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B4HCY7

- B4HCY7_DROPE

UniProt

B4HCY7 - B4HCY7_DROPE

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Protein

Histone deacetylase

Gene

Rpd3

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

  1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
  2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
  3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
  4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
Name:Rpd3Imported
Synonyms:Dper\GL22935Imported
ORF Names:Dper_GL22935Imported, GL22935Imported
OrganismiDrosophila persimilis (Fruit fly)Imported
Taxonomic identifieri7234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008744: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0160525. Dper\Rpd3.

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB4HCY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

KOiK06067.
OrthoDBiEOG7DNNTW.
PhylomeDBiB4HCY7.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

B4HCY7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQSHSKKRVC YYYDSDIGNY YYGQGHPMKP HRIRMTHNLL LNYGLYRKME
60 70 80 90 100
IYRPHKATDD EMTKFHSDEY VRFLRSIRPE NMTEYKKQMQ RFNVGEDCPV
110 120 130 140 150
FDGLYEFCQL SAGGSVAAAV KLNKQASEIC INWGGGLHHA KKSEASGFCY
160 170 180 190 200
VNDIVLGILE LLKYHQRVLY IDIDVHHGDG VEEAFYTADR VMTVSFHKYG
210 220 230 240 250
EYFPGTGDLR DIGAGKGKYY AVNIPLRDGM DDDAYESIFV PIISKVMETF
260 270 280 290 300
QPAAVVLQCG ADSLTGDRLG CFNLTVKGHG KCVDFVKKYN LPFLMVGGGG
310 320 330 340 350
YTIRNVSRCW TYETSVALAV DIANELPYNY YFEYFGPDFK LHISPSNMTN
360 370 380 390 400
QNTSEYLEKI KNRLFENLRM LPHAPGVQIQ AIPEDAINDE SDDEDKVDKD
410 420 430 440 450
DRLPQSDKDK RIVPENEYSD SEDEGEGGRR DNRAYKGQRQ RPRLDKDNNS
460 470 480 490 500
NKASSEASSE IKDEKEKVDG ADGEESTASN ANSNSNNNSS SNNKSDNDSS
510 520 530
APASRATTGG GSGSGSGSGS GAKTAKENNI
Length:530
Mass (Da):59,309
Last modified:September 23, 2008 - v1
Checksum:i82E7E0CE5F01317B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479537 Genomic DNA. Translation: EDW33672.1.
RefSeqiXP_002028716.1. XM_002028680.1.

Genome annotation databases

EnsemblMetazoaiFBtr0188550; FBpp0187042; FBgn0160525.
GeneIDi6603751.
KEGGidpe:Dper_GL22935.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479537 Genomic DNA. Translation: EDW33672.1 .
RefSeqi XP_002028716.1. XM_002028680.1.

3D structure databases

ProteinModelPortali B4HCY7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0188550 ; FBpp0187042 ; FBgn0160525 .
GeneIDi 6603751.
KEGGi dpe:Dper_GL22935.

Organism-specific databases

FlyBasei FBgn0160525. Dper\Rpd3.

Phylogenomic databases

KOi K06067.
OrthoDBi EOG7DNNTW.
PhylomeDBi B4HCY7.

Miscellaneous databases

ChiTaRSi Rpd3. fly.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
PRINTSi PR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSH-3 / Tucson 14011-0111.49Imported.

Entry informationi

Entry nameiB4HCY7_DROPE
AccessioniPrimary (citable) accession number: B4HCY7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 26, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3