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B4GRT8

- B4GRT8_DROPE

UniProt

B4GRT8 - B4GRT8_DROPE

Protein

Malate dehydrogenase

Gene

Dper\GL24873

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (S)-malate + NAD+ = oxaloacetate + NADH.

    GO - Molecular functioni

    1. L-malate dehydrogenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. malate metabolic process Source: InterPro
    3. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    NADUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
    Gene namesi
    Name:Dper\GL24873Imported
    ORF Names:Dper_GL24873Imported, GL24873Imported
    OrganismiDrosophila persimilis (Fruit fly)Imported
    Taxonomic identifieri7234 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000008744: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0162461. Dper\GL24873.

    Structurei

    3D structure databases

    ProteinModelPortaliB4GRT8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LDH/MDH superfamily. MDH type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK00026.
    OrthoDBiEOG74R1R7.
    PhylomeDBiB4GRT8.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    InterProiIPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR001252. Malate_DH_AS.
    IPR010097. Malate_DH_type1.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11540. PTHR11540. 1 hit.
    PfamiPF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
    SUPFAMiSSF56327. SSF56327. 1 hit.
    TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
    PROSITEiPS00068. MDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4GRT8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARTAFKVAV VGAGGGIGQP LSLLLRQIEG IDELALHDLR GTKGVAADTG    50
    HISEQGTVSG YVGNEQLVPA LQGANLVVVT AGMPRVPGMT RDSLMQANGG 100
    IAITVTRAMA CACPEALIAI TTNPINIIVP TAAEVLKEAG VFNPRRLFGV 150
    TTLDVVRSRK FIGDHMNIDP EKVNIPVIGG HTGPTILPLF SQCQPEFRGD 200
    TEDIERLTHR IKEAGTEVVM AKGGAGSATL SMAYATSSFV KSLIRAHNGQ 250
    EGIWNALLWH HVWKMSPSSQ GPLELGKEGI KRXXXXXXXX XXXXXXXXXX 300
    XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXF SLIL 344
    Length:344
    Mass (Da):36,759
    Last modified:September 23, 2008 - v1
    Checksum:i5CFBF66F33981F94
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH479188 Genomic DNA. Translation: EDW40473.1.
    RefSeqiXP_002021317.1. XM_002021281.1.

    Genome annotation databases

    GeneIDi6595805.
    KEGGidpe:Dper_GL24873.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH479188 Genomic DNA. Translation: EDW40473.1 .
    RefSeqi XP_002021317.1. XM_002021281.1.

    3D structure databases

    ProteinModelPortali B4GRT8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 6595805.
    KEGGi dpe:Dper_GL24873.

    Organism-specific databases

    FlyBasei FBgn0162461. Dper\GL24873.

    Phylogenomic databases

    KOi K00026.
    OrthoDBi EOG74R1R7.
    PhylomeDBi B4GRT8.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    InterProi IPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR001252. Malate_DH_AS.
    IPR010097. Malate_DH_type1.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11540. PTHR11540. 1 hit.
    Pfami PF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000102. Lac_mal_DH. 1 hit.
    SUPFAMi SSF56327. SSF56327. 1 hit.
    TIGRFAMsi TIGR01772. MDH_euk_gproteo. 1 hit.
    PROSITEi PS00068. MDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MSH-3 / Tucson 14011-0111.49Imported.

    Entry informationi

    Entry nameiB4GRT8_DROPE
    AccessioniPrimary (citable) accession number: B4GRT8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3