B4GM96 (B4GM96_DROPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GL12290 EMBL EDW37970.1

Gene names

Name:	GL12290 FlyBase FBgn0149897
Synonyms:	Dper\GL12290 EMBL EDW37970.1
ORF Names:	Dper_GL12290 EMBL EDW37970.1

Organism

Drosophila persimilis (Fruit fly) [Complete proteome]

Taxonomic identifier

7234 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup

Protein attributes

Sequence length	1548 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 post-SET domain. RuleBase RU004541

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS001214 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4GM96 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 9A78E442F5406DF3	FASTA	1,548	176,534
	10 20 30 40 50 60 MGKILNVFCD PFGAILRKHI ETLTNPVAPK PVLGATTTKA PPHPGTAVGS QPDLADYSHD 70 80 90 100 110 120 YSEKSAVDNL NSAYSSFPKN SDIGERSRDR NWERDRERER DRDRDRDRYY KDSSQHSAER 130 140 150 160 170 180 SYDRDRAMRD KYGSSLRHDR HFYRRRSRDK SPDPSRDSRD RLFTGRERDR ARDPDARSRD 190 200 210 220 230 240 YHRSKERDYF RERNRSRDHS RDRSREKRDL RFSVSKERDY RERDRDRDRD RSPDRDRRDR 250 260 270 280 290 300 VSIKYKKRFT SHEYAETDIH SSSSSKTHQY YTAASASGLP AGSYAYSSHA YSMTDSTQSW 310 320 330 340 350 360 SEHKSWNAPQ PDFQPKPKPP PPPPPEEEEN WDDPPVLPQK FEQQTVSLLE SASTKLQSPK 370 380 390 400 410 420 AGTAVAEPNA ETENVDLDTR IALIFKGKTF GNAPPFLQMD SSDSETDKAK PEGGVEANET 430 440 450 460 470 480 RSLSDSNNSD NKKKCDKKIS ELQQPHGASD ISSDDDIMVK NKRCKPGFTQ CEKDDDNMSL 490 500 510 520 530 540 SSLSSHEESP TALANTADRG NKKPLSPYMY PNSSNQHPYY YHPSDYGHYP SGISSNPVLT 550 560 570 580 590 600 SRYFSNPAYM QPAYLAGVGA FNLDPYVQTY GYQYPPSDQN DEIKENVKKV INYIVEELKQ 610 620 630 640 650 660 ILKRDVNKRM IEITAFKNFE SWWDEHTLKA RSKPLPDSVE GITNLRQSSA NANLMKENAD 670 680 690 700 710 720 CEKPPNMNQL TNTQVEMSDF KSFSSIGIRA AMPKLPSFRR ICKHPSPIPN QRISLERDLS 730 740 750 760 770 780 DQEEMVQRSD SEKEDSNMGG FEAPGSNAKD RVLDREMATI RLPSPEMLSK RKGSASSFFS 790 800 810 820 830 840 SSSSSSSEAE NEVNDAADGT EKEKSSDDDS FDDDHPPRNL NRKSRLIKKN RRVAFKEPGD 850 860 870 880 890 900 DNIENIYSDS EDEKRHTDRM HVQKRGRTKK KNIYSDSDAD IESTAGRGFL PALRTKVIST 910 920 930 940 950 960 IPSDLEDISK DSSFGLDEED PDDKVEAELK TIRKMVDESR RSLTPVPPPD YNEEPVEKYD 970 980 990 1000 1010 1020 DTDLRKPVYE YDRIYSDSDE EREYQEKRRR NTEYMAQIER EFLEEQQKNN QNSFSEGRSI 1030 1040 1050 1060 1070 1080 SERKLEIVKK PSGDMADTVD VPEVPLTPGI NILAELVDEI NKPILETNIE QNASKIAEID 1090 1100 1110 1120 1130 1140 GKLKSNLNSS DVVEATTILN GDVQSFSNTN TSKKGTQSPA SSDGGSSQAS QASQVALEHC 1150 1160 1170 1180 1190 1200 YSLPPHAQSA SFTDATSGRL GLDAQNKNRF DGQENVAGGS QMQRPGPGRP RKDSTRLQKK 1210 1220 1230 1240 1250 1260 KKDSVPRQSN AKNKVAPITD ALAELARQTA NFVPYEMYKA RDQNEEMVIL YTFLTKGIDA 1270 1280 1290 1300 1310 1320 EDIKYIKMSY IEHLQKEPYA MFLNNTHWVD HCTTDRAFWP PPPKKRRKDD ELMRHKTGCA 1330 1340 1350 1360 1370 1380 RTEGYYKLDV REKAKHKYHH AKANIDDAEN EDRCDEPTAL TNHHHNKLIS KMQGISREAR 1390 1400 1410 1420 1430 1440 SNQRRLLTAF GSMGESELLK FNQLKFRKKQ LKFAKSAIHD WGLFAMEPIA ADEMVIEYVG 1450 1460 1470 1480 1490 1500 QMIRPVVADL RETKYEAIGI GSSYLFRIDM ETIIDATKCG NLARFINHSC NPNCYAKVIT 1510 1520 1530 1540 IESEKKIVIY SKQPIGVNEE ITYDYKFPLE DEKIPCLCGA QGCRGTLN

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MSH-3 / Tucson 14011-0111.49.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH479185 Genomic DNA. Translation: EDW37970.1.
RefSeq	XP_002019336.1. XM_002019300.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0177905; FBpp0176397; FBgn0149897.
GeneID	6594368.
KEGG	dpe:Dper_GL12290.
Organism-specific databases
FlyBase	FBgn0149897. Dper\GL12290.
Phylogenomic databases
KO	K11422.
OrthoDB	EOG4P5HQZ.
Family and domain databases
InterPro	IPR024657. COMPASS_Set1_N-SET. IPR015722. Histone-lysine_MeTfrase. IPR003616. Post-SET_dom. IPR001214. SET_dom. [Graphical view]
PANTHER	PTHR22884:SF10. PTHR22884:SF10. 1 hit.
Pfam	PF11764. N-SET. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4GM96_DROPE

Accession

Primary (citable) accession number: B4GM96

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	January 9, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)