B4G2B2 (B4G2B2_DROPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GL23881 EMBL EDW23957.1

Gene names

Name:	Dper\GL23881 EMBL EDW23957.1
ORF Names:	Dper_GL23881 EMBL EDW23957.1, GL23881 FlyBase FBgn0161471

Organism

Drosophila persimilis (Fruit fly) [Complete proteome]

Taxonomic identifier

7234 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup

Protein attributes

Sequence length	1466 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS001214
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Molecular function	Methyltransferase SAAS SAAS001214 RuleBase RU004541 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4G2B2 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 5F579805027F8DAB	FASTA	1,466	163,109
	10 20 30 40 50 60 MKISAGAHSE TDGVGAQSNL SFNADGTATG DAAAGNAESV ASQITEHPEK VKEKRRKRSK 70 80 90 100 110 120 IVAHDGDSVT EFTENDLNGY LSPKNAPFAI KKQQRLSGLN RKRDLINLQS ALSPKYIGYA 130 140 150 160 170 180 NANSPTPLSD SDDTVRTTRR RFTQAAALNS SNNNNHCELQ PRDNDAATES PKTLEGTPLL 190 200 210 220 230 240 DRSDSKNYIS PIDKLLMKNG ASSPNSTGFE TDPEDVAPLA ARLHLRRKLK RAAKTKSTSE 250 260 270 280 290 300 TVEPPEKVPS VKEEPMDITD LQPKEVSDAK IEDTVPFSTD VNSESESRAS SCDVVSSSRI 310 320 330 340 350 360 SLSNENAQDL PGEPTDTSRK TIESTDEPND PDPDPDPDSE SGFALPAATL TDMKSPGELS 370 380 390 400 410 420 PTAFRQPEDN GYVKSPSSVS LDSAKGLSIV TDPGWGTYQV GDLYWGKVFS YCFWPCMVCP 430 440 450 460 470 480 DPYGQIVGNL PAHPQRTSTD NAPLPIQVHV RFFADSGRRN WIKPENLLSF AGLKAYEEQR 490 500 510 520 530 540 EEVRIKYGNR SGKYRTMVPK RTKLDVWRQA IDEAQLVAQV PYSERLEKFY QIYESVVTIN 550 560 570 580 590 600 KQKRKRTNSM TTQDTSDVGS SLYDSTDNLH AKAHLQLMNV KRERSVTPVS PAFSPVKKSQ 610 620 630 640 650 660 MRTKRRKLSK GAEAETGGGT VPSESVAGAE KNITPSNSGG TYENPEFRQL FDAIQEYVMV 670 680 690 700 710 720 YRHDDKVEKV LRAVVGNIWS LKQIQLRELE RELAYGEMDQ EQLGSAVVER KRGTGTTQRL 730 740 750 760 770 780 SNRLKTLVER RSRTPVVTPS GTPTPTATST IGGAEMRLSE ISKPKKPVNR PIEEVVEDIF 790 800 810 820 830 840 QLDSKYLFRG LPRGTVCKYC FKTGSNLLQC SRTCHSWMHA DCLESKRNGL AASKKEGLKL 850 860 870 880 890 900 KALEDVSTSS STTPPVPAAE HITGDAPDAL ATIATAAPTA PTFEVICHEC NVNGEASCCI 910 920 930 940 950 960 CLQVLPPAYP SPSPGSPLKE GSSEAKEATP VDGTMIMCGQ NLCGRQYHAG CCKYWPQAIA 970 980 990 1000 1010 1020 SSSLTRCPLH VCHTCVSDNP RKFLPVGSSK LTRCVKCPAS YHQDSRCIPA GSRMLTTTNL 1030 1040 1050 1060 1070 1080 ICPRHNVAKT DAHLNVLWCF ICVKGGELLC CETCPIAVHA GCRKVPIEKH ENYICEECES 1090 1100 1110 1120 1130 1140 GRLPLYGEIV WAKFNNFRWW PAIILPPTEI PNNILKKAHG ESEFVVRFFG THDHGWIPRR 1150 1160 1170 1180 1190 1200 RVYLYIEGDT GEKLKPRSQL HRKFYNGIEE ATRFLKITKA RRHEQMVARG IKVNPPPYVK 1210 1220 1230 1240 1250 1260 IKINKAVPPV KFVTNSEEHS TCDCRPEDEH PCGANSNCLN RMLFNECHPE YCRCGDRCEN 1270 1280 1290 1300 1310 1320 RMFETRKSPR MDVVYMNARG FGLVCREPIA EGDFIIEYVG EVINQEEFQR RMLRKQKDRD 1330 1340 1350 1360 1370 1380 ENFYFLGVEK EFIIDAGPKG NLARFMNHSC EPNCTSQKWT VNCTHRVGLF AIQDIPAETE 1390 1400 1410 1420 1430 1440 LTFNYLWDDL LNDKKKACHC GSERCSGEIG GKLKDKSSNV KLKQQQRSRG AAIRIHVPPA 1450 1460 KKAKKSVPKI KHVSADDELE EAKKDQ

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MSH-3 / Tucson 14011-0111.49.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH479179 Genomic DNA. Translation: EDW23957.1.
RefSeq	XP_002012971.1. XM_002012935.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0189496; FBpp0187988; FBgn0161471.
GeneID	6588501.
KEGG	dpe:Dper_GL23881.
Organism-specific databases
FlyBase	FBgn0161471. Dper\GL23881.
Phylogenomic databases
KO	K11424.
OrthoDB	EOG40CFZF.
Family and domain databases
Gene3D	3.30.40.10. 1 hit.
InterPro	IPR006560. AWS. IPR003616. Post-SET_dom. IPR000313. PWWP. IPR001214. SET_dom. IPR019786. Zinc_finger_PHD-type_CS. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF00855. PWWP. 2 hits. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00570. AWS. 1 hit. SM00249. PHD. 3 hits. SM00508. PostSET. 1 hit. SM00293. PWWP. 2 hits. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF57903. FYVE_PHD_ZnF. 1 hit.
PROSITE	PS51215. AWS. 1 hit. PS50868. POST_SET. 1 hit. PS50812. PWWP. 2 hits. PS50280. SET. 1 hit. PS01359. ZF_PHD_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4G2B2_DROPE

Accession

Primary (citable) accession number: B4G2B2

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 29, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)