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Protein

Histone-lysine N-methyltransferase

Gene

Dper\GL27000

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Name:Dper\GL27000Imported
ORF Names:Dper_GL27000Imported, GL27000Imported
OrganismiDrosophila persimilis (Fruit fly)Imported
Taxonomic identifieri7234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008744 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0164581. Dper\GL27000.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

KOiK11423.
OrthoDBiEOG7DFXBB.
PhylomeDBiB4H7D4.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4H7D4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQCDCFLTGD EEAQGHLCCG AGCINRMLMI ECGPLCTNGD RCTNKRFQLH
60 70 80 90 100
QCWPCRVFRT EKKGCGITAE LQIPAGEFIM EYVGEVIDSE EFERRQHRYS
110 120 130 140 150
KDRNRHYYFM ALRGEAIIDA TMRGNISRYI NHSCDPNAET QKWTVNGELR
160 170 180 190 200
IGFFSLKNIL PGEEITFDYQ YQRYGRDAQR CYCEAANCRG WIGTEPESDE
210 220 230 240 250
GEQKNENSEP ALATEDTDSG GEAESEAEGP EQSKSKGRAK TTSSSKFKVK
260 270 280 290 300
LPAVGSKEQR KKRETAAKAK EREREFKAGR WLKPTPGGSS SAEKKAKPKV
310 320 330 340 350
NKFHPMLEDP DVLEQLSLLS RSGLKNQLDT LRISRIMVRA KLLTTRIQLL
360 370 380 390 400
QVLTRGELPC RRLFLDYHGL RLLHAWISEN GNEQQLRTAL LDALEALPIP
410 420 430 440 450
NRTMLNESRV YQSVQQWSAG LTGQQSQLRS PEQSALRKRM QGLISKWSSL
460 470 480 490 500
PEIFRIPKRE RIEQMKEHER EADRTGERPT EKHVASHHLT AASALEDSAR
510 520 530 540 550
DSSTDRYRQD RFRRDTIGSR NSSQHQKPPM SRMSGNNTIC TITTQPKGSN
560 570 580 590 600
PSEGQPRTEM RRRPDNSGPT VEPRRGGAPL SKELRRSLFE RKVAQDEAEK
610 620 630 640 650
RVCSEDWREH ELRCEYFGAD ISTDPKMLPF SHNTETGEWF NSEDAPVMAP
660 670 680 690 700
LRTDLALAPS PEISEQDMMP AEYKLPASVD PLPPSWHWSR TIDGDIFYYN
710 720 730 740 750
LRDRIPQWLP PSPEQRLQTL LKEEPQQPLQ ELDPALLAEE LISVDPDYVG
760 770 780 790 800
SLSSKSLAQH IETKVRERRE IRHKKLCSVR VISPRRDEDR LYNQLESRKY
810 820 830 840 850
KENKEKIRRR KEIYRRQRAS ADTVAVSSEA STDAEAWSTP RYLYSSDEDT
860 870 880 890 900
DTAHAPPLVD ELEAELDLEP STSAYALACL NKPQQIPTLV TGGNGGAIKR
910 920 930 940
KLPPLPPHTP EKPAGALPER KSRSHELLNS SKSGRDSVEK FRSK
Length:944
Mass (Da):107,625
Last modified:September 23, 2008 - v1
Checksum:iAF1673BC4AA313DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479218 Genomic DNA. Translation: EDW33745.1.
RefSeqiXP_002026763.1. XM_002026727.1.

Genome annotation databases

EnsemblMetazoaiFBtr0192615; FBpp0191107; FBgn0164581.
GeneIDi6601763.
KEGGidpe:Dper_GL27000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479218 Genomic DNA. Translation: EDW33745.1.
RefSeqiXP_002026763.1. XM_002026727.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0192615; FBpp0191107; FBgn0164581.
GeneIDi6601763.
KEGGidpe:Dper_GL27000.

Organism-specific databases

FlyBaseiFBgn0164581. Dper\GL27000.

Phylogenomic databases

KOiK11423.
OrthoDBiEOG7DFXBB.
PhylomeDBiB4H7D4.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSH-3 / Tucson 14011-0111.49Imported.

Entry informationi

Entry nameiB4H7D4_DROPE
AccessioniPrimary (citable) accession number: B4H7D4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.