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B4GCY0

- B4GCY0_DROPE

UniProt

B4GCY0 - B4GCY0_DROPE

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Protein

DNA ligase

Gene

Dper\GL11174

Organism
Drosophila persimilis (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dper\GL11174Imported
ORF Names:Dper_GL11174Imported, GL11174Imported
OrganismiDrosophila persimilis (Fruit fly)Imported
Taxonomic identifieri7234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008744: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0148784. Dper\GL11174.

Structurei

3D structure databases

ProteinModelPortaliB4GCY0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7RFTGN.
PhylomeDBiB4GCY0.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4GCY0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQQSITSYFK QKSDVPESPG KARPVSKIKS EVDLAENEPK IKREDETSEA
60 70 80 90 100
NIEANRIIDP NPSIIEAMEI KEEPTSKVER KVTTIGLNST SKDNKEEVEN
110 120 130 140 150
YDPSNEAYHP LEHAYWKAKA VTPYLALART FQVIEETKGR LKMIDTLSNF
160 170 180 190 200
FSSVMLVSPN DLLPSVYLSI NQLAPAYEGL ELGVAETTLM KAICKATGRN
210 220 230 240 250
LAHIKSQTHL TGDLGIVAEQ SRVSQRMMFQ PAPLNIRGVF NKLREIAKIS
260 270 280 290 300
GQSKMTLVYD VFVACRSSEA RFFIRSLIGK LRIGIAEQSL LTALAIALVK
310 320 330 340 350
KNHINDCKVS KIVDVYKDEI TETTLLLKTA YSQCPNYDII IPAILKYDIK
360 370 380 390 400
ELQERCPMHP GMPLRPMLAQ PTKGVHEVFE RFGSMHITCE WKYDGERAQI
410 420 430 440 450
HCNERGEISI FSRNSENNTA KYPDLIARSK GFLKGAVQSY IIDSEIVAWD
460 470 480 490 500
VERKQILPFQ VLSTRKRKNV DIEEIKVQVC VYIFDLLYIN GTTLVTSPLS
510 520 530 540 550
ERRKLLLEHF QEVEGEWKFA TALDTNDIDE VQQFLEESVK GNCEGLMVKT
560 570 580 590 600
LDEEATYEIA KRSRNWLKLK KDYLSNVGDS LDLVVIGGYK GKGRRTGTYG
610 620 630 640 650
GFLLACYDTE NEEYQSICKI GTGFTDEDLR IHSEFLGKHV IPSAKSYFRY
660 670 680 690 700
DSSLEPDHWF EPAQVWEVKC ADLSLSPIHR AAIGIVDTER GISLRFPRFI
710 720 730 740
RIRDDKSSEN ATDANQVAHM YQSQDQVKNN QRTCTQMDME SEFY
Length:744
Mass (Da):84,566
Last modified:September 23, 2008 - v1
Checksum:iD36BE18D3D46F90C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH479181 Genomic DNA. Translation: EDW31518.1.
RefSeqiXP_002015628.1. XM_002015592.1.

Genome annotation databases

EnsemblMetazoaiFBtr0176789; FBpp0175281; FBgn0148784.
GeneIDi6591299.
KEGGidpe:Dper_GL11174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH479181 Genomic DNA. Translation: EDW31518.1 .
RefSeqi XP_002015628.1. XM_002015592.1.

3D structure databases

ProteinModelPortali B4GCY0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0176789 ; FBpp0175281 ; FBgn0148784 .
GeneIDi 6591299.
KEGGi dpe:Dper_GL11174.

Organism-specific databases

FlyBasei FBgn0148784. Dper\GL11174.

Phylogenomic databases

KOi K10747.
OrthoDBi EOG7RFTGN.
PhylomeDBi B4GCY0.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSH-3 / Tucson 14011-0111.49Imported.

Entry informationi

Entry nameiB4GCY0_DROPE
AccessioniPrimary (citable) accession number: B4GCY0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3