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Protein

DNA ligase

Gene

Dper\GL11174

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dper\GL11174Imported
ORF Names:Dper_GL11174Imported, GL11174Imported
OrganismiDrosophila persimilis (Fruit fly)Imported
Taxonomic identifieri7234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000008744 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0148784 Dper\GL11174

Subcellular locationi

Structurei

3D structure databases

ProteinModelPortaliB4GCY0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini472 – 608DNA_LIGASE_A3InterPro annotationAdd BLAST137

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747
OMAiWIKYKRD
OrthoDBiEOG091G06OS
PhylomeDBiB4GCY0

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

B4GCY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQSITSYFK QKSDVPESPG KARPVSKIKS EVDLAENEPK IKREDETSEA
60 70 80 90 100
NIEANRIIDP NPSIIEAMEI KEEPTSKVER KVTTIGLNST SKDNKEEVEN
110 120 130 140 150
YDPSNEAYHP LEHAYWKAKA VTPYLALART FQVIEETKGR LKMIDTLSNF
160 170 180 190 200
FSSVMLVSPN DLLPSVYLSI NQLAPAYEGL ELGVAETTLM KAICKATGRN
210 220 230 240 250
LAHIKSQTHL TGDLGIVAEQ SRVSQRMMFQ PAPLNIRGVF NKLREIAKIS
260 270 280 290 300
GQSKMTLVYD VFVACRSSEA RFFIRSLIGK LRIGIAEQSL LTALAIALVK
310 320 330 340 350
KNHINDCKVS KIVDVYKDEI TETTLLLKTA YSQCPNYDII IPAILKYDIK
360 370 380 390 400
ELQERCPMHP GMPLRPMLAQ PTKGVHEVFE RFGSMHITCE WKYDGERAQI
410 420 430 440 450
HCNERGEISI FSRNSENNTA KYPDLIARSK GFLKGAVQSY IIDSEIVAWD
460 470 480 490 500
VERKQILPFQ VLSTRKRKNV DIEEIKVQVC VYIFDLLYIN GTTLVTSPLS
510 520 530 540 550
ERRKLLLEHF QEVEGEWKFA TALDTNDIDE VQQFLEESVK GNCEGLMVKT
560 570 580 590 600
LDEEATYEIA KRSRNWLKLK KDYLSNVGDS LDLVVIGGYK GKGRRTGTYG
610 620 630 640 650
GFLLACYDTE NEEYQSICKI GTGFTDEDLR IHSEFLGKHV IPSAKSYFRY
660 670 680 690 700
DSSLEPDHWF EPAQVWEVKC ADLSLSPIHR AAIGIVDTER GISLRFPRFI
710 720 730 740
RIRDDKSSEN ATDANQVAHM YQSQDQVKNN QRTCTQMDME SEFY
Length:744
Mass (Da):84,566
Last modified:September 23, 2008 - v1
Checksum:iD36BE18D3D46F90C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479181 Genomic DNA Translation: EDW31518.1
RefSeqiXP_002015628.1, XM_002015592.1

Genome annotation databases

EnsemblMetazoaiFBtr0176789; FBpp0175281; FBgn0148784
GeneIDi6591299
KEGGidpe:Dper_GL11174

Similar proteinsi

Entry informationi

Entry nameiB4GCY0_DROPE
AccessioniPrimary (citable) accession number: B4GCY0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health