Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

Pgam5

Organism
Drosophila sechellia (Fruit fly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrialBy similarity (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homologBy similarity
Gene namesi
Name:Pgam5By similarity
ORF Names:GM18947
OrganismiDrosophila sechellia (Fruit fly)
Taxonomic identifieri7238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000001292 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0173850. Dsec\GM18947.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 23HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003907081 – 289Serine/threonine-protein phosphatase Pgam5, mitochondrialAdd BLAST289

Interactioni

Subunit structurei

Interacts with Pk92B/ASK1.By similarity

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4I9J6.
SMRiB4I9J6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK15637.
OMAiHLTNRIP.
OrthoDBiEOG091G0DEJ.
PhylomeDBiB4I9J6.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
InterProiView protein in InterPro
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
PfamiView protein in Pfam
PF00300. His_Phos_1. 2 hits.
SMARTiView protein in SMART
SM00855. PGAM. 1 hit.
SUPFAMiSSF53254. SSF53254. 1 hit.

Sequencei

Sequence statusi: Complete.

B4I9J6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKLTSFACG TGAGLAAYYL QRLRDPQTAV QNSWTHSDKP VDPWALWDTN
60 70 80 90 100
WDCREPRALV RPLRNSQPEE ENRYNAELEK AKAKKARHII LVRHGEYLDV
110 120 130 140 150
GDSDDTHHLT ERGRKQAEFT GKRLCELGIK WDKVVASTMM RAQETSDIIL
160 170 180 190 200
KQIDFEKEKV VNCAFLREGA PIPPQPPVGH WKPEASQFLR DGSRIEAGFR
210 220 230 240 250
RYFHRAYPDQ EKESYTLIVG HGNVIRYFVC RALQFPAEGW LRININHASI
260 270 280
TWLTISPSGN VSIKYLGDSG FMPAELLTNR IPRDVKNVV
Length:289
Mass (Da):33,142
Last modified:September 23, 2008 - v1
Checksum:i7D74BD13C5187242
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH480825 Genomic DNA. Translation: EDW43877.1.
RefSeqiXP_002040406.1. XM_002040370.1.

Genome annotation databases

EnsemblMetazoaiFBtr0201932; FBpp0200424; FBgn0173850.
GeneIDi6616040.
KEGGidse:Dsec_GM18947.

Similar proteinsi

Entry informationi

Entry nameiPGAM5_DROSE
AccessioniPrimary (citable) accession number: B4I9J6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 19, 2010
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome