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Protein
Submitted name:

Arylsulfatase B

Gene

Arsb

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Arylsulfatase BImported
Gene namesi
Name:ArsbImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2158. Arsb.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 36Sequence analysisAdd BLAST36
ChainiPRO_500994795637 – 528Sequence analysisAdd BLAST492

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei863-oxoalanine (Cys)UniRule annotation1

Post-translational modificationi

The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.UniRule annotation

Proteomic databases

PRIDEiB4F7E2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000011150.
ExpressionAtlasiB4F7E2. baseline and differential.
GenevisibleiB4F7E2. RN.

Structurei

3D structure databases

ProteinModelPortaliB4F7E2.
SMRiB4F7E2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 357SulfataseInterPro annotationAdd BLAST318

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3867. Eukaryota.
COG3119. LUCA.
HOVERGENiHBG004282.
KOiK01135.
OMAiKWTLWEG.
OrthoDBiEOG091G06C3.
PhylomeDBiB4F7E2.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiView protein in InterPro
IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core_sf.
IPR024607. Sulfatase_CS.
IPR000917. Sulfatase_N.
PfamiView protein in Pfam
PF00884. Sulfatase. 1 hit.
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiView protein in PROSITE
PS00523. SULFATASE_1. 1 hit.
PS00149. SULFATASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B4F7E2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGELSGCTGG SRAGGPGPRL PLLLLLLLWP ARASDAAPPP HVVFVLADDL
60 70 80 90 100
GWNDLGFHGS VIRTPHLDAL AAGGVVLDNY YVQPLCTPSR SQLLTGRYQI
110 120 130 140 150
HMGLQHYLIM TCQPNCVPLD EKLLPQLLKD AGYATHMVGK WHLGMYRKEC
160 170 180 190 200
LPTRRGFDTY FGYLLGSEDY YTHEACAPIE CLNGTRCALD LRDGEEPAKE
210 220 230 240 250
YTDIYSTNIF TKRATTLIAN HPPEKPLFLY LAFQSVHDPL QVPEEYMEPY
260 270 280 290 300
DFIQDKHRRI YAGMVSLLDE AVGNVTKALK SRGLWNNTVL IFSTDNGGQT
310 320 330 340 350
RSGGNNWPLR GRKGTLWEGG IRGAGFVASP LLKQKGVKSR ELMHITDWLP
360 370 380 390 400
TLVNLAGGST HGTKPLDGFD VWETISEGSP SPRVELLLNI DPDFFDGLPC
410 420 430 440 450
PGKNTTPEKN DSFPLEHSAF NTSIHAGIRY KNWKLLTGYP GCGYWFPPPS
460 470 480 490 500
QSNISEVPSV DSPTKTLWLF DINRDPEERH DVSREHPHIV QNLLSRLQYY
510 520
HEHSVPSYFP PLDPRCDPKG TGVWSPWM
Length:528
Mass (Da):58,959
Last modified:September 23, 2008 - v1
Checksum:i1F02425E858E5A00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC168241 mRNA. Translation: AAI68241.1.
RefSeqiNP_254278.1. NM_033443.1.
UniGeneiRn.94004.

Genome annotation databases

GeneIDi25227.
KEGGirno:25227.

Similar proteinsi

Entry informationi

Entry nameiB4F7E2_RAT
AccessioniPrimary (citable) accession number: B4F7E2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 22, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)