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B4H5Z1

- B4H5Z1_DROPE

UniProt

B4H5Z1 - B4H5Z1_DROPE

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Protein

Acetyl-coenzyme A synthetase

Gene

Dper\GL24594

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

GO - Molecular functioni

  1. acetate-CoA ligase activity Source: UniProtKB-EC
  2. AMP binding Source: InterPro
  3. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. acetyl-CoA biosynthetic process from acetate Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
Gene namesi
Name:Dper\GL24594Imported
ORF Names:Dper_GL24594Imported, GL24594Imported
OrganismiDrosophila persimilis (Fruit fly)Imported
Taxonomic identifieri7234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008744: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0162183. Dper\GL24594.

Structurei

3D structure databases

ProteinModelPortaliB4H5Z1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.UniRule annotation

Phylogenomic databases

KOiK01895.
OrthoDBiEOG77T140.
PhylomeDBiB4H5Z1.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4H5Z1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPAEKSIYDP NPAISQNAYI SSFEEYKKFY QESLDNPAEF WSRVAKQFHW
60 70 80 90 100
ETPADQEKFL QYNFNISKGP IYIKWMEGAS TNICYNLLDR NVRNGLGDQI
110 120 130 140 150
AYYWEGNHPD DYSRGLTYRK LLEEVCRFAN VLKDHGIRKG DRVSIYMPMI
160 170 180 190 200
LELPIAMLAC ARIGAVHSIV FAGFSPDSLA ERMFDCKAKL LITADGAWRG
210 220 230 240 250
EKPLYLKALC DTALEKVEEL GHSVEKCIVV SHLKRVTPCQ DNHVEEEIPW
260 270 280 290 300
TDDRDYWWHE EMEDKEPACY PEWMDAEDPL FMLYTSGSTG KPKGVLHTTA
310 320 330 340 350
GYLLYAATTF KIVFDYKPGD IYWCTADVGW ITGHTYVVYG PLANGATSVI
360 370 380 390 400
FEGTPFFPGN DRYWSVIDKY KVTQFYTAPT AIRALMKFGE GPVLKHNLSG
410 420 430 440 450
LKVLGSVGEP INPEAWLWYY RYIGKEQCSI VDTFWQTETG GHVITPLPGA
460 470 480 490 500
TPMKPGSASF PFFGVKPILL DECGIEIKGE GEGYLVFSQP WPGMMRTLYN
510 520 530 540 550
NHERFEDTYF SKFPGFYCTG DGARRDADDY LWITGRVDDM LNVSGHLMST
560 570 580 590 600
AEVESVLTEH PRVAESAVVS RPHPVKGECL YCFITPNENE PFDQKLISDL
610 620 630 640 650
KKMVRERIGP FAQPDVIQNA PGLPKTRSGK IMRRVLRKIA VNDRNVGDTS
660 670
TLADEQIVEQ LFANRPVEAK
Length:670
Mass (Da):76,126
Last modified:September 23, 2008 - v1
Checksum:iA87450FDC222F71E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479212 Genomic DNA. Translation: EDW33208.1.
RefSeqiXP_002026270.1. XM_002026234.1.

Genome annotation databases

EnsemblMetazoaiFBtr0190209; FBpp0188701; FBgn0162183.
GeneIDi6601138.
KEGGidpe:Dper_GL24594.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479212 Genomic DNA. Translation: EDW33208.1 .
RefSeqi XP_002026270.1. XM_002026234.1.

3D structure databases

ProteinModelPortali B4H5Z1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0190209 ; FBpp0188701 ; FBgn0162183 .
GeneIDi 6601138.
KEGGi dpe:Dper_GL24594.

Organism-specific databases

FlyBasei FBgn0162183. Dper\GL24594.

Phylogenomic databases

KOi K01895.
OrthoDBi EOG77T140.
PhylomeDBi B4H5Z1.

Family and domain databases

InterProi IPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view ]
Pfami PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEi PS00455. AMP_BINDING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSH-3 / Tucson 14011-0111.49Imported.

Entry informationi

Entry nameiB4H5Z1_DROPE
AccessioniPrimary (citable) accession number: B4H5Z1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3