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B4HX75

- B4HX75_DROSE

UniProt

B4HX75 - B4HX75_DROSE

Protein

Aldose 1-epimerase

Gene

Dsec\GM19161

Organism
Drosophila sechellia (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.UniRule annotation

    Catalytic activityi

    Alpha-D-glucose = beta-D-glucose.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. aldose 1-epimerase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. hexose metabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotation

    Keywords - Biological processi

    Carbohydrate metabolismUniRule annotation

    Enzyme and pathway databases

    UniPathwayiUPA00242.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
    Alternative name(s):
    Galactose mutarotaseUniRule annotation
    Gene namesi
    Name:Dsec\GM19161Imported
    ORF Names:Dsec_GM19161Imported, GM19161Imported
    OrganismiDrosophila sechellia (Fruit fly)Imported
    Taxonomic identifieri7238 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000001292: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0174063. Dsec\GM19161.

    Structurei

    3D structure databases

    ProteinModelPortaliB4HX75.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldose epimerase family.UniRule annotation

    Phylogenomic databases

    KOiK01785.
    OrthoDBiEOG7V7666.
    PhylomeDBiB4HX75.

    Family and domain databases

    Gene3Di2.70.98.10. 1 hit.
    InterProiIPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view]
    PfamiPF01263. Aldose_epim. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005096. GALM. 1 hit.
    SUPFAMiSSF74650. SSF74650. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4HX75-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSITVEERNF GLVTNPLTEA RQMVHSYTLK NTKGMSVTVI QLGATIQSIF    50
    FPDGSKKVED VCLGFDDIAG YMTNKAAYIG GTLGRVANRV ASGGITLDET 100
    TVNLTRNFEG QFHLHGGFLG FDSVIWEVVQ KTPEGVVFRH QSQHGHEGYP 150
    GILTCLITYR LDNDDRLSIS FEANTDRQTI VNLSNHAYFN LAGQNAGPKG 200
    LAEHTVEIAS IEVVETDDRQ IPTGELTLVD NTAYDLRSPV VLGDRLKQFE 250
    HRPIQGFDNC YVVNGGQLLR STVKVAKIVH PPSGRALEVW TNQPGVQFYT 300
    ANNITKITGK KGSFYVKHGS FCVQTGKFPD AINHQNFPSI NLNPNETYRH 350
    EVVYWFKVEK TCRCCYKK 368
    Length:368
    Mass (Da):40,982
    Last modified:September 23, 2008 - v1
    Checksum:i2BBDACA7DFA9D1A3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH480818 Genomic DNA. Translation: EDW52620.1.
    RefSeqiXP_002036697.1. XM_002036661.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0202146; FBpp0200638; FBgn0174063.
    GeneIDi6612180.
    KEGGidse:Dsec_GM19161.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH480818 Genomic DNA. Translation: EDW52620.1 .
    RefSeqi XP_002036697.1. XM_002036661.1.

    3D structure databases

    ProteinModelPortali B4HX75.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0202146 ; FBpp0200638 ; FBgn0174063 .
    GeneIDi 6612180.
    KEGGi dse:Dsec_GM19161.

    Organism-specific databases

    FlyBasei FBgn0174063. Dsec\GM19161.

    Phylogenomic databases

    KOi K01785.
    OrthoDBi EOG7V7666.
    PhylomeDBi B4HX75.

    Enzyme and pathway databases

    UniPathwayi UPA00242 .

    Family and domain databases

    Gene3Di 2.70.98.10. 1 hit.
    InterProi IPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view ]
    Pfami PF01263. Aldose_epim. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005096. GALM. 1 hit.
    SUPFAMi SSF74650. SSF74650. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rob3c / Tucson 14021-0248.25Imported.

    Entry informationi

    Entry nameiB4HX75_DROSE
    AccessioniPrimary (citable) accession number: B4HX75
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3