    LPPPCTYAKQ RIPTEGVHLN LDEEFLLCCD CEDDCSDKSK CACWQLTVAG 650
    VRYCNPKKPI EEIGYQYKRL HEHVPTGIYE CNSRCKCKKN CLNRVVQFSL 700
    EMKLQVFKTS NRGWGLRCVN DIPKGAFICI YAGHLLTETM ANEGGQDAGD 750
    EYFADLDYIE VAEQLKEGYE SEVDHSDPDA EEDNGGPDAE DDDDFRPNYH 800
    YQRKIKRSSR SSSTQSCSTQ SSELDSQERA VINFNPNADL DETVRENSVR 850
    RLFGKDEAPY IMDAKTTGNL GRYFNHSCNP NLFVQNVFVD THDLRFPWVA 900
    FFSAAHIRSG TELTWNYNYE VGVVPGKVLY CQCGAPNCRI RLL 943
    Length:943
    Mass (Da):107,184
    Last modified:September 23, 2008 - v1
    Checksum:iCB664AB18E779497
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH480838 Genomic DNA. Translation: EDW49255.1.
    RefSeqiXP_002043124.1. XM_002043088.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0194779; FBpp0193271; FBgn0166737.
    GeneIDi6618876.
    KEGGidse:Dsec_GM11794.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH480838 Genomic DNA. Translation: EDW49255.1 .
    RefSeqi XP_002043124.1. XM_002043088.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0194779 ; FBpp0193271 ; FBgn0166737 .
    GeneIDi 6618876.
    KEGGi dse:Dsec_GM11794.

    Organism-specific databases

    FlyBasei FBgn0166737. Dsec\GM11794.

    Phylogenomic databases

    KOi K11421.
    OrthoDBi EOG7ZD1TG.
    PhylomeDBi B4IH79.

    Family and domain databases

    Gene3Di 3.30.890.10. 1 hit.
    InterProi IPR016177. DNA-bd_dom.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view ]
    Pfami PF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54171. SSF54171. 1 hit.
    PROSITEi PS50982. MBD. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rob3c / Tucson 14021-0248.25.

    Entry informationi

    Entry nameiB4IH79_DROSE
    AccessioniPrimary (citable) accession number: B4IH79
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: June 11, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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