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B4GRT8 (B4GRT8_DROPE) Unreviewed, UniProtKB/TrEMBL

Last modified March 6, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate dehydrogenase RuleBase RU003405
EC=1.1.1.37 RuleBase RU003405
Gene names
Name:GL24873 FlyBase FBgn0162461
Synonyms:Dper\GL24873 EMBL EDW40473.1
ORF Names:Dper_GL24873 EMBL EDW40473.1
OrganismDrosophila persimilis (Fruit fly) [Complete proteome]
Taxonomic identifier7234 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + NAD+ = oxaloacetate + NADH. RuleBase RU003405

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 1 family. RuleBase RU004065

Sequences

Sequence LengthMass (Da)Tools
B4GRT8 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 5CFBF66F33981F94

FASTA34436,759
        10         20         30         40         50         60 
MARTAFKVAV VGAGGGIGQP LSLLLRQIEG IDELALHDLR GTKGVAADTG HISEQGTVSG 

        70         80         90        100        110        120 
YVGNEQLVPA LQGANLVVVT AGMPRVPGMT RDSLMQANGG IAITVTRAMA CACPEALIAI 

       130        140        150        160        170        180 
TTNPINIIVP TAAEVLKEAG VFNPRRLFGV TTLDVVRSRK FIGDHMNIDP EKVNIPVIGG 

       190        200        210        220        230        240 
HTGPTILPLF SQCQPEFRGD TEDIERLTHR IKEAGTEVVM AKGGAGSATL SMAYATSSFV 

       250        260        270        280        290        300 
KSLIRAHNGQ EGIWNALLWH HVWKMSPSSQ GPLELGKEGI KRXXXXXXXX XXXXXXXXXX 

       310        320        330        340 
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXF SLIL

« Hide

References

[1]"Evolution of genes and genomes on the Drosophila phylogeny."
Drosophila 12 genomes consortium
Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MSH-3 / Tucson 14011-0111.49.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH479188 Genomic DNA. Translation: EDW40473.1.
RefSeqXP_002021317.1. XM_002021281.1.

3D structure databases

ProteinModelPortalB4GRT8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6595805.
KEGGdpe:Dper_GL24873.

Organism-specific databases

FlyBaseFBgn0162461. Dper\GL24873.

Phylogenomic databases

KOK00026.
OrthoDBEOG4FJ6RG.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11540. PTHR11540. 1 hit.
PTHR11540:SF1. PTHR11540:SF1. 1 hit.
PfamPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMSSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
TIGRFAMsTIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEPS00068. MDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4GRT8_DROPE
AccessionPrimary (citable) accession number: B4GRT8
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 6, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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