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B4G2B2 (B4G2B2_DROPE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1466 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214

Sequence similarities

Contains 1 post-SET domain. RuleBase RU004541

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Ontologies

Keywords
   Cellular componentNucleus SAAS SAAS001214
   DomainZinc-finger SAAS SAAS011011
   LigandMetal-binding
Zinc
   Molecular functionMethyltransferase RuleBase RU004541
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionhistone-lysine N-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B4G2B2 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 5F579805027F8DAB

FASTA1,466163,109
        10         20         30         40         50         60 
MKISAGAHSE TDGVGAQSNL SFNADGTATG DAAAGNAESV ASQITEHPEK VKEKRRKRSK 

        70         80         90        100        110        120 
IVAHDGDSVT EFTENDLNGY LSPKNAPFAI KKQQRLSGLN RKRDLINLQS ALSPKYIGYA 

       130        140        150        160        170        180 
NANSPTPLSD SDDTVRTTRR RFTQAAALNS SNNNNHCELQ PRDNDAATES PKTLEGTPLL 

       190        200        210        220        230        240 
DRSDSKNYIS PIDKLLMKNG ASSPNSTGFE TDPEDVAPLA ARLHLRRKLK RAAKTKSTSE 

       250        260        270        280        290        300 
TVEPPEKVPS VKEEPMDITD LQPKEVSDAK IEDTVPFSTD VNSESESRAS SCDVVSSSRI 

       310        320        330        340        350        360 
SLSNENAQDL PGEPTDTSRK TIESTDEPND PDPDPDPDSE SGFALPAATL TDMKSPGELS 

       370        380        390        400        410        420 
PTAFRQPEDN GYVKSPSSVS LDSAKGLSIV TDPGWGTYQV GDLYWGKVFS YCFWPCMVCP 

       430        440        450        460        470        480 
DPYGQIVGNL PAHPQRTSTD NAPLPIQVHV RFFADSGRRN WIKPENLLSF AGLKAYEEQR 

       490        500        510        520        530        540 
EEVRIKYGNR SGKYRTMVPK RTKLDVWRQA IDEAQLVAQV PYSERLEKFY QIYESVVTIN 

       550        560        570        580        590        600 
KQKRKRTNSM TTQDTSDVGS SLYDSTDNLH AKAHLQLMNV KRERSVTPVS PAFSPVKKSQ 

       610        620        630        640        650        660 
MRTKRRKLSK GAEAETGGGT VPSESVAGAE KNITPSNSGG TYENPEFRQL FDAIQEYVMV 

       670        680        690        700        710        720 
YRHDDKVEKV LRAVVGNIWS LKQIQLRELE RELAYGEMDQ EQLGSAVVER KRGTGTTQRL 

       730        740        750        760        770        780 
SNRLKTLVER RSRTPVVTPS GTPTPTATST IGGAEMRLSE ISKPKKPVNR PIEEVVEDIF 

       790        800        810        820        830        840 
QLDSKYLFRG LPRGTVCKYC FKTGSNLLQC SRTCHSWMHA DCLESKRNGL AASKKEGLKL 

       850        860        870        880        890        900 
KALEDVSTSS STTPPVPAAE HITGDAPDAL ATIATAAPTA PTFEVICHEC NVNGEASCCI 

       910        920        930        940        950        960 
CLQVLPPAYP SPSPGSPLKE GSSEAKEATP VDGTMIMCGQ NLCGRQYHAG CCKYWPQAIA 

       970        980        990       1000       1010       1020 
SSSLTRCPLH VCHTCVSDNP RKFLPVGSSK LTRCVKCPAS YHQDSRCIPA GSRMLTTTNL 

      1030       1040       1050       1060       1070       1080 
ICPRHNVAKT DAHLNVLWCF ICVKGGELLC CETCPIAVHA GCRKVPIEKH ENYICEECES 

      1090       1100       1110       1120       1130       1140 
GRLPLYGEIV WAKFNNFRWW PAIILPPTEI PNNILKKAHG ESEFVVRFFG THDHGWIPRR 

      1150       1160       1170       1180       1190       1200 
RVYLYIEGDT GEKLKPRSQL HRKFYNGIEE ATRFLKITKA RRHEQMVARG IKVNPPPYVK 

      1210       1220       1230       1240       1250       1260 
IKINKAVPPV KFVTNSEEHS TCDCRPEDEH PCGANSNCLN RMLFNECHPE YCRCGDRCEN 

      1270       1280       1290       1300       1310       1320 
RMFETRKSPR MDVVYMNARG FGLVCREPIA EGDFIIEYVG EVINQEEFQR RMLRKQKDRD 

      1330       1340       1350       1360       1370       1380 
ENFYFLGVEK EFIIDAGPKG NLARFMNHSC EPNCTSQKWT VNCTHRVGLF AIQDIPAETE 

      1390       1400       1410       1420       1430       1440 
LTFNYLWDDL LNDKKKACHC GSERCSGEIG GKLKDKSSNV KLKQQQRSRG AAIRIHVPPA 

      1450       1460 
KKAKKSVPKI KHVSADDELE EAKKDQ 

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References

[1]"Evolution of genes and genomes on the Drosophila phylogeny."
Drosophila 12 genomes consortium
Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MSH-3 / Tucson 14011-0111.49.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH479179 Genomic DNA. Translation: EDW23957.1.
RefSeqXP_002012971.1. XM_002012935.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0189496; FBpp0187988; FBgn0161471.
GeneID6588501.
KEGGdpe:Dper_GL23881.

Organism-specific databases

FlyBaseFBgn0161471. Dper\GL23881.

Phylogenomic databases

KOK11424.
OrthoDBEOG7B05CD.
PhylomeDBB4G2B2.

Family and domain databases

Gene3D3.30.40.10. 1 hit.
InterProIPR006560. AWS.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamPF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTSM00570. AWS. 1 hit.
SM00249. PHD. 3 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMSSF57903. SSF57903. 2 hits.
PROSITEPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4G2B2_DROPE
AccessionPrimary (citable) accession number: B4G2B2
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)