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B4GF88

- B4GF88_DROPE

UniProt

B4GF88 - B4GF88_DROPE

Protein

Histone deacetylase

Gene

Dper\GL22163

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    Name:Dper\GL22163Imported
    ORF Names:Dper_GL22163Imported, GL22163Imported
    OrganismiDrosophila persimilis (Fruit fly)Imported
    Taxonomic identifieri7234 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000008744: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0159755. Dper\GL22163.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliB4GF88.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    KOiK11404.
    OrthoDBiEOG7DNNTW.
    PhylomeDBiB4GF88.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    B4GF88-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDRRVSYFY NADVGNFHYG AGHPMKPQRL AVTHSLVMNY GLDKKMKIYR    50
    PYKASAQDML RFHSDEYIAY LQQVTPQNIQ CNSVAYTKYL AHFSVGEDCP 100
    VFDGLFDFCA MYTGASLEGA QKLNHNHSDI CINWSGGLHH AKKFEASGFC 150
    YVNDIVIGIL ELLKYHPRVL YIDIDVHHGD GVQEAFYLTD RVMTASFHKY 200
    GNYFFPGTGD MYELGAESGR YYSVNVPLKE GIDDQSYFQV FKPIISAIMD 250
    FYRPTAIVLQ CGADSLAGDR LGCFSLSTRG HGECVKFVKE LNVPTLVVGG 300
    GGYTLRNVAR CWTHETSLLV DQDIDNDLPI TEYYEFFGPD FTLHPEINSR 350
    QDNANSKQYL EMIVKHVYEN LKMCQHSPSV QMVQTPPDMD IEELRNKEET 400
    DPDVRISQTD DDKSVEAKNE FYDGDQDQDK PDSAES 436
    Length:436
    Mass (Da):49,588
    Last modified:September 23, 2008 - v1
    Checksum:i417FE70CAF8CC48C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH479182 Genomic DNA. Translation: EDW34273.1.
    RefSeqiXP_002017173.1. XM_002017137.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0187778; FBpp0186270; FBgn0159755.
    GeneIDi6591398.
    KEGGidpe:Dper_GL22163.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH479182 Genomic DNA. Translation: EDW34273.1 .
    RefSeqi XP_002017173.1. XM_002017137.1.

    3D structure databases

    ProteinModelPortali B4GF88.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0187778 ; FBpp0186270 ; FBgn0159755 .
    GeneIDi 6591398.
    KEGGi dpe:Dper_GL22163.

    Organism-specific databases

    FlyBasei FBgn0159755. Dper\GL22163.

    Phylogenomic databases

    KOi K11404.
    OrthoDBi EOG7DNNTW.
    PhylomeDBi B4GF88.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MSH-3 / Tucson 14011-0111.49Imported.

    Entry informationi

    Entry nameiB4GF88_DROPE
    AccessioniPrimary (citable) accession number: B4GF88
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3